Synthetic Route of 872355-63-0, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 872355-63-0, name is Methyl 1H-pyrrolo[3,2-b]pyridine-5-carboxylate. A new synthetic method of this compound is introduced below.
To the methanol (1OmL) and water (10 mL) suspension of lH-pyrrolo[3,2-b]pyridine- 5-carboxylic acid methyl ester (0.54 g) was added sodium hydroxide (0.37 g) . The reaction was heated at 70 0C for 2 h. The reaction mixture was concentrated and the residue obtained was redissolved in water. The aqueous solution was acidified with cone, hydrochloric acid to pH 2. The solid thus separated was filtered, washed with water and dried under high vacuum. It was used as such for the next step without any purification (Yield: 0.49 g, Rf: 0.213 min, Condition B, M+H+: 163). EPO
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,872355-63-0, its application will become more common.
Reference:
Patent; SCIOS, INC.; WO2006/112828; (2006); A1;,
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