Cai, Hongyun’s team published research in Asian Journal of Organic Chemistry in 2021-10-31 | 55279-29-3

Asian Journal of Organic Chemistry published new progress about [4+2] Cycloaddition reaction. 55279-29-3 belongs to class pyridine-derivatives, and the molecular formula is C6H6N2O, COA of Formula: C6H6N2O.

Cai, Hongyun; Datta Khanal, Hari; Rok Lee, Yong published the artcile< Iodine-Catalyzed Annulations of 2-Amino Carbonyls for Diverse 1-Azaxanthones, Quinolines, and Naphthyridines>, COA of Formula: C6H6N2O, the main research area is amino formylchromone enamine iodine catalyst tandem cycloaddition green chem; azaxanthone preparation; carbonyl aniline enamine iodine catalyst tandem cycloaddition green chem; quinoline preparation; aminonicotinaldehyde enamine iodine catalyst tandem cycloaddition green chem; naphthyridine preparation.

An efficient and facile iodine-catalyzed reaction of 2-amino carbonyls with β-enamino esters or β-enaminones afforded 1-azaxanthones, quinolines and naphthyridines in good to excellent yields. This novel catalytic [4+2] annulation reaction proceeded through a cascade I2-activation, Michael addition, intramol. aldol reaction and aromatization.

Asian Journal of Organic Chemistry published new progress about [4+2] Cycloaddition reaction. 55279-29-3 belongs to class pyridine-derivatives, and the molecular formula is C6H6N2O, COA of Formula: C6H6N2O.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem