Category: 100-48-1

COA of Formula: C6H4N2In 2020 ,《A luminescent zinc(II) coordination polymer as a highly selective and sensitive chemosensor for Fe(III) cation and Cr(VI) anions detection in aqueous solution》 appeared in Inorganica Chimica Acta. The author of the article were Li, Ling; Deng, Zhao-Yang; Xie, Xin; Zou, Ji-Yong; You, Sheng-Yong; Chen, Kai-Hong; Le, Jin-Feng. The article conveys some information:

A double-bent-mixed-ligand supported 2-periodic coordination polymer (CP) {[Zn2(FDA)2(4-abpt)2(H2O)2]}n (1) was synthesized from the unique combination of a bent furan-2,5-dicarboxylic acid (H2FDA) ligand and a bent 4-amino-3,5-bis(4-pyridyl)-1,2,4-triazole (4-abpt) coligand. The CP 1 demonstrates readily dispersible two-dimensional (2D) 2-periodic layer structure and considerable chemostability in aqueous media. Luminescence titration experiments indicate that CP 1 can serve as chemosensors for sensitively and selectively detecting Fe3+ cation, CrO42- and Cr2O72- anions in water solution via an environmentally friendly manner. Besides, the luminescent selective quenching mechanism of CP 1 toward Fe3+ cation, CrO42- and Cr2O72- anions is comprehensively studied in the light of absorption of the excitation energy of the host framework by individual analytes. In addition to this study using 4-Cyanopyridine, there are many other studies that have used 4-Cyanopyridine(cas: 100-48-1COA of Formula: C6H4N2) was used in this study.

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.COA of Formula: C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Nanomaterials included an article by Lopez-Tocon, Isabel; Valdivia, Samuel; Soto, Juan; Otero, Juan Carlos; Muniz-Miranda, Francesco; Menziani, Maria Cristina; Muniz-Miranda, Maurizio. Recommanded Product: 100-48-1. The article was titled 《A DFT approach to the surface-enhanced Raman scattering of 4-cyanopyridine adsorbed on silver nanoparticles》. The information in the text is summarized as follows:

A Surface-Enhanced Raman Scattering (SERS) spectrum of 4-cyanopyridine (4CNPy) was recorded on silver plasmonic nanoparticles and analyzed by using D. Functional Theory (DFT) calculations Two simple mol. models of the metal-4CNPy surface complex with a single silver cation or with a neutral dimer (Ag+-4CNPy, Ag2-4CNPy), linked through the two possible interacting sites of 4CNPy (aromatic nitrogen, N, and nitrile group, CN), were considered. The calculated vibrational wavenumbers and intensities of the adsorbate and the isolated species are compared with the exptl. Raman and SERS results. The anal. of the DFT predictions and the exptl. data indicates that 4CNPy adsorbs preferentially on neutral/charged active sites of the silver nanoparticles through the nitrogen atom of the aromatic ring with a perpendicular orientation. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Recommanded Product: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent》 was written by Deng, Zhijie; Zhao, Mingxin; Wang, Feng; Tang, Pingping. Reference of 4-CyanopyridineThis research focused ontrifluoromethoxylated compound preparation regioselective; arene heteroarene trifluoromethyl arylsulfonate trifluoromethoxylation. The article conveys some information:

A general late-stage C-H trifluoromethoxylation of arenes and heteroarenes RH (R = 4-methoxypyridin-2-yl, 4-t-butylphenyl, 3-acetylbenzothien-2-yl, etc.) as limiting reagent with trifluoromethoxide anion was described. The reaction is mediated by silver salts under mild reaction conditions, exhibiting broad substrate scope and wide functional-group compatibility. In addition, ortho-position selective C-H trifluoromethoxylation of pyridines is observed The method is not only applicable to the gram-scale synthesis of trifluoromethoxylated products ROCF3 but also allows efficient late-stage C-H trifluoromethoxylation of marketed small-mol. drugs, common pharmacophores and natural products. In the experimental materials used by the author, we found 4-Cyanopyridine(cas: 100-48-1Reference of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Reference of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Science China: Chemistry included an article by Miao, Meng; Liao, Li-Li; Cao, Guang-Mei; Zhou, Wen-Jun; Yu, Da-Gang. Recommanded Product: 100-48-1. The article was titled 《Visible-light-mediated external-reductant-free reductive cross coupling of benzylammonium salts with (hetero)aryl nitriles》. The information in the text is summarized as follows:

A novel visible-light-mediated external reductant-free reductive cross coupling for the construction of C sp2-C sp3 bonds was reported. A variety of benzylammonium salts RCH(R1)N+(CH3)3O-S(O)2CF3 (R = naphthalen-2-yl, 1-benzothiophen-3-yl, 4-tert-butylphenyl, etc.; R1 = H, Me, n-Pr) and 1,2,3,4-tetrahydro-N,N,N-trimethyl-1-naphthalenaminium 1,1,1-trifluoromethanesulfonate underwent selective coupling with (hetero)aryl nitriles R2CN (R2 = 4-cyano-3-methylphenyl, 2-phenylpyridin-4-yl, isoquinolin-1-yl, etc.) to deliver important diarylmethanes RCH(R1)R2 and 4-(1,2,3,4-tetrahydronaphthalen-1-yl)benzonitrile under mild reaction conditions. Importantly, photocatalysts can be omitted for many cases, which might involve the electron donor acceptor (EDA) complex. Mechanistic studies indicated that benzylic radicals might be involved as the key intermediates. Moreover, the in situ NMe3 generated via cleavage of C-N bond in ammonium salts acts as the electron donor, thus avoiding the use of external-reductant. In the experimental materials used by the author, we found 4-Cyanopyridine(cas: 100-48-1Recommanded Product: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,New Journal of Chemistry included an article by Das, Suman; Bhattacharjee, Jayeeta; Panda, Tarun K.. SDS of cas: 100-48-1. The article was titled 《An imidazolin-2-iminato ligand organozinc complex as a catalyst for hydroboration of organic nitriles》. The information in the text is summarized as follows:

The reaction of diethylzinc with imidazolin-2-imines (ImRNH, R = Dipp (2,6-diisopropylphenyl)), Mes (2,4,6-trimethylphenyl), and tBu (tert-butyl) afforded the corresponding dimeric Zn(II) imidazolin-2-iminato complexes [{(ImRN)ZnEt}2] (R = Dipp, 1a; R = Mes, 1b; R = tBu, 1c). The Zn complexes were characterized using spectroscopic techniques and the mol. structure of complex 1b was established by single-crystal x-ray diffraction anal. Complex 1c was used as a catalyst for the chemoselective hydroboration of organic nitriles with pinacolborane (HBpin) at ambient temperature to obtain diborylamines of a broad substrate scope in high yield. Zn complex 1c exhibits a versatile substrate scope and good functional group tolerance for catalytic hydroboration reactions. A most plausible mechanism is proposed from the kinetic study. In the experiment, the researchers used many compounds, for example, 4-Cyanopyridine(cas: 100-48-1SDS of cas: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.SDS of cas: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Name: 4-CyanopyridineIn 2019 ,《The reductive C3 functionalization of pyridinium and quinolinium salts through iridium-catalysed interrupted transfer hydrogenation》 appeared in Nature Chemistry. The author of the article were Grozavu, Alexandru; Hepburn, Hamish B.; Smith, Philip J.; Potukuchi, Harish K.; Lindsay-Scott, Peter J.; Donohoe, Timothy J.. The article conveys some information:

Aromatic rings are ubiquitous in organic chem. and form the basis of many com. products. Despite the numerous routes available for the preparation of aromatic compounds, there remain few methods that allow their conversion into synthetically useful partially saturated derivatives and even fewer that allow new C-C bonds to be formed at the same time. Here we set out to address this problem and uncover a unique catalytic partial reduction reaction that forms partially saturated azaheterocycles from aromatic precursors. In this reaction, methanol and formaldehyde are used for the reductive functionalization of pyridines and quinolines using catalytic iridium; thus, inexpensive and renewable feedstocks are utilized in the formation of complex N-heterocycles. By harnessing the formation of a nucleophilic enamine intermediate, the C-C bond-forming process reverses the normal pattern of reactivity and allows access to the C3 position of the arene. Mechanistic investigations using D-labeling experiments reveal the source of hydride added to the ring and show the reversible nature of the iridium-hydride addition4-Cyanopyridine(cas: 100-48-1Name: 4-Cyanopyridine) was used in this study.

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Name: 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Nature Communications included an article by Zhu, Shengqing; Qin, Jian; Wang, Fang; Li, Huan; Chu, Lingling. COA of Formula: C6H4N2. The article was titled 《Photoredox-catalyzed branch-selective pyridylation of alkenes for the expedient synthesis of Triprolidine》. The information in the text is summarized as follows:

A catalytic, branch-selective pyridylation of alkenes via a sulfinate assisted photoredox catalysis was reported. This reaction proceeded through a sequential radical addition/coupling/elimination, by utilizing readily available sodium sulfinates as reusable radical precursors as well as traceless elimination groups. This versatile protocol allows for the installation of important vinylpyridines with complete branched selectivity under mild conditions. Furthermore, this catalytic manifold was successfully applied to the expedient synthesis of Triprolidine. In the experiment, the researchers used 4-Cyanopyridine(cas: 100-48-1COA of Formula: C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.COA of Formula: C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Qian, Jianying; Gong, Jinsong; Xu, Zhenghong; Jin, Jian; Shi, Jinsong published an article in 2021. The article was titled 《Significant improvement in conversion efficiency of isonicotinic acid by immobilization of cells via a novel microsphere preparation instrument》, and you may find the article in Bioresource Technology.Safety of 4-Cyanopyridine The information in the text is summarized as follows:

An instrument for the automatic preparation of microspheres was designed and manufactured, and by which cells were immobilized as efficient biocatalyst with small particle diameter, high crosslinking uniformity, and high porosity. The concentration of polymer solution, crosslinking agent and other conditions for preparing the cells microspheres were determined, and the conversion conditions of isonicotinic acid from 4-cyanopyridine were optimized to minimize mass-transfer limitations, and improve thermal and storage stability. The immobilized cells microspheres, which were continuously used for 23 batches, showed a total transformation capacity of 4.6 mol/L 4-cyanopyridine and a cumulative mass of 566.31 g/L of isonicotinic acid, which demonstrated the potential of the durable biocatalyst with efficient conversion capacity. In the part of experimental materials, we found many familiar compounds, such as 4-Cyanopyridine(cas: 100-48-1Safety of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Safety of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《High performance of nitrogen-doped carbon-supported cobalt catalyst for the mild and selective synthesis of primary amines》 was written by Liu, Xixi; Wang, Yanxin; Jin, Shiwei; Li, Xun; Zhang, Zehui. Recommanded Product: 100-48-1 And the article was included in Arabian Journal of Chemistry in 2020. The article conveys some information:

A nitrogen-doped carbon-supported Co catalyst (Co/N-C-800) was discovered to be highly active for the reductive amination of carbonyl compounds with NH3 and the hydrogenation of nitriles into primary amines using H2 as the hydrogen source. Structurally diverse carbonyl compounds were selectively transformed into primary amines with good to excellent yields (82.8-99.6%) under mild conditions. The Co/N-C-800 catalyst showed comparable or better catalytic performance than the reported noble metal catalysts. The Co/N-C-800 catalyst also showed high activity for the hydrogenation of nitriles, affording the corresponding primary amines with high yields (81.7-99.0%). An overall reaction mechanism is proposed for the reductive amination of benzaldehyde and the hydrogenation of benzonitrile, which involves the same intermediates of phenylmethanimine and N-benzylidenebenzylamine. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Recommanded Product: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Recommanded Product: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Structural Variety in Mn(NCS)2 4-Cyanopyridine Coordination Compounds: Synthesis, Structures, Isomerism, and Magnetic Properties》 was written by Wellm, Carsten; Neumann, Tristan; Gallo, Gianpiero; Dziubyna, Anna M.; Rams, Michal; Dinnebier, Robert E.; Naether, Christian. Quality Control of 4-Cyanopyridine And the article was included in Crystal Growth & Design in 2020. The article conveys some information:

The reaction of Mn(NCS)2 with 4-cyanopyridine (CNpy) gives discrete complexes [Mn(NCS)2(CNpy)4] (1), [Mn(NCS)2(H2O)2(CNpy)2] (2-I and 2-II), and [Mn(NCS)2(H2O)2(CNpy)2]·xCNpy (x = 4, 3; x = 2, 4), in which the Mn(II) centers are octahedrally coordinated by two terminal N-bonded thiocyanate anions and by four (1) or two CNpy coligands and two H2O mols. (2-I, 2-II, 3, and 4). If an excess of Mn(NCS)2 was used, [Mn(NCS)2(CNpy)2]n (5) and [Mn(NCS)2(CNpy)]n (6-I and 6-II) were obtained. In all compounds the Mn(II) cations are octahedrally coordinated and linked into linear chains (5), into layers (6-I), or into a 3-dimensional network (6-II) by the thiocyanate anions. Studies using TG-DTA and temperature-dependent powder x-ray diffraction prove that the discrete complexes 2-II, 3, and 4 decompose in several steps, giving Mn(NCS)2 via 5 and 6-I as intermediates. For compounds 2-II, 4, and 6-II only one batch was obtained, indicating that these compounds are metastable. Magnetic measurements for 5 and 6-I reveal dominating antiferromagnetic interactions and susceptibility curve maxima at 20 K (5) and 24 K (6-I), reproduced by quantum Monte Carlo simulations. The sp. heat proves magnetic ordering at 2.8 K (5) and 12.4 K (6-I). The ordering of 6-I is associated with a weak ferromagnetism. Several Mn(NCS)2 4-cyanopyridine coordination compounds including polymorphic and isomeric modifications were synthesized and structurally characterized by SC-XRD and PXRD. Their thermal reactivity and magnetic behavior were studied. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Quality Control of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Quality Control of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem