Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 72830-09-2, Name is 2-Chloromethyl-3,4-dimethoxypyridinium chloride, molecular formula is , belongs to pyridine-derivatives compound. In a document, author is Wang, Huibo, Product Details of 72830-09-2.
Carbon dots with positive surface charge from tartaric acid and m-aminophenol for selective killing of Gram-positive bacteria
Gram-positive bacteria are one of the most common pathogens causing severe and acute infection, and hospital infection caused by Gram-positive bacteria have increased significantly. Also, as antibiotics have been widely used, abusing of antibiotics is becoming an increasingly serious problem which is followed by dangerous drug resistance. Here, we developed a series of cationic carbon dots (CDs) with high-performance as antibacterial agents by using tartaric acid and m-aminophenol as precursors. The surface charge of these CDs can be regulated from +4.5 +/- 0.42 mV to +33.2 +/- 0.99 mV by increasing the contents of pyridine N and pyrrolic N in CDs. Further antibacterial experiments show that 250 mu g mL(-1) of CDs with +33.2 +/- 0.99 mV can selectively kill Gram-positive bacteria and the antibacterial efficiency can reach approximately >99%. These CDs with positive surface charge can be selectively absorbed on the cell walls of Staphylococcus aureus (S. aureus) via electrostatic interaction and then disturb their physiological metabolism, eventually leading to bacterial death. The present work provides a novel method to adjust the surface charge of CDs and apply these CDs as alternative antibacterial agents.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 72830-09-2, in my other articles. Product Details of 72830-09-2.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem