Category: 1122-54-9

Application of 1122-54-9In 2019 ,《The positional isomeric effects induced various phosphorescence: Switchable properties through acid-base vapor stimulation》 appeared in Journal of Molecular Structure. The author of the article were Li, Bin; Yong, Guoping. The article conveys some information:

Three novel positional isomers, namely (E)-3-(2-chloroimidazo[1,2-a]pyridin-3-yl)-1-(pyridin-2-yl)prop-2-en-1-one , (E)-3-(2-chloroimidazo[1,2-a]pyridin-3-yl)-1-(pyridin-3-yl)prop-2-en-1-one and (E)-3-(2-chloroimidazo[1,2-a]pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one, were obtained through a mild approach. Powder x-ray diffraction patterns demonstrate their various stacking structures, attributed to positional isomeric effects. Furthermore, these positional isomers exhibit different phosphorescent colors and quantum yields. These positional isomers also reveal reversible phosphorescent color switching in the response to acid-base vapor stimuli. The present work provides a promising approach for synthesizing organic materials and a new access to develop dynamic functional materials which can be reversibly switched between different phosphorescence based on external acid-base vapor stimuli. In the part of experimental materials, we found many familiar compounds, such as 4-Acetylpyridine(cas: 1122-54-9Application of 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Application of 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wu, Ye-bin; Wu, You-zhi; Wu, Jian; Xu, Dan; Jiang, Hui; Chang, Wen-wu; Ma, Chang-you published their research in Journal of Organic Chemistry in 2021. The article was titled 《Copper-Catalyzed Regioselective Coupling of Tosylhydrazones and 2-Pyridones: A Strategy for the Production of N-Alkylated Compounds》.Synthetic Route of C7H7NO The article contains the following contents:

The highly regioselective N-alkylation reaction of 2-pyridones was achieved through hydrazone chem., especially for substrates with bulky secondary alkyl groups. Herein, a copper-catalyzed regioselective coupling of tosylhydrazones and 2-pyridones/isoquinolinones for the synthesis of N-alkylated compound such as N-alkylated pyridones I [R = CH(Me)(4-MeOC6H4), R1 = H, CN, C(O)OMe; R2 = H, OMe; R3 = H, F, Br] isoquinolinones II [R1 = H, Me; R2 = Ph, 3-O2NC6H4, 2-ClC6H4, etc.] was described. The experimental process involved the reaction of 4-Acetylpyridine(cas: 1122-54-9Synthetic Route of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Synthetic Route of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Well-defined, linear, wholly aromatic polymers with controlled content and position of pyridine moieties in macromolecules from one-pot, room temperature, metal-free step-polymerizations》 was published in Polymer Chemistry in 2020. These research results belong to Cetina-Mancilla, Enoc; Olvera, Lilian I.; Balmaseda, Jorge; Forster, Michael; Ruiz-Trevino, F. Alberto; Cardenas, Jorge; Vivaldo-Lima, Eduardo; Zolotukhin, Mikhail G.. Name: 4-Acetylpyridine The article mentions the following:

Synthesis of processable, aromatic pyridine-containing polymers has always been a great challenge. Here, we report for the first time a robust, low-cost synthesis of well defined, high mol. weight, linear, wholly aromatic polymers with rigid ether-bond-free aryl backbones, where the proportion and position of pyridine moieties and spacer lengths between them in the macromols. are fully controlled. The polymers, in nearly quant. yields, were obtained by one-pot, room temperature, metal-free, non-stoichiometric superacid catalyzed step-polymerization of 4-acetylpyridine (and its mixtures with 2,2,2-trifluoroacetophenone) with multiring aromatic hydrocarbons: biphenyl, meta- and para-terphenyl, and para-quaterphenyl, in the mixture of trifluoromethanesulfonic acid with methylene chloride and trifluoroacetic acid. The polymers are highly soluble in most common solvents and form flexible and tough films with tensile strength in the range of 72-92 MPa. 1H and 13C NMR analyses of the synthesized polymers revealed high regio-selectivity of the polymer forming reaction affording linear structures with para-substitution in the phenylene fragments of the main chains. The mol. weights of the polymers ranged from 20 000 to 100 000 g mol-1, whereas the polydispersity is generally well below 2. The polymers exhibited also high thermostability with Tg > 400°, weight loss temperatures (N2, onset) ca. 485°, char yields of 70-75 at 800° and high chem. stability. Room temperature reactions of the polymers with methyl(trifluoromethylsulfonate) afford the N-methylated cationic polymers. Certain studies on the phys. properties and gas separation of the polymers are highlighted. The experimental part of the paper was very detailed, including the reaction process of 4-Acetylpyridine(cas: 1122-54-9Name: 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Name: 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

COA of Formula: C7H7NOIn 2019 ,《Transition-metal-free catalyzed [3+2] cycloadditions/oxidative aromatization reactions for the synthesis of annulated indolizines》 appeared in New Journal of Chemistry. The author of the article were Zhang, Qianwei; Wang, Bin; Ma, Huifang; Ablajan, Keyume. The article conveys some information:

In this study, transition-metal-free catalyzed [3+2] cycloadditions/oxidative aromatization three-component reactions for the successful direct construction of pyrrolo[3,4-a]indolizine-1,3(2H)-diones via pyridinium ylides are reported. This method utilizes readily available pyridines, acetophenones and maleimides as starting materials in the presence of TBAI (N-tetrabutylammonium iodide)/TBHP (tert-Bu hydroperoxide), with a wide substrate scope and moderate to good yields, avoiding the use of metal catalysts and generation of halides. The experimental part of the paper was very detailed, including the reaction process of 4-Acetylpyridine(cas: 1122-54-9COA of Formula: C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.COA of Formula: C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kumar, Ravi; Rawal, Parveen; Banerjee, Indrani; Pada Nayek, Hari; Gupta, Puneet; Panda, Tarun K. published an article in 2022. The article was titled 《Catalytic Hydroboration and Reductive Amination of Carbonyl Compounds by HBpin using a Zinc Promoter》, and you may find the article in Chemistry – An Asian Journal.Computed Properties of C7H7NO The information in the text is summarized as follows:

The chemoselective hydroboration of aldehydes and ketones, catalyzed by Zinc(II) complexes [κ2-(PyCH:NR)ZnX2] (1, R = CPh3, X = Cl; 2, R = 2,6-iPr2C6H3, X = I), by pinacolborane (HBpin) at ambient temperature and under solvent-free conditions, which produced the corresponding borate esters in high yield, is reported. Zinc metal complexes 1 and 2 were derived in 80-90% yield from the reaction of iminopyridine [PyCH:NR] with anhydrous zinc dichloride in dichloromethane at room temperature The solid-state structures of both zinc complexes were confirmed using X-ray crystallog. Zinc complex 1 was also used as a competent pre-catalyst in the reductive amination of carbonyl compounds with HBpin under mild and solvent-free conditions to afford a high yield (up to 97%) of the corresponding secondary amines. The wider substrate scope of both reactions was explored. Catalytic protocols using zinc as a pre-catalyst demonstrated an atom-economic and green method with diverse substrates bearing excellent functional group tolerance. Computational studies established a plausible mechanism for catalytic hydroboration. In the experiment, the researchers used many compounds, for example, 4-Acetylpyridine(cas: 1122-54-9Computed Properties of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Computed Properties of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Safety of 4-AcetylpyridineIn 2022 ,《Thioamide synthesis via copper-catalyzed C-H activation of 1,2,3-thiadiazoles enabled by slow release and capture of thioketenes》 was published in Organic Chemistry Frontiers. The article was written by Lu, Changhui; Li, Xiaohong; Chang, Shunqin; Zhang, Yuqi; Xing, Donghui; Wang, Shuo; Lin, Yueping; Jiang, Huanfeng; Huang, Liangbin. The article contains the following contents:

A Cu-catalyzed thioacylation of amines via a C-H activation/coordinated stabilization protocol to ensure the slow-release of thioketenes, which are captured by various amines to afford thioamides was developed. This method was characterized by its simplicity, efficiency and broad substrate scope in both 1,2,3-thiadiazoles and amines. Its versatility was further illustrated by the late-stage thioamidation of N-containing drugs, peptides, catalysts, and ligands. Mechanism studies demonstrate that the active Cu(I) species was formed via the reduction of Cu(II) during the induction period, and the rate-determining step was the C-H activation of 1,2,3-thiadiazole. In the part of experimental materials, we found many familiar compounds, such as 4-Acetylpyridine(cas: 1122-54-9Safety of 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Safety of 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthetic Route of C7H7NOIn 2020 ,《Synthesis, antioxidant and antimicrobial properties of novel pyridyl-carbonyl thiazoles as dendrodoine analogs》 appeared in Turkish Journal of Chemistry. The author of the article were Sahin, Zafer; Biltekin, Sevde Nur; Yurttas, Leyla; Demirayak, Seref. The article conveys some information:

Marine compound dendrodoine was first obtained from tunicate species (Dendrodo grossularia), it has a five-membered ring, namely, it is a heterocycle thiadiazole, which is found rarely in natural sources. Following its biol. activities, novel analogs have been investigated recently. Synthesis of the analogs I (R1 = 2-pyridyl, 3-pyridyl, 4-pyridyl; R2 = pyrrolidin-1-yl, piperidin-1-yl, azepan-1-yl, etc.) for this study is realized with uncommon thiazole closure, including methylene-carbonyl condensation. As an alkaloid derivative, antioxidant properties were evaluated with DPPH and FRAP assays and antimicrobial effect with microdilution method. Among the series, few compds showed higher antioxidant activity than those having 3 or 4-pyridyl substituents. There is lesser activity for 2-pyridyl activity for 2-pyridyl containing group, which may be a result of intramol. interactions. No activity was observed against gram-neg. bacteria at 250μg/mL. Compound I (R1 = 2-pyridyl, 4-pyridyl; R2 = hexamethylamine) showed activity at 64μg/mL against S. aureus and I (R1 = 2-pyridyl; R2 = hexamethylamine) showed activity at 16μg/mL against S. epidermidis gram-pos. bacteria. Chloramphenicol showed activity against all microorganisms at 8-16μg/mL. Sixteen original dendrodoine analogs have been defined by close/higher activity compared to dendrodoine analogs and Trolox. The experimental process involved the reaction of 4-Acetylpyridine(cas: 1122-54-9Synthetic Route of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Synthetic Route of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application In Synthesis of 4-AcetylpyridineIn 2021 ,《Palladium(II)-catalyzed three-component tandem reactions: synthesis of multiply substituted quinolines》 appeared in Organic Chemistry Frontiers. The author of the article were Zhang, Yetong; Chen, Lepeng; Shao, Yinlin; Zhang, Fangjun; Chen, Zhongyan; Lv, Ningning; Chen, Jiuxi; Li, Renhao. The article conveys some information:

The three-component tandem reaction of 2-aminobenzonitriles, arylboronic acids and ketones allowing the synthesis of polysubstituted quinolines I [R1 = H, 7-Me, 6-F, etc.; R2 = Me, Ph, 2-thienyl, etc.; R3 = Ph, 2-naphthyl, 3-thienyl, etc.; R4 = H, Et, Br, etc.; R2R4 = CH2CH2CH2; CH2(CH2)2CH2, etc.] was reported. This strategy presented a practical, efficient, one-pot procedure that delivered functional quinolines in moderate to good yields with high functional group tolerance. To enrich the synthetic applications in accessing diverse quinolines, a new method for the introduction of halogen substituents into target products was developed as well, which showed potential for further synthetic elaborations.4-Acetylpyridine(cas: 1122-54-9Application In Synthesis of 4-Acetylpyridine) was used in this study.

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Application In Synthesis of 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Synthesis of 2-Arylpyridines and 2-Arylbipyridines via Photoredox-Induced Meerwein Arylation with in Situ Diazotization of Anilines》 was published in Journal of Organic Chemistry in 2020. These research results belong to Hagui, Wided; Soule, Jean-Francois. Computed Properties of C7H7NO The article mentions the following:

Herein a sustainable method for the preparation of 2-arylpyridines through C-H arylation of pyridines using in situ formed diazonium salts (from com. available aromatic amines) in the presence of a photoredox catalyst under blue light-emitting diode (LED) irradiation The reaction is tolerant to a wide range of functional groups (e.g., halogen, nitrile, formyl, acetyl, ester). Applications to the C-H bond arylation of bipyridine ligands is also presented. The experimental part of the paper was very detailed, including the reaction process of 4-Acetylpyridine(cas: 1122-54-9Computed Properties of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Computed Properties of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Synthesis and structure of lithium 3-trifluoromethyl-1,3-diketonates containing pyridyl substituents》 were Slepukhin, P. A.; Boltacheva, N. S.; Filyakova, V. I.; Charushin, V. N.. And the article was published in Russian Chemical Bulletin in 2019. HPLC of Formula: 1122-54-9 The author mentioned the following in the article:

Lithium 3-trifluoromethyl-1,3-diketonates containing pyridyl substituents were synthesized. The specific features of the crystal structures of Li (Z)-1,1,1-trifluoro-4-oxo-4-(pyridin-3-yl)- and (Z)-1,1,1-trifluoro-4-oxo-4-(pyridin-4-yl)but-2-en-2-olates were revealed by x-ray diffraction. These compounds have a polymeric structure with Li cations in different coordination modes. The 1,3-diketonate group is involved in chelation and formation of O bridges, thereby linking two types of Li atoms. The results came from multiple reactions, including the reaction of 4-Acetylpyridine(cas: 1122-54-9HPLC of Formula: 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.HPLC of Formula: 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem