Category: 1122-54-9

Luo, Mu-Jia; Ouyang, Xuan-Hui; Zhu, Yan-Ping; Li, Yang; Li, Jin-Heng published their research in Green Chemistry in 2021. The article was titled 《Metal-free electrochemical [3 + 2] heteroannulation of anilines with pyridines enabled by dual C-H radical aminations》.Related Products of 1122-54-9 The article contains the following contents:

An unprecedented metal-/external-oxidant-free electrochem. intermol. [3+2] heteroannulation of anilines with electron-deficient pyridines enabled by dual C-H radical aminations for producing functionally diverse benzo[4,5]imidazo[1,2-a]pyridines was described. The site-selectivity of aminations of aryl C(sp2)-H bonds relied on the electronic effect of two reaction partners: each contributed two reactive sites (a C(sp2)-H bond and a nitrogen atom-based functional group) and the electron-withdrawing groups at the 4 position of the pyridine ring were crucial. Mechanistic studies have shown that this method sequence consisted of the generation of the nitrogen-centered radical (NCR) and the pyridine radical anion, radical coupling, and dual C-N aminations. In the experiment, the researchers used 4-Acetylpyridine(cas: 1122-54-9Related Products of 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Related Products of 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Understanding the Role of Surface Heterogeneities in Electrosynthesis Reactions》 was written by Carvalho, O. Quinn; Adiga, Prajwal; Murthy, Sri Krishna; Fulton, John L.; Gutierrez, Oliver Y.; Stoerzinger, Kelsey A.. Formula: C7H7NO And the article was included in iScience in 2020. The article conveys some information:

In this perspective, we highlight the role of surface heterogeneity in electrosynthesis reactions. Heterogeneities may come in the form of distinct crystallog. facets, boundaries between facets or grains, or point defects. We approach this topic from a foundation of surface science, where signatures from model systems provide understanding of observations on more complex and higher-surface-area materials. In parallel, probe-based techniques can inform directly on spatial variation across electrode surfaces. We call attention to the role spectroscopy can play in understanding the impact of these heterogeneities in electrocatalyst activity and selectivity, particularly where these surface features have effects extending into the electrolyte double layer. The experimental process involved the reaction of 4-Acetylpyridine(cas: 1122-54-9Formula: C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Formula: C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Synlett included an article by Schneekoenig, Jacob; Junge, Kathrin; Beller, Matthias. Recommanded Product: 4-Acetylpyridine. The article was titled 《Manganese Catalyzed Asymmetric Transfer Hydrogenation of Ketones Using Chiral Oxamide Ligands》. The information in the text is summarized as follows:

The asym. transfer hydrogenation of ketones using iso-Pr alc. (IPA) as hydrogen donor in the presence of novel manganese catalysts is explored. The selective and active systems are easily generated in situ from [MnBr(CO)5] and inexpensive C2-sym. bisoxalamide ligands. Under the optimized reaction conditions, the Mn-derived catalyst gave higher enantioselectivity compared with the related ruthenium catalyst. In the experimental materials used by the author, we found 4-Acetylpyridine(cas: 1122-54-9Recommanded Product: 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Hua, Manli; Song, Jinliang; Huang, Xin; Fan, Honglei; Wu, Tianbin; Meng, Qinglei; Zhang, Zhanrong; Han, Buxing published an article in Chemical Science. The title of the article was 《Highly efficient C(CO)-C(alkyl) bond cleavage in ketones to access esters over ultrathin N-doped carbon nanosheets》.Name: 4-Acetylpyridine The author mentioned the following in the article:

A series of porous and ultrathin N-doped carbon nanosheets (denoted as CN-X, where X represents the pyrolysis temperature) as heterogeneous metal-free catalysts was reported. It was observed that the fabricated CN-800 could efficiently catalyze the oxidative cleavage of the C(CO)-C bond in various ketones RC(O)CH3 [R = Ph, naphthalen-1-yl, thiophen-2-yl, pyridin-4-yl, etc.] to generate the corresponding Me esters RC(O)OCH3 at 130°C without using any addnl. base. Detailed investigations revealed that the higher content and electron d. of the graphitic-N species contributed to the excellent performance of CN-800. The high surface area affording active sites that are more easily accessed, could also enhance the catalytic activity. The catalysts have great potential for practical applications because of some obvious advantages, such as low cost, neutral reaction conditions, heterogeneous nature, high efficiency, and broad ketone scope. This is the first work on efficient synthesis of Me esters via oxidative esterification of ketones over heterogeneous metal-free catalysts. After reading the article, we found that the author used 4-Acetylpyridine(cas: 1122-54-9Name: 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Name: 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Green Chemistry included an article by Chen, Jinjin; Meng, Huanxin; Zhang, Feng; Xiao, Fuhong; Deng, Guo-Jun. Synthetic Route of C7H7NO. The article was titled 《Transition-metal-free selective pyrimidines and pyridines formation from aromatic ketones, aldehydes and ammonium salts》. The information in the text is summarized as follows:

An efficient synthesis of pyrimidines and pyridines was developed from readily available aromatic ketones, aldehydes and ammonium salts under transition-metal-free conditions. In this strategy, ammonium salts were used as nitrogen sources and only water was generated as a nontoxic byproduct. A catalytic amount of NaIO4 played an important role in the selectivity control, whereas substituted pyridines were dominantly formed in its absence. The experimental process involved the reaction of 4-Acetylpyridine(cas: 1122-54-9Synthetic Route of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Synthetic Route of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《A simple and efficient asymmetric hydrogenation of heteroaromatic ketones with iridium catalyst composed of chiral diamines and achiral phosphinesã€?was written by Li, Chun; Lu, Xunhua; Wang, Mengna; Zhang, Ling; Jiang, Jian; Yan, Shunfa; Yang, Yuanyong; Zhao, Yonglong; Zhang, Lin. HPLC of Formula: 1122-54-9 And the article was included in Tetrahedron Letters in 2020. The article conveys some information:

An efficient iridium catalyst composed of a simple and com. available o-methoxytriphenylphosphine and 9-Amino (9-deoxy) epi-cinchonine was applied to the asym. hydrogenation of heteroaromatic ketones. A range of simple heteroaromatic ketones were hydrogenated with good to excellent enantioselectivities and high activities. In particular, thiophene ketones and furyl ketones furnished 98.6% ee with up to 2.18 x 104(1/h) TOF. This catalytic system was of practical value. In the experiment, the researchers used many compounds, for example, 4-Acetylpyridine(cas: 1122-54-9HPLC of Formula: 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. HPLC of Formula: 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

HPLC of Formula: 1122-54-9In 2020 ,《A convenient method for synthesis of terpyridines via a cooperative vinylogous anomeric based oxidationã€?was published in RSC Advances. The article was written by Karimi, Fatemeh; Yarie, Meysam; Zolfigol, Mohammad Ali. The article contains the following contents:

The presented study is the first report of the synthesis of terpyridines I (R = pyridin-4-yl, pyridin-3-yl, pyridin-2-yl; R1 = Ph, thiophen-2-yl, pyridin-4-yl, etc.) in the presence of a nanomagnetic catalyst instead of harmful reagents. Herein, Fe3O4@O2PO2(CH2)2NH3+CF3CO2- as a retrievable nanocatalyst with magnetic properties was applied for the multi-component reaction between acetylpyridine derivatives RC(O)Me (2 or 3 or 4-isomer), aryl aldehydes R1CHO and ammonium acetate under conventional heating conditions in the absence of any solvent. The derived terpyridines I were obtained with acceptable yields and brief reaction times via a cooperative vinylogous anomeric based oxidation route. Fe3O4@O2PO2(CH2)2NH3+CF3CO2- showed a high capability for recovery and reuse in the mentioned reaction. In the experimental materials used by the author, we found 4-Acetylpyridine(cas: 1122-54-9HPLC of Formula: 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. HPLC of Formula: 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Weber, Stefan; Bruenig, Julian; Veiros, Luis F.; Kirchner, Karl published their research in Organometallics in 2021. The article was titled 《Manganese-Catalyzed Hydrogenation of Ketones under Mild and Base-free Conditionsã€?Category: pyridine-derivatives The article contains the following contents:

In this paper, several Mn(I) complexes were applied as catalysts for the homogeneous hydrogenation of ketones. The most active precatalyst is the bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dippe)(CO)3(CH2CH2CH3)]. The reaction proceeds at room temperature under base-free conditions with a catalyst loading of 3 mol % and a hydrogen pressure of 10 bar. A temperature-dependent selectivity for the reduction of α,β-unsaturated carbonyls was observed At room temperature, the carbonyl group was selectively hydrogenated, while the C:C bond stayed intact. At 60°, fully saturated systems were obtained. A plausible mechanism based on DFT calculations which involves an inner-sphere hydride transfer is proposed. In the experiment, the researchers used many compounds, for example, 4-Acetylpyridine(cas: 1122-54-9Category: pyridine-derivatives)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Related Products of 1122-54-9In 2022 ,《Tailoring the molecular structure of pyridine-based polymers for enhancing performance of anion exchange electrolyte membranesã€?appeared in Renewable Energy. The author of the article were Xu, Shicheng; Wu, Wanlong; Wan, Ruiying; Wei, Wei; Li, Yujiao; Wang, Jin; Sun, Xiaoqi; He, Ronghuan. The article conveys some information:

Anion exchange membranes (AEMs) with high ionic conductivity and excellent chem. stability are desired for relevant electrochem. devices. We designed and prepared pyridine based ether free poly (biphenyl pyridine) (PBP) membranes by modifying pyridinium with both hydrophilic and hydrophobic end groups via the Menshutkin reaction. The grafted Et tri-Me ammonium and hexyl pendants assisted the formation of well-connected ion transport channels in the membranes according to the results of transmission electron microscopy (TEM). The highest conductivity of 117 mS cm-1 to hydroxide ions and 73 mS cm-1 to bromide ions was achieved, resp., at 90 °C by the prepared membranes. The conductivity retention rate of the AEMs was within 84-93% after soaking in 1 mol L-1 KOH at 80 °C for 1008 h. The membrane-based single fuel cell exhibited an open circuit voltage of 0.99 V and a peak power d. of 241 mW cm-2 at 80 °C by fueling with humidified H2 and O2 without backpressure. The aqueous zinc bromine battery with a composite separator of the polymer impregnated glass fiber achieved 92.6% of the coulombic efficiency. The assembled battery retained 98% of initial capacity after 157 cycles at a c.d. of 6 mA cm-2. In the experiment, the researchers used many compounds, for example, 4-Acetylpyridine(cas: 1122-54-9Related Products of 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Related Products of 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chung, Hyunho; Kim, Jeongyun; Gonzalez-Montiel, Gisela A.; Ha-Yeon Cheong, Paul; Lee, Hong Geun published an article in 2021. The article was titled 《Modular Counter-Fischer-Indole Synthesis through Radical-Enolate Couplingã€? and you may find the article in Organic Letters.Application In Synthesis of 4-Acetylpyridine The information in the text is summarized as follows:

A single-electron transfer mediated modular formation of indoles e.g., 2-phenyl-1H-indole from a 2-iodoaniline derivatives 2-I-3-R-4-R1-5-R2-6-R3C6NH(R4) [R = H, Cl, Br; R1 = H, Me, CN, Br, (tert-butoxy)carbonyl, etc.; R2 = H, Me, OMe, Cl, Br; R3 = H, Cl, Br; R4 = H, Me, Bn, 1-hexyl, cyclohexyl; R2R3 = -CH=CHCH=CH-] and a ketones e.g., acetophenone has been developed. This transition-metal-free reaction shows a broad substrate scope and unconventional regioselectivity trends. Moreover, important functional groups for further transformation are tolerated under the reaction conditions. D. functional theory studies reveal that the reaction proceeds by metal coordination, which converts a disfavored 5-endo-trig cyclization to an accessible 7-endo-trig process. In the experiment, the researchers used many compounds, for example, 4-Acetylpyridine(cas: 1122-54-9Application In Synthesis of 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Application In Synthesis of 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem