Category: 1137-67-3

Synthetic Route of 1137-67-3, Adding some certain compound to certain chemical reactions, such as: 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole,molecular formula is C12H9N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1137-67-3.

Complex 1 waspreparedbylayeringmethod.Abufferlayerof asolution(10ml)ofacetonitrile-water(1:1,v/v)wascarefullylayeredover5mlofanaqueoussolutionof alpha-H3PMo12O40 6H2O(120mg,0.06mmol).Thenamethanol(5ml)of3-PyBim(23.4 mg,0.12mmol)wascarefullylayeredoverthebufferlayer.Tendayslater,redcrystalsappearedandwerecollectedanddriedin airafterquicklybeingwashedwithwater.Yield:108mg,91%based on alpha-H3PMo12O40 6H2O. Anal.Calcd(%)forC27H35Mo12-N7O44.5P: C,13.79;H,1.50;N,4.17;Found(%):C,13.71;H,1.42;N,4.08. IR(KBr) nu, cm1: fourcharacteristicvibrationsresultingfromheteropolyanionswiththeKegginstructure:803 nu(Mo-Oc), 878 nu(Mo-Ob), 961 nu(MoOt), 1065 nu(P-Oa); (Ot, terminal oxygenatomsconnecting oneMoatom;Ob, atomslocatedinasharedcornerbetweentwoMo 3O13 units; Oc, oxygenatomsconnectingedge-sharing MoO6 octahedra inaMo3O13 unit); andanothervibrationsresulting from3-PyBimmolecules:1449,1402,1316and1118

According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.

Reference:
Article; Wei, Mei-Lin; Wang, Yu-Xia; Wang, Xin-Jun; Journal of Solid State Chemistry; vol. 209; (2014); p. 29 – 36;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthetic Route of 1137-67-3, Adding some certain compound to certain chemical reactions, such as: 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole,molecular formula is C12H9N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1137-67-3.

Complex 1 waspreparedbylayeringmethod.Abufferlayerof asolution(10ml)ofacetonitrile-water(1:1,v/v)wascarefullylayeredover5mlofanaqueoussolutionof alpha-H3PMo12O40 6H2O(120mg,0.06mmol).Thenamethanol(5ml)of3-PyBim(23.4 mg,0.12mmol)wascarefullylayeredoverthebufferlayer.Tendayslater,redcrystalsappearedandwerecollectedanddriedin airafterquicklybeingwashedwithwater.Yield:108mg,91%based on alpha-H3PMo12O40 6H2O. Anal.Calcd(%)forC27H35Mo12-N7O44.5P: C,13.79;H,1.50;N,4.17;Found(%):C,13.71;H,1.42;N,4.08. IR(KBr) nu, cm1: fourcharacteristicvibrationsresultingfromheteropolyanionswiththeKegginstructure:803 nu(Mo-Oc), 878 nu(Mo-Ob), 961 nu(MoOt), 1065 nu(P-Oa); (Ot, terminal oxygenatomsconnecting oneMoatom;Ob, atomslocatedinasharedcornerbetweentwoMo 3O13 units; Oc, oxygenatomsconnectingedge-sharing MoO6 octahedra inaMo3O13 unit); andanothervibrationsresulting from3-PyBimmolecules:1449,1402,1316and1118

According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.

Reference:
Article; Wei, Mei-Lin; Wang, Yu-Xia; Wang, Xin-Jun; Journal of Solid State Chemistry; vol. 209; (2014); p. 29 – 36;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 1137-67-3 ,Some common heterocyclic compound, 1137-67-3, molecular formula is C12H9N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: 2-Substituted benzimidazole (0.01 M) was added to the ethanolic solution of benzamide (0.01M). Formaldehyde (37-41% w/v) (0.01 M) was added and the reaction mixture was then adjusted to the pH of 3.5 with concentrated HCl. The mixture was kept at efficient ice cooling for half an hour. Then, it was refluxed with stirring at 80 C for 10-12h. Formaldehyde (37-41% w/v) was added to the reaction mixture in portions for completion of the reaction. End of reaction was monitored by TLC. Reaction mixture was kept in refrigerator overnight. Solvent was evaporated under reduced pressure and product was collected, washed with water and recrystallized from ethanol.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1137-67-3, its application will become more common.

Reference:
Article; Sethi, Ritchu; Arora, Sandeep; Saini, Deepika; Singh, Thakur Gurjeet; Jain, Sandeep; Acta poloniae pharmaceutica; vol. 74; 5; (2017); p. 1413 – 1425;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole. This compound has unique chemical properties. The synthetic route is as follows. HPLC of Formula: C12H9N3

Step 2: 8-Fluoro-4-((2-(pyridin-3-yl)-1H-benzo[d]imidazol-1-yl)methyl)quinolin-2(1H)-one Sodium hydride (60% in mineral oil, 117 mg, 2.9 mmol) was added to 2-(pyridin-3-yl)-1H-benzo[d]imidazole (191 mg, 0.98 mmol) in DMF (5 mL) and stirred at RT for 15 min. 4-(Bromomethyl)-8-fluoroquinolin-2(1H)-one (300 mg, 1.2 mmol) was then added as a solid and the resulting mixture was stirred at RT for 18 h. The crude mixture was purified by preparative HPLC (ACN/water) to yield 60 mg (16%) of 8-fluoro-4-((2-(pyridin-3-yl)-1H-benzo[d]imidazol-1-yl)methyl)quinolin-2(1H)-one as a pale yellow. 1H NMR (400 MHz, DMSO-d6, TFA salt) delta 11.86 (s, 1H), 8.93 (s, 1H), 8.72 (d, 1H), 8.13 (d, 1H), 7.86 (d, 1H), 7.69 (d, 1H), 7.64 (d, 1H), 7.59-7.57 (m, 2H), 7.40-7.36 (m, 2H), 7.26 (m, 1H), 5.94 (s, 2H), 5.53 (s, 1H). LCMS: 371 (M+H)+.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 1137-67-3, 2-(Pyridin-3-yl)-1H-benzo[d]imidazole.

Reference:
Patent; KALYPSYS, INC.; US2008/139558; (2008); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C12H9N3

CdSO4·3/8 H2O (0.026 g, 0.1 mmol), 3PBI (0.0195 g, 0.1 mmol), NaOH (0.0072 g,0.18 mmol), adipic acid (0.0146 g, 0.1 mmol), and water (6 mL) were added to a 15-mLTeflon reactor and heated under autogenous pressure at 160 C for 3 days. The reaction mixture was cooled to room temperature at a rate of 5 C h-1. Yellow pellet crystals of 3suitable for X-ray diffraction analysis were obtained (0.0123 g, yield: 27% based onCdSO4). Elemental analysis Calcd (%) for C18H15Cd N3O5 (465.73): C, 46.38; H, 3.22; N,9.02; found: C, 46.19; H, 3.24; N, 9.05. IR (KBr, cm-1): 2943(w), 1557(s), 1419(s), 1329(m), 1278(m), 1197(m), 1130(w), 1049(m), 962(m), 930(m), 816(m), 740(s), 700(m), 637(m), 519(w), 428(m).

With the rapid development of chemical substances, we look forward to future research findings about 1137-67-3.

Reference:
Article; Wang, Cui-Cui; Wang, Jin-Hua; Tang, Gui-Mei; Wang, Yong-Tao; Cui, Yue-Zhi; Ng, Seik Weng; Journal of Coordination Chemistry; vol. 68; 21; (2015); p. 3918 – 3931;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 1137-67-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole. This compound has unique chemical properties. The synthetic route is as follows.

A reaction mixture of NiSO4·6H2O (0.0260 g, 0.1 mmol), 3PBI (0.0195 g, 0.1 mmol),NaOH (0.0072 g, 0.18 mmol), ADP (0.0146 g, 0.1 mmol), and water (6 mL) was added toa 15-mL Teflon reactor and heated under autogenous pressure at 160 C for 3 days. The reaction mixture was cooled to room temperature at a rate of 5 C h-1. Green pellet crystalsof 1 suitable for X-ray diffraction analysis were obtained (0.032 g, yield: 48.01% based on NiSO4). Elemental analysis Calcd (%) for C30H34NiN6O8 (665.34): C, 54.16; H, 5.15; N,12.63; found: C, 54.40; H, 5.17; N, 12.57; IR (KBr, cm-1): 3359(w), 3203(w), 2926(w),2220(br), 1552(s), 1448(m), 1404(s), 1313(s), 1286(m), 1286(m), 1226(m), 1195(m), 1128(m), 1055(w), 1028(w), 1001(w), 962(m), 735(s), 690(m), 432(m), 408(w).

According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.

Reference:
Article; Wang, Cui-Cui; Wang, Jin-Hua; Tang, Gui-Mei; Wang, Yong-Tao; Cui, Yue-Zhi; Ng, Seik Weng; Journal of Coordination Chemistry; vol. 68; 21; (2015); p. 3918 – 3931;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C12H9N3

CdSO4·3/8 H2O (0.026 g, 0.1 mmol), 3PBI (0.0195 g, 0.1 mmol), NaOH (0.0072 g,0.18 mmol), adipic acid (0.0146 g, 0.1 mmol), and water (6 mL) were added to a 15-mLTeflon reactor and heated under autogenous pressure at 160 C for 3 days. The reaction mixture was cooled to room temperature at a rate of 5 C h-1. Yellow pellet crystals of 3suitable for X-ray diffraction analysis were obtained (0.0123 g, yield: 27% based onCdSO4). Elemental analysis Calcd (%) for C18H15Cd N3O5 (465.73): C, 46.38; H, 3.22; N,9.02; found: C, 46.19; H, 3.24; N, 9.05. IR (KBr, cm-1): 2943(w), 1557(s), 1419(s), 1329(m), 1278(m), 1197(m), 1130(w), 1049(m), 962(m), 930(m), 816(m), 740(s), 700(m), 637(m), 519(w), 428(m).

With the rapid development of chemical substances, we look forward to future research findings about 1137-67-3.

Reference:
Article; Wang, Cui-Cui; Wang, Jin-Hua; Tang, Gui-Mei; Wang, Yong-Tao; Cui, Yue-Zhi; Ng, Seik Weng; Journal of Coordination Chemistry; vol. 68; 21; (2015); p. 3918 – 3931;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 1137-67-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole. This compound has unique chemical properties. The synthetic route is as follows.

A reaction mixture of NiSO4·6H2O (0.0260 g, 0.1 mmol), 3PBI (0.0195 g, 0.1 mmol),NaOH (0.0072 g, 0.18 mmol), ADP (0.0146 g, 0.1 mmol), and water (6 mL) was added toa 15-mL Teflon reactor and heated under autogenous pressure at 160 C for 3 days. The reaction mixture was cooled to room temperature at a rate of 5 C h-1. Green pellet crystalsof 1 suitable for X-ray diffraction analysis were obtained (0.032 g, yield: 48.01% based on NiSO4). Elemental analysis Calcd (%) for C30H34NiN6O8 (665.34): C, 54.16; H, 5.15; N,12.63; found: C, 54.40; H, 5.17; N, 12.57; IR (KBr, cm-1): 3359(w), 3203(w), 2926(w),2220(br), 1552(s), 1448(m), 1404(s), 1313(s), 1286(m), 1286(m), 1226(m), 1195(m), 1128(m), 1055(w), 1028(w), 1001(w), 962(m), 735(s), 690(m), 432(m), 408(w).

According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.

Reference:
Article; Wang, Cui-Cui; Wang, Jin-Hua; Tang, Gui-Mei; Wang, Yong-Tao; Cui, Yue-Zhi; Ng, Seik Weng; Journal of Coordination Chemistry; vol. 68; 21; (2015); p. 3918 – 3931;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Electric Literature of 1137-67-3, Adding some certain compound to certain chemical reactions, such as: 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole,molecular formula is C12H9N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1137-67-3.

, weighing 0.25g cobalt chloride hexahydrate,0.2 g of 2- (3-pyridyl) benzimidazole,0.2 g of 1,3-benzenedicarboxylic acid and 15 mL of water in a 50 mL flask,The flask was placed on a magnetic stirrer and stirred for 30 minutes.(2)The mixed homogeneous solution was transferred to a 25 mL autoclave.,The autoclave was placed in an oven,Heated from room temperature to 170 C at a rate of 1 C / min,At this temperature for 72h,And then to 5 / h rate down to room temperature,Solid-liquid separation is shown in Figure 1-3,The dinuclear cobalt complex shown in Figures 4-6,The yield was about 65%.

According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Heifei University; Zhang, Quanzheng; Cheng, Xuan; Ding, Dong; Chen, Ying; (13 pag.)CN103923126; (2016); B;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 1137-67-3, 2-(Pyridin-3-yl)-1H-benzo[d]imidazole, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 1137-67-3, blongs to pyridine-derivatives compound. Product Details of 1137-67-3

A reaction mixture of CdI2 (73.2 mg, 0.2 mmol), 3-PyBim (19.5 mg, 0.1 mmol), and water(10 ml) was added to a 15 ml Teon reactor under autogenous pressure at 160 C for 3 days and then cooled to room temperature at 5 C h-1. Pale yellow crystals of 1 suitable for diffraction analysis were obtained. (31 mg, Yield: 25.2%). Analysis found (%): C, 48.89; H, 3.50;N, 13.95; requires (%): C, 48.00; H, 3.52; N, 13.99; IR (KBr, cm-1): 3493 (m), 3169 (w), 3051 (w),3010 (w), 2993 (w), 2929 (w), 2887 (w), 2794 (w), 2717 (w), 2603 (w), 2189 (w), 1581 (m), 1483(m), 1433 (s), 1317 (m), 1280 (m), 1226 (m), 1192 (m), 1120 (m), 1047 (m), 966 (m), 923 (w),817 (m), 744 (s), 700 (m), 638 (m), 408 (w).

The synthetic route of 1137-67-3 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Wang, Jin-Hua; Tang, Gui-Mei; Qin, Ting-Xiao; Wang, Yong-Tao; Cui, Yue-Zhi; Ng, Seik Weng; Journal of Coordination Chemistry; vol. 70; 7; (2017); p. 1168 – 1189;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem