Adding a certain compound to certain chemical reactions, such as: 94220-38-9, 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, COA of Formula: C7H6ClN3, blongs to pyridine-derivatives compound. COA of Formula: C7H6ClN3
EXAMPLE 4 7-(4-Hydroxyanilino)-5-methyl-1H-pyrazolo[4,3-b]pyridine (E4) STR17 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine (0.5 g, 3 mmol) and 4-aminophenol (0.65 g, 6 mmol) in dry xylene (5 ml) were heated under reflux under nitrogen for 7 h. The resulting solid was collected and washed with water and ethyl acetate, then crystallized from methanol/ethyl acetate to give the hydrochloride salt of the required product (393 mg, 47%), m.p. 308-310 C. (dec.). The hydrochloride salt (355 mg, 1.28 mmol) was dissolved in water (20 ml) and methanol (10 ml) and the solution was adjusted to pH7 with 10% sodium carbonate, to give the title compound as yellow needles (283 mg, 92%), m.p. 174-176 C. (Found: C, 59.30; H, 5.36; N, 21.24. C13 H12 N4 O.1.25.H2 O requires C, 59.42 H, 5.56; N, 21.32).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,94220-38-9, 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine, and friends who are interested can also refer to it.
Reference:
Patent; Beecham Group p.l.c.; US4576952; (1986); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem