Category: 109660-12-0

On December 7, 2000, Davenport, Adam J.; Davies, David L.; Fawcett, John; Garratt, Shaun A.; Russell, David R. published an article.Quality Control of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine The title of the article was Arene ruthenium complexes with pyridyloxazolines: synthesis and applications as asymmetric catalysts for Diels-Alder reactions. And the article contained the following:

Reaction of the dimers [RuCl2(arene)]2 (arene = mesitylene, p-cymene, benzene, C6Me6) with pyridyloxazolines (pymox) gave complexes [RuCl(pymox)(arene)][SbF6] which have been fully characterized. Using chiral ligands diastereomers are formed, the diastereoselectivity depending on the substituents on the arene and on the oxazoline. The complexes [RuCl(Me2-pymox)(mes)][SbF6], [RuCl(Ph-pymox)(mes)][SbF6], [RuCl(iPr-pymox)(mes)][SbF6] and [RuCl(indanyl-pymox)(mes)][SbF6] (mes = mesitylene) have been characterized by x-ray crystallog. Treatment of these cations with AgSbF6 generates dications which in some cases can be isolated as aqua species [Ru(OH2)(pymox)(arene)]2+; these dications are enantioselective catalysts for Diels-Alder reactions of acroleins and dienes; a mechanism is proposed which accounts for the observed enantioselectivity. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Quality Control of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

The Article related to arene ruthenium pyridyloxazoline preparation asym catalyst diels alder, crystal mol structure arene ruthenium pyridyloxazoline complex, Organometallic and Organometalloidal Compounds: Group Viii – Co, Ni, Ru, Rh, Pd, Os, Ir, Pt and other aspects.Quality Control of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On April 2, 2009, Yi, Chae S.; Kwon, Ki-Hyeok; Lee, Do W. published an article.Category: pyridine-derivatives The title of the article was Aqueous Phase C-H Bond Oxidation Reaction of Arylalkanes Catalyzed by a Water-Soluble Cationic Ru(III) Complex [(pymox-Me2)2RuCl2]+BF4-. And the article contained the following:

The cationic complex [(pymox-Me2)RuCl2]+BF4- was found to be a highly effective catalyst for the C-H bond oxidation reaction of arylalkanes in water. For example, the treatment of ethylbenzene (1.0 mmol) with t-BuOOH (3.0 mmol) and 1.0 mol % of the Ru catalyst in water (3 mL) cleanly produced PhCOCH3 at room temperature Both a large kinetic isotope effect (kH/kD = 14) and a relatively large Hammett value (ρ = -1.1) suggest a solvent-caged oxygen rebounding mechanism via a Ru(IV)-oxo intermediate species. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Category: pyridine-derivatives

The Article related to aqueous carbon hydrogen bond oxidation arylalkane cationic ruthenium complex, Physical Organic Chemistry: Oxidation-Reduction, Including Dehydrogenation and Hydrogenolysis and other aspects.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 10, 2020, Li, Hanyuan; Ma, Biao; Liu, Qi-Sheng; Wang, Mei-Ling; Wang, Zhen-Yu; Xu, Hui; Li, Ling-Jun; Wang, Xing; Dai, Hui-Xiong published an article.COA of Formula: C10H12N2O The title of the article was Transformations of Aryl Ketones via Ligand-Promoted C-C Bond Activation. And the article contained the following:

The coupling of aromatic electrophiles (aryl halides, aryl ethers, aryl acids, aryl nitriles etc.) with nucleophiles is a core methodol. for the synthesis of aryl compounds Transformations of aryl ketones in an analogous manner via carbon-carbon bond activation could greatly expand the toolbox for the synthesis of aryl compounds due to the abundance of aryl ketones. An exploratory study of this approach is typically based on carbon-carbon cleavage triggered by ring-strain release and chelation assistance, and the products are also limited to a specific structural motif. Here we report a ligand-promoted β-carbon elimination strategy to activate the carbon-carbon bonds, which results in a range of transformations of aryl ketones, leading to useful aryl borates, and also to biaryls, aryl nitriles, and aryl alkenes. The use of a pyridine-oxazoline ligand is crucial for this catalytic transformation. A gram-scale borylation reaction of an aryl ketone via a simple one-pot operation is reported. The potential utility of this strategy is also demonstrated by the late-stage diversification of drug mols. probenecid, adapalene, and desoxyestrone, the fragrance tonalid as well as the natural product apocynin. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).COA of Formula: C10H12N2O

The Article related to aryl borate preparation ketoarene ligand promoted bond activation, c−c bond activation, pd catalysis, aryl ketones, borylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.COA of Formula: C10H12N2O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On May 7, 2021, Milic, Mira; Targos, Karina; Tellez Chavez, Magda; Thompson, Madison A. M.; Jennings, Julia J.; Franz, Annaliese K. published an article.Reference of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine The title of the article was NMR Quantification of Hydrogen-Bond-Accepting Ability for Organic Molecules. And the article contained the following:

The hydrogen-bond-accepting abilities for more than 100 organic mols. are quantified using 19F and 31P NMR spectroscopy with pentafluorobenzoic acid (PFBA) and phenylphosphinic acid (PPA) as com. available, inexpensive probes. Anal. of pyridines and anilines with a variety of electronic modifications demonstrates that changes in NMR shifts can predict the secondary effects that contribute to H-bond-accepting ability, establishing the ability of PFBA and PPA binding to predict electronic trends. The H-bond-accepting abilities of various metal-chelating ligands and organocatalysts are also quantified. The measured Δδ(31P) and Δδp(19F) values correlate strongly with Hammett parameters, pKa of the protonated HBA, and proton-transfer basicity (pKBH+). The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Reference of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

The Article related to hydrogen bond accepting ability nmr chem shift, Physical Organic Chemistry: Resonance Spectra (Electron Spin, Nuclear Magnetic and Fourier Transform Nuclear Magnetic, Quadrupole, etc.) and other aspects.Reference of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Zi-Qi; Fu, Yue; Deng, Ruohan; Tran, Van T.; Gao, Yang; Liu, Peng; Engle, Keary M. published an article in 2020, the title of the article was Ligand-controlled regiodivergence in nickel-catalyzed hydroarylation and hydroalkenylation of alkenyl carboxylic acids.Safety of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine And the article contains the following content:

A nickel-catalyzed regiodivergent hydroarylation and hydroalkenylation of unactivated alkenyl carboxylic acids is reported, whereby the ligand environment around the metal center dictates the regiochem. outcome. Markovnikov hydrofunctionalization products are obtained under mild ligand-free conditions, with up to 99% yield and >20:1 selectivity. Alternatively, anti-Markovnikov products can be accessed with a novel 4,4-disubstituted Pyrox ligand I in excellent yield and >20:1 selectivity. Both electronic and steric effects on the ligand contribute to the high yield and selectivity. Mechanistic studies suggest a change in the turnover-limiting and selectivity-determining step induced by the optimal ligand. DFT calculations reveal that in the anti-Markovnikov pathway, repulsion between the ligand and the alkyl group is minimized (by virtue of it being 1° vs. 2°) in the rate- and regioselectivity-determining transmetalation transition state. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Safety of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

The Article related to hydroarylation regiodivergent alkenyl carboxylic acid boronic acid nickel catalyst, hydroalkenylation regiodivergent alkenyl carboxylic acid boronic acid nickel catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Safety of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ghorai, Debasish; Mueller, Valentin; Keil, Helena; Stalke, Dietmar; Zanoni, Giuseppe; Tkachenko, Boryslav A.; Schreiner, Peter R.; Ackermann, Lutz published an article in 2017, the title of the article was Secondary Phosphine Oxide Preligands for Palladium-Catalyzed C-H (Hetero)Arylations: Efficient Access to Pybox Ligands.Related Products of 109660-12-0 And the article contains the following content:

C-H arylations of oxazolines were accomplished with a well-defined palladium catalyst derived from a secondary bisdiamantyl phosphine oxide. The single-component secondary phosphine oxide (SPO)-palladium complex enabled C-H activations with aryl bromides and challenging aryl chlorides in the absence of directing groups, setting the stage for the step-economical synthesis of pybox ligands under racemization-free reaction conditions. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Related Products of 109660-12-0

The Article related to bisdiamantyl phosphine oxide palladium complex catalyst preparation crystal structure, oxazoline aryl halide phosphine oxide palladium complex catalyst arylation, aryloxazoline regioselective preparation and other aspects.Related Products of 109660-12-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On July 30, 1999, Franco, D.; Panyella, D.; Rocamora, M.; Gomez, M.; Clinet, J. C.; Muller, G.; Dunach, E. published an article.Recommanded Product: 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine The title of the article was Electrochemical cleavage of allyl aryl ethers and allylation of carbonyl compounds: umpolung of allyl-palladium species. And the article contained the following:

The electrochem., Pd-catalyzed cleavage of the carbon-oxygen bond of allyl aryl ethers has been examined; the method constitutes a new alternative for allyl ether deprotection. The allyl transfer from the allyl ether to the carbonyl group in 2-allyloxy benzaldehyde is reported and is an example of allyl-Pd reactivity umpolung. Pd(II) complexes, associated to several nitrogen ligands are efficient catalyst precursors for these electrochem. reactions. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Recommanded Product: 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

The Article related to allyl aryl ether electrochem cleavage, electrochem ether cleavage catalyst palladium complex, aryl allyl ether deprotection electrochem cleavage, allylsalicylaldehyde allyl transfer palladium chloride catalyst and other aspects.Recommanded Product: 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On July 13, 1999, Cheng, Jianjun; Deming, Timothy J. published an article.COA of Formula: C10H12N2O The title of the article was Screening of Optically Active Nickel Initiators for Enantioasymmetric Polymerization of γ-Benzyl Glutamate-N-Carboxyanhydride. And the article contained the following:

The use of chiral pyridinyl oxazoline ligands in nickel initiators to enantioasym. polymerize γ-benzyl glutamate N-carboxyanhydride (I) was studied. Catalysts prepared from 4,4-dimethyl-(2-pyridinyl)-2-oxazoline and Ni(COD) displayed I polymerization activity which was virtually identical to that of bipyridine-Ni(COD). The kinetic selectivity for the D-antipode displayed by catalyst prepared from (4S)-4-tert-butyl-(2-pyridinyl)-2-oxazoline in homopolymerization was also displayed in polymerization of the racemate. The selectivity of the catalysts was highly sensitive to substitution on the 4 position of the oxazoline ring. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).COA of Formula: C10H12N2O

The Article related to oxazoline nickel catalyst polymerization benzyl glutamate, enantioasym polymerization benzyl glutamate nickel catalyst, polybenzyl glutamate preparation catalyst nickel, pyridine nickel catalyst polymerization benzyl glutamate and other aspects.COA of Formula: C10H12N2O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 31, 1987, Dondoni, Alessandro; Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola published an article.Synthetic Route of 109660-12-0 The title of the article was Palladium-catalyzed coupling of oxazol-2-yl- and 2-oxazolin-2-yltrimethylstannanes with aromatic halides. A new entry to 2-aryl and 2-heteroaryl oxazoles and oxazolines. And the article contained the following:

Coupling of lithiated 4-methyloxazole and 4,4-dimethyl-2-oxazoline with RX (R = Ph, p-FC6H4, p-tolyl, p-MeSC6H4, o-CNC6H4, thienyl, pyridyl, 2-thiazolyl, 3-furyl, naphthyl, quinolyl, X = Cl, Br, iodo) in benzene in the presence of (Ph3P)4P gave 70-100% 4 oxazoles I and 16 oxazolines II. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Synthetic Route of 109660-12-0

The Article related to safety toxic chlorotrimethylstannane, oxazole aryl, oxazoline aryl, coupling oxazolylstannane aryl halide, arylation oxazoline oxazole, stannane oxazolyl coupling aryl halide, palladium catalyst coupling oxazolylstannanehaloarene and other aspects.Synthetic Route of 109660-12-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On March 14, 2005, Munoz, M. Paz; Adrio, Javier; Carretero, Juan Carlos; Echavarren, Antonio M. published an article.Recommanded Product: 109660-12-0 The title of the article was Ligand Effects in Gold- and Platinum-Catalyzed Cyclization of Enynes: Chiral Gold Complexes for Enantioselective Alkoxycyclization. And the article contained the following:

Phosphine and bidentate N-N ligands inhibit the Alder-ene-type cycloisomerization of enynes catalyzed by Pt(II) and favor the alkoxycyclization process. The enantioselective Pt(II)-catalyzed alkoxycyclization has been studied in the presence of chiral mono- and bidentate phosphines, as well as chiral bidentate N-N ligands. Modest levels of enantioselection (up to 50% ee) have been obtained with Tol-BINAP as ligand. The alkoxycyclizations with a catalyst formed from [Au(L)Cl]/AgX proceed more readily, and up to 94% ee’s have been obtained using [(AuCl)2(Tol-BINAP)] (1) as the precatalyst. X-ray crystal structures of Au(I) complexes 1 and chloro-(R)-2-(tert-butylsulfenyl)-1-(diphenylphosphino)ferrocene gold(I) show the AuCl fragments monocoordinated with the P centers of the chiral phosphine ligands. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Recommanded Product: 109660-12-0

The Article related to enyne phosphine platinum gold complex catalyzed stereoselective alkoxycyclization alc, platinum chiral phosphine complex preparation methoxycyclization catalyst, gold chiral phosphine complex preparation alkoxycyclization catalyst and other aspects.Recommanded Product: 109660-12-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem