Electric Literature of 1010422-51-1, Adding some certain compound to certain chemical reactions, such as: 1010422-51-1, name is 5-Bromo-4-methyl-2-(trifluoromethyl)pyridine,molecular formula is C7H5BrF3N, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1010422-51-1.
A mixture of 5-bromo-4-methyl-2-(trifluoromethyl)pyridine (150 mg, 625 mumol), bis(pinacolato)diboron (189 mg, 729 mumol), Pd(dppf)Cl2 (89 mg, 106 mumol) and potassium acetate (120 mg, 1.25 mmol) in dioxane (1 mL) was stirred under N2 at 90 C. overnight. Aqueous NH4Cl was added and the mixture was extracted with CH2Cl2. The combined organic layers were dried and the volatiles were removed under reduced pressure to yield the desired compound which was used in the next step without further purification.
According to the analysis of related databases, 1010422-51-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GRUeNENTHAL GMBH; VOSS, FELIX; NORDHOFF, SONJA; WACHTEN, SEBASTIAN; WELBERS, ANDRE; RITTER, STEFANIE; US2015/166505; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem