Category: 1075-62-3

Asadujjaman, Asad et al. published their research in Polymer Chemistry in 2017 | CAS: 1075-62-3

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application of 1075-62-3

Thermoresponsive functional polymers based on 2,6-diaminopyridine motif with tunable UCST behaviour in water/alcohol mixtures was written by Asadujjaman, Asad;Ahmadi, Vahid;Yalcin, Meral;ten Brummelhuis, Niels;Bertin, Annabelle. And the article was included in Polymer Chemistry in 2017.Application of 1075-62-3 This article mentions the following:

2,6-Diaminopyridine based functional polymers poly(N-(6-aminopyridin-2-yl)acrylamide) (PNAPAAm) and poly(N-(6-acetamidopyridin-2-yl)acrylamide) (PNAcAPAAm) were synthesized via free radical polymerization and in addition PNAcAPAAm was synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization for comparison. The obtained polymers displayed upper critical solution temperature (UCST)-type reversible thermoresponsiveness in water/alc. mixtures The UCST phase transition behavior of the obtained functional polymers was studied using temperature dependent turbidimetry, dynamic light scattering and 1H-NMR measurements. The phase transition temperature of the polymers was tunable by varying either the concentration of the polymer solution, the nature of the alc. or the composition of the solvent mixture The cloud point temperature of PNAcAPAAm was found to decrease with increasing alc. content (MeOH, EtOH and iPrOH) in water/alc. mixtures Past a critical amount of EtOH or iso-PrOH in water, the cloud point temperature of PNAcAPAAm increased upon further addition of EtOH or iso-PrOH. Such functional polymers with tunable UCST behavior can be applicable in drug delivery, sensing, personal care and microfluidic applications. In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3Application of 1075-62-3).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application of 1075-62-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Huang, Cheng-Wei et al. published their research in Macromolecules (Washington, DC, United States) in 2016 | CAS: 1075-62-3

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 1075-62-3

Functional Supramolecular Polypeptides Involving π-π Stacking and Strong Hydrogen-Bonding Interactions: A Conformation Study toward Carbon Nanotubes (CNTs) Dispersion was written by Huang, Cheng-Wei;Mohamed, Mohamed Gamal;Zhu, Chao-Yuan;Kuo, Shiao-Wei. And the article was included in Macromolecules (Washington, DC, United States) in 2016.Recommanded Product: 1075-62-3 This article mentions the following:

New supramol. polypeptides have been prepared through simple ring-opening polymerization and “click” reactions. Postfunctionalization with diaminopyridine (DAP) moieties, capable of multiple hydrogen bonding, was an efficient approach toward forming α-helical-dominant polypeptides. The phys. crosslinked networks produced upon self-organization of the DAP units increased the glass transition temperature (Tg) of the polymers and sustained the secondary structures of the polypeptides. Addnl. thermal responsivity resulted from dynamic noncovalent bonding on the polymer side chains. Mol. recognition through heterocomplementary DAP···thymine (T) base pairs was revealed spectroscopically and then used to construct poly(γ-propargyl-L-glutamate)-g-N-(6-acetamidopyridin-2-yl)-11-undecanamide/thyminylpyrene (PPLG-DAP/Py-T) supramol. complexes. Transmission electron microscopy images revealed that this complex was an efficient dispersant of carbon nanotubes (CNTs). Indeed, it could disperse CNTs in both polar and nonpolar media, the direct result of combining two modes of secondary noncovalent bonding: multiple hydrogen bonding and π-π interactions. Furthermore, CNT composites fabricated with biocompatible polymers and high value of Tg should enable the development of bio-inspired carbon nanostructures and lead the way toward their biomedical applications. In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3Recommanded Product: 1075-62-3).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 1075-62-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Introduction of a new synthetic route about N-(6-Aminopyridin-2-yl)acetamide

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Safety of N-(6-Aminopyridin-2-yl)acetamide, blongs to pyridine-derivatives compound. Safety of N-(6-Aminopyridin-2-yl)acetamide

A. N-(2-Dimethylaminoethyl)-N-(6-amino-2-pyridyl)acetamide The title compound is obtained by following the procedure of part A of Example 13 but substituting an equivalent weight of N-(6-amino-2-pyridyl)acetamide for N-(5-methyl-2-pyridyl)acetamide. The product has b.p. 140-178/0.6 mm.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, and friends who are interested can also refer to it.

Reference:
Patent; Merck & Co., Inc.; US4203988; (1980); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Introduction of a new synthetic route about N-(6-Aminopyridin-2-yl)acetamide

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Safety of N-(6-Aminopyridin-2-yl)acetamide, blongs to pyridine-derivatives compound. Safety of N-(6-Aminopyridin-2-yl)acetamide

A. N-(2-Dimethylaminoethyl)-N-(6-amino-2-pyridyl)acetamide The title compound is obtained by following the procedure of part A of Example 13 but substituting an equivalent weight of N-(6-amino-2-pyridyl)acetamide for N-(5-methyl-2-pyridyl)acetamide. The product has b.p. 140-178/0.6 mm.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, and friends who are interested can also refer to it.

Reference:
Patent; Merck & Co., Inc.; US4203988; (1980); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Brief introduction of 1075-62-3

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, other downstream synthetic routes, hurry up and to see.

Synthetic Route of 1075-62-3 ,Some common heterocyclic compound, 1075-62-3, molecular formula is C7H9N3O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

In a 25 mL round bottom flask, 5-(methoxymethylene)-2,2-dimethyl-i,3-dioxane- 4,6-dione (6.06 g, 32.5 mmol) was added to a stirred mixture of N-(6-aminopyridin-2- yl)acetamide (4.10 g, 27.1 mmol) in EtOH (5 ml) at room temperature. After the reaction mixture was stirred at 80C for 3 hr, it was cooled down to room temperature and then concentrated under vacuum to give the title compound as a solid. LCMS (ESI) calc?d for C,4H,5N305 [M+i ]: 306,found: 306; ?H NMR (300 MHz, CDC13): oei i.18(s, 1H), 9.27 (d, J= 4.2 Hz, 1H), 8.06 (d, J= 8.4 Hz, 1H), 7.90 (s,1H),7.77-7.72(m,1H), 6.73 (d, J= 7.8 Hz, 1H),2.26 (s,3H), 1.76 (s,6H).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1075-62-3, N-(6-Aminopyridin-2-yl)acetamide, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; MERCK SHARP & DOHME CORP.; BENNETT, Frank; JIANG, Jinlong; PASTERNAK, Alexander; DONG, Shuzhi; GU, Xin; SCOTT, Jack D.; TANG, Haiqun; ZHAO, Zhiqiang; HUANG, Yuhua; HUNTER, David; YANG, Dexi; ZHANG, Zhibo; FU, Jianmin; BAI, Yunfeng; ZHENG, Zhixiang; ZHANG, Xu; YOUNG, Katherine; XIAO, Li; (580 pag.)WO2016/206101; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem