Category: 107263-95-6

Lopez-Alvarado, Pilar published the artcileA general synthesis of quinoline-2,5,8(1H)-triones via acylation of 2,5-dimethoxyaniline with S-tert-butyl thioacetates by application of the Knorr cyclization, Synthetic Route of 107263-95-6, the publication is Synthesis (1998), 186-194, database is CAplus.

An efficient synthesis of 3- and/or 4-alkylated quinoline-2,5,8(1H)-triones is described. The reaction sequence employed involves Knorr cyclization of 2,5-dimethoxyanilides into 5,8-dimethoxyquinoline systems, followed by oxidative demethylation with (NH₄)₂Ce(NO₃)₆. The starting 2,5-dimethoxyanilides were prepared by chemoselective acylation of 2,5-(MeO)₂C₆H₃NH₂ with a series of β-oxo thioesters obtained by regioselective alkylation of AcCH₂C(O)SCMe₃ at C(2) and/or C(4). The introduction of electrophiles other than alkyl groups at C(2) on AcCH₂C(O)SCMe₃ was also studied.

Synthesis published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, Synthetic Route of 107263-95-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Rozatian, Neshat published the artcileA quantitative reactivity scale for electrophilic fluorinating reagents, Related Products of pyridine-derivatives, the publication is Chemical Science (2018), 9(46), 8692-8702, database is CAplus and MEDLINE.

The N-F reagent was currently determined through empirical experimentation in the absence of quant. values for electrophilicities. An exptl.-determined kinetic reactivity scale for ten N-F fluorinating reagents, including Selectfluor, NFSI, Synfluor and several N-fluoropyridinium salts, in CH₃CN ws reported. The reactivity scale, which covers eight orders of magnitude, employs para-substituted 1,3-diaryl-1,3-dicarbonyl derivatives to measure relative and absolute rate constants The para-substituted 1,3-diaryl-1,3-dicarbonyl scaffold delivers a convenient, sensitive spectrophotometric reporter of reactivity that also led to the discovery of a unique form of tautomeric polymorphism.

Chemical Science published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Shigehisa, Hiroki published the artcileHydroalkoxylation of Unactivated Olefins with Carbon Radicals and Carbocation Species as Key Intermediates, Application In Synthesis of 107263-95-6, the publication is Journal of the American Chemical Society (2013), 135(28), 10306-10309, database is CAplus and MEDLINE.

A unique Markovnikov hydroalkoxylation of unactivated olefins with a cobalt complex, silane, and N-fluoropyridinium salt is reported. Further optimization of reaction conditions yielded high functional group tolerance and versatility of alc. solvent employed, including methanol, i-propanol, and t-butanol. Use of trifluorotoluene as a solvent made the use of alc. in stoichiometric amount possible. Mechanistic insight into this novel catalytic system is also discussed. Exptl. results suggest that catalysis involves both carbon radical and carbocation intermediates.

Journal of the American Chemical Society published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C8H17Br, Application In Synthesis of 107263-95-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem