Category: 103-74-2

In 2018,Manojveer, Seetharaman; Forrest, Sebastian J. K.; Johnson, Magnus T. published 《Ru-Catalyzed Completely Deoxygenative Coupling of 2-Arylethanols through Base-Induced Net Decarbonylation》.Chemistry – A European Journal published the findings.Recommanded Product: 2-(2-Hydroxyethyl)pyridine The information in the text is summarized as follows:

Substituted arylethanols can be coupled by using a readily available Ru catalyst in a fully deoxygenative manner to produce hydrocarbon chains in one step. Control experiments indicate that the first deoxygenation occurs through an aldol condensation, whereas the second occurs through a base-induced net decarbonylation. This double deoxygenation enables further development in the use of alcs. as versatile and green alkylating reagents, as well as in other fields, such as deoxygenation and upgrading of overfunctionalized biomass to produce hydrocarbons. In the experimental materials used by the author, we found 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Recommanded Product: 2-(2-Hydroxyethyl)pyridine)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: 2-(2-Hydroxyethyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Recommanded Product: 2-(2-Hydroxyethyl)pyridineIn 2018 ,《Coordination Chemistry of N-(2-Pyridylethyl)-Substituted Bulky Amidinates and Triazenides of Magnesium》 appeared in European Journal of Inorganic Chemistry. The author of the article were Kalden, Diana; Krieck, Sven; Goerls, Helmar; Westerhausen, Matthias. The article conveys some information:

The amidines Dipp-N:C(R)-NH(C2H4R’) [R = tBu, R’ = Ph (1a); R = Ph, R’ = Py (1b)] as well as 1-(2,4,6-triisopropylphenyl)-3-(2-pyridylethyl)triazene (1c) are magnesiated with com. available dibutylmagnesium yielding the complexes [(THF)Mg{Dipp-N:C(tBu)-N(C2H4Ph)}2] (3a), [Mg{Dipp-N:C(Ph)-N(C2H4Py)}2] (3b), and [Mg{Tripp-N:N-N(C2H4Py)}2] (3c). Handling and isolation of triazene 1c has been performed at room temperature or below to avoid elimination of dinitrogen and formation of 2-pyridylethyl-(2,4,6-triisopropylphenyl)amine (2). In the solid state, the compounds 1b and 1c form dimers via intermol. hydrogen bridges to the pyridyl groups of neighboring mols. The results came from multiple reactions, including the reaction of 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Recommanded Product: 2-(2-Hydroxyethyl)pyridine)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Recommanded Product: 2-(2-Hydroxyethyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Oxadiazole-functionalized fibers for selective adsorption of Hg2+》 was written by Du, Huimin; Xie, Yujia; Zhang, Haonan; Chima, Anyaegbu; Tao, Minli; Zhang, Wenqin. Recommanded Product: 103-74-2 And the article was included in Industrial & Engineering Chemistry Research in 2020. The article conveys some information:

Six kinds of 1,3,4-oxadiazole-functionalized fibers were prepared to evaluate the adsorption capacity for Hg2+. Finally, a functionalized fiber (PANp-PMODF) with the best adsorption performance was selected for further research. The PANp-PMODF fiber was characterized by IR (IR), elemental anal. (EA), SEM (SEM), X-ray diffraction (XRD), and XPS. The PANp-PMODF shows excellent selectivity for mercury ions in a mixed heavy metal ion solution (Hg2+, Ni2+, Pb2+, Zn2+, Ag+, Co2+, Cr3+, Cu2+, and Cd2+), and it can reduce the concentration of Hg2+ to 44 ppb in the actual sewage, which is of great practical value for the treatment of mercury pollution. Furthermore, the adsorbed Hg2+ can be desorbed completely by dilute HNO3 and the PANp-PMODF can be reused many times with excellent recyclability. In the experiment, the researchers used many compounds, for example, 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Recommanded Product: 103-74-2)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Recommanded Product: 103-74-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Afsharnadery, Fatemeh; Khosravi, Kaveh; Zolfigol, Mohammad Ali published their research in Applied Organometallic Chemistry in 2021. The article was titled 《A novel magnetically recyclable semi-dendrimer catalyst-based ethanolpyridole supported on ferrite nanoparticles (HNPs@Py) for the synthesis of biscoumarin and dihydropyrano[3,2-c]chromene derivatives》.Synthetic Route of C7H9NO The article contains the following contents:

The novel organic-inorganic nanohybrid magnetic nanoparticles (HNPs@Py) were prepared by a simple method and characterized by FT-IR, XRD, FE-SEM, TGA, VSM, EDX, and MAP. The catalytic activity of this new (HNPs@Py) was studied for green synthesis of biscoumarins I (R = 4-Br, 3-NO2, 2-OH, etc.) and 3,4-dihydropyrano[c]chromene derivatives II (Ar = 2,4-dichlorophenyl, naphthalen-2-yl, 3-hydroxyphenyl). The short reaction time, high yields, simple workup, and easy separation of catalyst from the reaction mixture by an external magnetic field are the main advantages of the present protocol. In the experiment, the researchers used 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Synthetic Route of C7H9NO)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Synthetic Route of C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Angewandte Chemie, International Edition included an article by Yang, Zhongming; Zhao, Weijia; Liu, Wei; Wei, Xing; Chen, Meng; Zhang, Xiao; Zhang, Xiaolei; Liang, Yong; Lu, Changsheng; Yan, Hong. Computed Properties of C7H9NO. The article was titled 《Metal-Free Oxidative B-N Coupling of nido-Carborane with N-Heterocycles》. The information in the text is summarized as follows:

A general method for the oxidative substitution of nido-carborane (7,8-C2B9H12-) with N-heterocycles has been developed by using 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) as an oxidant, producing 9-Het-7,8-R2-7,8-dicarbaundecaboranes(11) [Het = pyridine, (iso)quinoline, (benz)imidazole, (benzo)thiazole, oxazole, pyrazole, pyrimidine 6-azaindole; R = Ph, H, Me, tBu, RR = CH2CH:CHCH2]. This metal-free B-N coupling strategy, in both inter- and intramol. fashions, gave rise to a wide array of charge-compensated, boron-substituted nido-carboranes in high yields (up to 97%) with excellent functional-group tolerance under mild reaction conditions. The reaction mechanism was investigated by d.-functional theory (DFT) calculations A successive single-electron transfer (SET), B-H hydrogen-atom transfer (HAT), and nucleophilic attack pathway is proposed. This method provides a new approach to nitrogen-containing carboranes with potential applications in medicine and materials. In the part of experimental materials, we found many familiar compounds, such as 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Computed Properties of C7H9NO)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Computed Properties of C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lai, Miao; Su, Fangyao; Hu, Jingyi; Wang, Mengzhuo; Zhao, Mingqin; Zhang, Ganlin published an article in 2021. The article was titled 《Synthesis of N-heteroarenemethyl esters via C-C bond cleavage of acyl cyanides under transition metal-free conditions》, and you may find the article in Frontiers in Chemistry (Lausanne, Switzerland).Quality Control of 2-(2-Hydroxyethyl)pyridine The information in the text is summarized as follows:

A practical method to synthesize N-heteroaryl esters from N-heteroaryl methanols with acyl cyanides via C-C bond cleavage without using any transition metal is demonstrated here. The use of Na2CO3/15-crown-5 couple enables access to a series of N-heteroaryl esters in high efficiency. This protocol is operationally simple and highly environmentally benign producing only cyanides as byproducts. The results came from multiple reactions, including the reaction of 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Quality Control of 2-(2-Hydroxyethyl)pyridine)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Quality Control of 2-(2-Hydroxyethyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2017,Wappes, Ethan A.; Nakafuku, Kohki M.; Nagib, David A. published 《Directed β C-H Amination of Alcohols via Radical Relay Chaperones》.Journal of the American Chemical Society published the findings.Recommanded Product: 103-74-2 The information in the text is summarized as follows:

A radical-mediated strategy for β C-H amination of alcs. has been developed. This approach employs a radical relay chaperone, which serves as a traceless director that facilitates selective C-H functionalization via 1,5-hydrogen atom transfer (HAT) and enables net incorporation of ammonia at the β carbon of alcs. The chaperones presented herein enable direct access to imidate radicals, allowing their first use for H atom abstraction. A streamlined protocol enables rapid conversion of alcs. to their β-amino analogs (via in situ conversion of alcs. to imidates, directed C-H amination, and hydrolysis to NH2). Mechanistic experiments indicate HAT is rate-limiting, whereas intramol. amination is product- and stereo-determining In addition to this study using 2-(2-Hydroxyethyl)pyridine, there are many other studies that have used 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Recommanded Product: 103-74-2) was used in this study.

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 103-74-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Colgan, Avene C.; Proctor, Rupert S. J.; Gibson, David C.; Chuentragool, Padon; Lahdenpera, Antti S. K.; Ermanis, Kristaps; Phipps, Robert J. published an article in Angewandte Chemie, International Edition. The title of the article was 《Hydrogen Atom Transfer Driven Enantioselective Minisci Reaction of Alcohols》.Electric Literature of C7H9NO The author mentioned the following in the article:

Catalytic enantioselective Minisci reactions have recently been developed but all instances so far utilize α-amino radical coupling partners. Authors report a substantial evolution of the enantioselective Minisci reaction that enables α-hydroxy radicals to be used, providing valuable enantioenriched secondary alc. products. This is achieved through the direct oxidative coupling of two C-H bonds on simple alc. and pyridine partners through a hydrogen atom transfer (HAT)-driven approach: a challenging process to achieve due to the numerous side reactions that can occur. This approach is highly regioselective as well as highly enantioselective. Dicumyl peroxide, upon irradiation with 390 nm light, serves as both HAT reagent and oxidant while selectivity is controlled by use of a chiral phosphoric acid catalyst. Computational and exptl. evidence provide mechanistic insight as to the origin of selectivity, revealing a stereodetermining deprotonation step distinct from the analogous reaction of amide-containing substrates. The experimental part of the paper was very detailed, including the reaction process of 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Electric Literature of C7H9NO)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Electric Literature of C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rajesh, Sarigama; Zhai, Jiali; Drummond, Calum J.; Tran, Nhiem published an article in 2021. The article was titled 《Synthetic ionizable aminolipids induce a pH dependent inverse hexagonal to bicontinuous cubic lyotropic liquid crystalline phase transition in monoolein nanoparticles》, and you may find the article in Journal of Colloid and Interface Science.Recommanded Product: 2-(2-Hydroxyethyl)pyridine The information in the text is summarized as follows:

A prospective class of materials for drug delivery is lyotropic liquid crystalline (LLC) nanoparticles, such as cubosomes and hexosomes. Efforts are being made to generate a pH dependent system, which exhibits slow release hexosomes (H2) at physiol. pH and relatively fast release cubosomes (Q2) at acidic disease sites such as in various cancers and bacterial infection (pH ∼ 5.5-6.5). Herein, we report the synthesis of nine ionizable aminolipids, which were doped into monoolein (MO) lipid nanoparticles. Using high throughput formulation and synchrotron small angle X-ray scattering (SAXS), the effects of aminolipid structure and concentration on the mesophase of MO nanoparticles at various pHs were determined As the pH changed from neutral to acidic, mesophases, could be formed in an order L2 (inverse micelles) → H2 → Q2. Specifically, systems with heterocyclic oleates exhibited the H2 to Q2 transition at pH 5.5-6.5. Furthermore, the phase transition pH could be fine-tuned by incorporating two aminolipids into the nanoparticles. Nanoparticles with a pH dependent phase transition as described in this study may be useful as drug delivery carriers for the treatment of cancers and certain bacterial infection. In the experiment, the researchers used many compounds, for example, 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Recommanded Product: 2-(2-Hydroxyethyl)pyridine)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 2-(2-Hydroxyethyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Matsuoka, Keitaro; Komami, Narumi; Kojima, Masahiro; Mita, Tsuyoshi; Suzuki, Kimichi; Maeda, Satoshi; Yoshino, Tatsuhiko; Matsunaga, Shigeki published their research in Journal of the American Chemical Society in 2021. The article was titled 《Chemoselective Cleavage of Si-C(sp3) Bonds in Unactivated Tetraalkylsilanes Using Iodine Tris(trifluoroacetate)》.Formula: C7H9NO The article contains the following contents:

Herein chemoselective cleavage of Si-C(sp3) bonds of unactivated tetraalkylsilanes was reported using iodine tris(trifluoroacetate). The reaction proceeded smoothly under mild conditions (-50°C to room temperature) and tolerated various polar functional groups, thus enabling subsequent Tamao-Fleming oxidation to provide the corresponding alcs. NMR experiments and d. functional theory calculations on the reaction indicated that the transfer of alkyl groups from Si to the I(III) center and the formation of the Si-O bond proceed concertedly to afford an alkyl-λ3-iodane and silyl trifluoroacetate. The developed method enabled the use of unactivated tetraalkylsilanes as highly stable synthetic precursors. In the part of experimental materials, we found many familiar compounds, such as 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Formula: C7H9NO)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Formula: C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem