Related Products of 944401-77-8, Adding some certain compound to certain chemical reactions, such as: 944401-77-8, name is 2-Amino-4-fluoropyridine,molecular formula is C5H5FN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 944401-77-8.
To a solution of 2-amino-4-fluoropyridine (75.0 g, 0.67 mol) in dry acetonitrile (700 mL), N-bromosuccinimide (122.8 g, 0.69 mol) was added portion wise upon stirring and cooling in an ice-water bath. The reaction mixture was stirred at r.t. for 1 h. After evaporation under reduced pressure, the residue was thoroughly washed with water (3 x 300 mL), taken up by acetonitrile and evaporated under vacuum yielding the title compound as an off white solid (124 g, 97 %).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 944401-77-8, 2-Amino-4-fluoropyridine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; UCB BIOPHARMA SPRL; ALEXANDER, Rikki Peter; BROWN, Julien Alistair; DELIGNY, Michael; HEER, Jag Paul; JACKSON, Victoria Elizabeth; JADOT, Sophie; KROEPLIEN, Boris; MAC COSS, Malcolm; SABNIS, Yogesh Anil; SWINNEN, Dominique Louis Leon; VAN HOUTVIN, Nathalie; ZHU, Zhaoning; WO2015/86527; (2015); A1;,
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