Category: 100-48-1

In 2022,Yang, Yu-Ting; Tu, Chang-Zheng; Shi, Jun-You; Yang, Xiao-Li; Liu, Jian-Jun; Cheng, Fei-Xiang published an article in Journal of Solid State Chemistry. The title of the article was 《Cu(I)-organic framework as a platform for high-efficiency selective adsorption of methylene blue and reversible iodine uptake》.Safety of 4-Cyanopyridine The author mentioned the following in the article:

A Cu(I)-MOF, {[Cu(4-PTZ)]·(H2O)0.5}n (1), that contains rhombic channels with the size of 10.174 Å x 16.965 Å was obtained based on in situ generated 5-(4-pyridyl)-1H-tetrazole ligand (4-HPTZ). Compound 1 not only displays remarkable capability for selective adsorption toward the organic dye Methylene Blue (149.5 mg g-1), but also shows reversible adsorption of I2 mols. in hexane medium (96.2%). Therefore, compound 1 should be a promising MOF-based bifunctional adsorbent in the field of pollutant removal. In the experiment, the researchers used many compounds, for example, 4-Cyanopyridine(cas: 100-48-1Safety of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Safety of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Category: pyridine-derivativesIn 2019 ,《Dehydrogenative Synthesis of Quinolines, 2-Aminoquinolines, and Quinazolines Using Singlet Diradical Ni(II)-Catalysts》 appeared in Journal of Organic Chemistry. The author of the article were Chakraborty, Gargi; Sikari, Rina; Das, Siuli; Mondal, Rakesh; Sinha, Suman; Banerjee, Seemika; Paul, Nanda D.. The article conveys some information:

Simple, straightforward, and atom economic methods for the synthesis of quinolines, 2-aminoquinolines, and quinazolines via biomimetic dehydrogenative condensation/coupling reactions, catalyzed by well-defined inexpensive and easy to prepare singlet diradical Ni(II)-catalysts featuring two antiferromagnetically coupled singlet diradical diamine type ligands are described. Various polysubstituted quinolines, 2-aminoquinolines, and quinazolines were synthesized in moderate to good yields from different low-cost and readily accessible starting materials. Several control experiments were carried out to get insight into the reaction mechanism which shows that the nickel and the coordinated diamine ligands participate in a synergistic way during the dehydrogenation of alcs. In the experiment, the researchers used many compounds, for example, 4-Cyanopyridine(cas: 100-48-1Category: pyridine-derivatives)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Electron-Donating Effect Enabled Simultaneous Improvement on the Mechanical and Self-Healing Properties of Bromobutyl Rubber Ionomers》 was written by Zhang, Linjun; Wang, Hao; Zhu, Yong; Xiong, Hui; Wu, Qi; Gu, Shiyu; Liu, Xikui; Huang, Guangsu; Wu, Jinrong. Name: 4-Cyanopyridine And the article was included in ACS Applied Materials & Interfaces in 2020. The article conveys some information:

Due to the dynamic nature of networks and high mobility of mol. chains, self-healing elastomers are usually confronted with the trade-off between self-healing efficiency and mech. properties. Herein, a self-healing ionomer with both high mech. performance and high self-healing efficiency has been successfully developed by grafting bromobutyl rubber (BIIR) with pyridine-based derivatives Interestingly, the substituents on the pyridine ring can be used to regulate the interaction forces of ionic clusters and mol. dynamics. The electron-donating effect of the substituents facilitates stable π-π stacking between pyridyl ions, inducing the formation of regular and large ion aggregates, thereby improving the mech. strength of the ionomer. Meanwhile, the plasticizing effect of the substituents reduces the activation energy and relaxation temperature of the ionic aggregates, thus endowing the ionomer with a high self-healing efficiency. As a result, the ionomer shows tensile strength as high as 8.1 ± 0.3 MPa under room temperature and self-healing efficiency of 100 ± 3% at 60°C. Therefore, this strategy can be easily extended to other halogen-containing polymers, leading to a novel class of self-healing ionomers that hold great promise in diverse applications. In addition to this study using 4-Cyanopyridine, there are many other studies that have used 4-Cyanopyridine(cas: 100-48-1Name: 4-Cyanopyridine) was used in this study.

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Name: 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Electron-Donating Effect Enabled Simultaneous Improvement on the Mechanical and Self-Healing Properties of Bromobutyl Rubber Ionomers》 was written by Zhang, Linjun; Wang, Hao; Zhu, Yong; Xiong, Hui; Wu, Qi; Gu, Shiyu; Liu, Xikui; Huang, Guangsu; Wu, Jinrong. Name: 4-Cyanopyridine And the article was included in ACS Applied Materials & Interfaces in 2020. The article conveys some information:

Due to the dynamic nature of networks and high mobility of mol. chains, self-healing elastomers are usually confronted with the trade-off between self-healing efficiency and mech. properties. Herein, a self-healing ionomer with both high mech. performance and high self-healing efficiency has been successfully developed by grafting bromobutyl rubber (BIIR) with pyridine-based derivatives Interestingly, the substituents on the pyridine ring can be used to regulate the interaction forces of ionic clusters and mol. dynamics. The electron-donating effect of the substituents facilitates stable π-π stacking between pyridyl ions, inducing the formation of regular and large ion aggregates, thereby improving the mech. strength of the ionomer. Meanwhile, the plasticizing effect of the substituents reduces the activation energy and relaxation temperature of the ionic aggregates, thus endowing the ionomer with a high self-healing efficiency. As a result, the ionomer shows tensile strength as high as 8.1 ± 0.3 MPa under room temperature and self-healing efficiency of 100 ± 3% at 60°C. Therefore, this strategy can be easily extended to other halogen-containing polymers, leading to a novel class of self-healing ionomers that hold great promise in diverse applications. In addition to this study using 4-Cyanopyridine, there are many other studies that have used 4-Cyanopyridine(cas: 100-48-1Name: 4-Cyanopyridine) was used in this study.

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Name: 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Oxidative ammonolysis of β- and γ-picoline on modified vanadium-titanium oxide catalysts》 was written by Vorobyev, P. B.; Mikhailovskaya, T. P.; Kadirbekov, K. A.; Kurmakyzy, R.. Application of 100-48-1This research focused onvanadium titanium chromium tin iron oxide oxidative ammonolysis catalyst; nicotinonitrile isonicotinonitrile preparation; selectivity vanadium titanium oxide catalyst oxidative ammonolysis picoline. The article conveys some information:

The modifying effect of chromium (III), tin (IV) and iron (III) oxide additives to the binary V-Ti-oxide system in the reaction of oxidative ammonolysis of β- and γ-picolines was investigated. Relation of the studied oxide systems catalytic activity on the calculated values of proton affinity for the vanadyl oxygen of their surface, which is involved in the deprotonation of Me substituents converted to a nitrile group, has been established. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanopyridine(cas: 100-48-1Application of 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Application of 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of 4-CyanopyridineIn 2020 ,《Arene-ruthenium(II)-phosphine complexes: Green catalysts for hydration of nitriles under mild conditions》 was published in Inorganic Chemistry Communications. The article was written by Vyas, Komal M.; Mandal, Poulami; Singh, Rinky; Mobin, Shaikh M.; Mukhopadhyay, Suman. The article contains the following contents:

Three new arene-ruthenium(II) complexes were prepared by treating [{RuCl(μ-Cl)(η6-arene)}2] (η6-arene = p-cymene) dimer with tri(2-furyl)phosphine (PFu3) and 1,3,5-triaza-7-phosphaadamantane (PTA), resp. to obtain [RuCl2(η6-arene)PFu3] [Ru]-1, [RuCl(η6-arene)(PFu3)(PTA)]BF4 [Ru]-2 and [RuCl(η6-arene)(PFu3)2]BF4 [Ru]-3. All the complexes were structurally identified using anal. and spectroscopic methods including single-crystal X-ray studies. The effectiveness of resulting complexes as potential homogeneous catalysts for selective hydration of different nitriles into corresponding amides in aqueous medium and air atm. was explored. There was a remarkable difference in catalytic activity of the catalysts depending on the nature and number of phosphorus-donor ligands and sites available for catalysis. Exptl. studies performed using structural analogs of efficient catalyst concluded a structural-activity relationship for the higher catalytic activity of [Ru]-1, being able to convert huge variety of aromatic, heteroaromatic and aliphatic nitriles. The use of eco-friendly water as a solvent, open atm. and avoidance of any organic solvent during the catalytic reactions prove the reported process to be truly green and sustainable. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Reference of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Reference of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《New Radical Borylation Pathways for Organoboron Synthesis Enabled by Photoredox Catalysis》 was written by Qi, Jing; Zhang, Feng-Lian; Jin, Ji-Kang; Zhao, Qiang; Li, Bin; Liu, Lin-Xuan; Wang, Yi-Feng. Safety of 4-Cyanopyridine And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

Radical borylation using N-heterocyclic carbene (NHC)-BH3 complexes as boryl radical precursors has emerged as an important synthetic tool for organoboron assembly. However, the majority of reported methods are limited to reaction modes involving carbo- and/or hydroboration of specific alkenes and alkynes. Moreover, the generation of NHC-boryl radicals relies principally on hydrogen atom abstraction with the aid of radical initiators. A distinct radical generation method is reported, as well as the reaction pathways of NHC-boryl radicals enabled by photoredox catalysis. NHC-boryl radicals are generated via a single-electron oxidation and subsequently undergo cross-coupling with the in-situ-generated radical anions to yield gem-difluoroallylboronates. A photoredox-catalyzed radical arylboration reaction of alkenes was achieved using cyanoarenes as arylating components from which elaborated organoborons were accessed. Mechanistic studies verified the oxidative formation of NHC-boryl radicals through a single-electron-transfer pathway.4-Cyanopyridine(cas: 100-48-1Safety of 4-Cyanopyridine) was used in this study.

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Safety of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Metal-Free, Redox-Neutral, Site-Selective Access to Heteroarylamine via Direct Radical-Radical Cross-Coupling Powered by Visible Light Photocatalysis》 was written by Zhou, Chao; Lei, Tao; Wei, Xiang-Zhu; Ye, Chen; Liu, Zan; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu. Safety of 4-Cyanopyridine And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

Transition-metal-catalyzed C-N bond-forming reactions have emerged as fundamental and powerful tools to construct arylamines, a common structure found in drug agents, natural products, and fine chems. Reported herein is an alternative access to heteroarylamine via radical-radical cross-coupling pathway, powered by visible light catalysis without any aid of external oxidant and reductant. Only by visible light irradiation of a photocatalyst, such as a metal-free photocatalyst, does the cascade single-electron transfer event for amines and heteroaryl nitriles occur, demonstrated by steady-state and transient spectroscopic studies, resulting in an amine radical cation and aryl radical anion in situ for C-N bond formation. The metal-free and redox economic nature, high efficiency, and site-selectivity of C-N cross-coupling of a range of available amines, hydroxylamines, and hydrazines with heteroaryl nitriles make this protocol promising in both academic and industrial settings. In the experiment, the researchers used many compounds, for example, 4-Cyanopyridine(cas: 100-48-1Safety of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Safety of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Australian Journal of Chemistry included an article by Wegeberg, Christina; Nielsen, David; Mossin, Susanne; Abrahams, Brendan F.; McKee, Vickie; McKenzie, Christine J.. SDS of cas: 100-48-1. The article was titled 《Reversible and Vapochromic Chemisorption of Ammonia by a Copper(II) Coordination Polymer》. The information in the text is summarized as follows:

The single crystal x-ray structure determination of {[Cu(tpt)(o-phthalate)]·3 1/3(C2H2Cl4)}n (tpt = 2,4,6-tri-4-pyridyl-1,3,5-triazine, C2H2Cl4 = 1,1,2,2-tetrachloroethane = TCE) shows a 3-dimensional network in which Cu centers are linked by 3-connecting tpt ligands with the topol. of a 12,3 net. Cu centers are further linked by o-phthalate dianions. The copper coordination geometry is square pyramidal, with o-phthalate oxygen donors trans to each other in the basal plane and the remaining positions taken by the pyridines of three linking tpt units. The solvent accessible void space is ∼65%. The pale blue-green crystalline desolvate, obtained by heating to 200° or washing the TCE solvate with acetone is [Cu(tpt)(o-phthalate)]n. Powder x-ray diffraction and ESR spectroscopy show that the crystal structure and the Cu geometry changes upon desolvation. The crystalline desolvated phase sorbs two equivalent of ammonia per copper ion. The adduct, mauve [Cu(tpt)(o-phthalate)(NH3)2]n, shows reasonable crystallinity and is stable up to ∼150° under ambient conditions before the reversible desorption (min. 10 cycles) of the guest ammonia. The color change and high desorption temperature, along with changes in g values, is suggestive of chemisorption in two steps with Cu-ammine bonding in the loaded phase. In the experimental materials used by the author, we found 4-Cyanopyridine(cas: 100-48-1SDS of cas: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. SDS of cas: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhang, Lei; Pfund, Bjorn; Wenger, Oliver S.; Hu, Xile published an article in 2022. The article was titled 《Oxidase-Type C-H/C-H Coupling Using an Isoquinoline-Derived Organic Photocatalyst》, and you may find the article in Angewandte Chemie, International Edition.Name: 4-Cyanopyridine The information in the text is summarized as follows:

Herein, an isoquinoline-derived diaryl ketone-type photocatalyst I, which has much enhanced absorption of blue and visible light compared to conventional diaryl ketones was reported. This photocatalyst enables dehydrogenative cross-coupling of heteroarenes e.g., II with inactivated and activated alkanes viz. cyclohexane, THF, adamantane, etc. as well as aldehydes viz. propanal, pentanal, 3-methylbutanal, cyclopropanecarbaldehyde, cyclopentanecarbaldehyde using air as the oxidant. A wide range of heterocycles with various functional groups are suitable substrates. Transient absorption and excited-state quenching experiments point to an unconventional mechanism that involves an excited state ”self-quenching” process to generate the N-radical cation form of the sensitizer, which subsequently abstracts a hydrogen atom from the alkane substrate to yield a reactive alkyl radical. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Name: 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Name: 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem