Related Products of 1097839-70-7, Adding some certain compound to certain chemical reactions, such as: 1097839-70-7, name is 5-Methoxy-2-methyl-1H-pyrrolo[2,3-c]pyridine,molecular formula is C9H10N2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1097839-70-7.
A solution of 5-methoxy-2-methyl-lH-pyrtauolo[2,3-c]pyridine (530mg, 3.3mmol), Cs2CO3 (3eq) and methyl (2R)-2-[3-(bromomethyl)-4-chlorophenoxy]propanoate (1.2eq) in DMF (2OmL) was stirred at 25 C for 8 hours. The reaction mixture was diluted with EtOAc, washed with water (2x) and satd NH4Cl (Ix). The organic layer was dried over Na2SO4 and concentrated. Purification via flash chromatography eluding with a gradient of 0 to 100% EtOAc/hexanes provided methyl (2R)-2-{4-chloro-3-[(5-methoxy-2-methyl-lH-pyrrolo[2,3- c]pyridin-l-yl)methyl]phenoxy}propanoate as a yellow syrup.1H NMR (500 MHz, CDCl3): delta 8.02 (s, IH), 7.25 (d, IH), 6.82 (s, IH), 6.68 (dd, IH), 6.25 (s, IH), 5.76 (d, IH), 5.26 (s, 2H), 4.36 (q, IH), 3.91 (s, 3H), 3.54 (s, 3H), 2.31 (s, 3H), 1.42 (d, 3H).
According to the analysis of related databases, 1097839-70-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERCK & CO., INC.; WO2009/5672; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem