Category: 1137-67-3

Application of 1137-67-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole. This compound has unique chemical properties. The synthetic route is as follows.

General procedure: A reaction mixture of CdI2 (73.2 mg, 0.2 mmol), 3-PyBim (19.5 mg, 0.1 mmol), and water(10 ml) was added to a 15 ml Teon reactor under autogenous pressure at 160 C for 3 days and then cooled to room temperature at 5 C h-1. Pale yellow crystals of 1 suitable for diffraction analysis were obtained. (31 mg, Yield: 25.2%).

According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.

Reference:
Article; Wang, Jin-Hua; Tang, Gui-Mei; Qin, Ting-Xiao; Wang, Yong-Tao; Cui, Yue-Zhi; Ng, Seik Weng; Journal of Coordination Chemistry; vol. 70; 7; (2017); p. 1168 – 1189;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Related Products of 1137-67-3, Adding some certain compound to certain chemical reactions, such as: 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole,molecular formula is C12H9N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1137-67-3.

General procedure: To a stirred solution of 40 mg (0.18 mmol) of 2-[2-(pyridin-3-yl)ethyl]-1H-benzimidazole (2o) in N,N-dimethylformamide (5 mL) were added 71 mg (0.22 mmol) of 3-[4-(3-acetamidophenyl)piperidin-1-yl]propyl methanesulfonate (6) and 75 mg (0.54 mmol) of K2CO3. The reaction mixture was stirred at 80 C for 5 h. After cooling, water (50 mL) was added, and the mixture was extracted with ethylacetate (50 mL × 2). The organic layer was washed with brine, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (5% MeOH/CH2Cl2) to obtain the title compound (75 mg, 87%).

According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.

Reference:
Article; Lim, Chae Jo; Kim, Jeong Young; Lee, Byung Ho; Oh, Kwang-Seok; Yi, Kyu Yang; Bulletin of the Korean Chemical Society; vol. 34; 8; (2013); p. 2305 – 2310;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthetic Route of 1137-67-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole, molecular formula is C12H9N3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

General procedure: A solution of 2-(3-pyridyl)-1H-benzimidazole, L1, (0.34 g,1.79 mmol) in methanol (4 ml) was added to a solution ofZn(OAc)22H2O (0.39 g, 1.79 mmol) in methanol (6 ml).The mixture was stirred for 24 h at room temperature to give a white precipitate. After the reaction period, the precipitate was filtered off, washed with methanol (3 9 20 mL) and dried to afford complex 1 as a white solid.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1137-67-3, 2-(Pyridin-3-yl)-1H-benzo[d]imidazole.

Reference:
Article; Zaca, Thembisile P.; Ojwach, Stephen O.; Akerman, Matthew P.; Transition Metal Chemistry; vol. 41; 6; (2016); p. 663 – 673;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 1137-67-3, 2-(Pyridin-3-yl)-1H-benzo[d]imidazole, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C12H9N3, blongs to pyridine-derivatives compound. Formula: C12H9N3

A solution of 2-(3-pyridyl)-1H-benzimidazole, L1, (0.34 g,1.79 mmol) in methanol (4 ml) was added to a solution ofZn(OAc)22H2O (0.39 g, 1.79 mmol) in methanol (6 ml).The mixture was stirred for 24 h at room temperature to give a white precipitate. After the reaction period, the precipitate was filtered off, washed with methanol (3 9 20 mL) and dried to afford complex 1 as a white solid. Yield = 0.39 g (58 %). 1H NMR (400 MHz,DMSO-d6): d(ppm): 13.15 (s, 1H, NH), 9.45 (d, 1H, 3JHH = 7.19 Hz, ArH), 8.76 (d, 1H, 3JHH = 7.29 Hz,ArH), 8.54 (d, 1H, 3JHH = 7.29 Hz, ArH), 7.61 (d, 2H,3JHH = 7.19 Hz, ArH), 7.21 (d, 2H, 3JHH = 7.30 Hz,ArH), 1.80 (s, 6H, CH3). IR m (cm-1): 3074.87 (weak, N-H), 1625 (strong, C=O), 1601 (medium, C=Npy), 1445(weak, ArH). (ESI-MS) m/z (%): 194 (M?-Zn2C8H13O8-L1, 100 %); 314 (M?-ZnC6H13O6L1, 8.0 %), 501 (M?-ZnC7H12O6, 8.2 %), 501(M?-C4H12, 8.2 %). Anal. Calcd.for C16H15N3O4Zn: C, 50.75; H, 3.99; N, 10.00. Found: C,50.60; H, 3.70; N, 9.65.

The synthetic route of 1137-67-3 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Zaca, Thembisile P.; Ojwach, Stephen O.; Akerman, Matthew P.; Transition Metal Chemistry; vol. 41; 6; (2016); p. 663 – 673;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 1137-67-3, 2-(Pyridin-3-yl)-1H-benzo[d]imidazole, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 2-(Pyridin-3-yl)-1H-benzo[d]imidazole, blongs to pyridine-derivatives compound. Recommanded Product: 2-(Pyridin-3-yl)-1H-benzo[d]imidazole

A solution of CoCl2¢6H2O (0.25 g, 1.05 mmol), 3-PBIM(0.2 g, 1.03 mmol), 1,3-H2BDC (0.2 g, 1.2 mmol), and H2O(15 mL) was stirred under ambient condition. The mixturewas then sealed in a Teflon-lined steel vessel and heated at170C for three days. After slow cooling to room temperature, the resulting product was obtained (yield: 55%). Anal.Calcd. for C64H56Co2N12O14: C, 57.58; N, 12.59; H, 4.23%.Found: C, 58.13; N, 12.87; H, 4.54%. IR (KBr pellet, cm1):3450 s, 3050 s, 1870 m, 1615 s, 1565 w, 1535 m, 1500 m, 1478m, 1448 m, 1371 m, 1270 s, 1145 m, 1130 m, 1060 s, 1018 s,970 s, 880 m, 840 s, 770 m, 745 s, 705 m, 695 m, 593 m, 565 m.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1137-67-3, 2-(Pyridin-3-yl)-1H-benzo[d]imidazole, and friends who are interested can also refer to it.

Reference:
Article; Zhang, Quanzheng; Xia, Changkun; Lu, Hongdian; Jiang, Rui; Zhang, Xueke; Wang, Xinghan; He, Longzhong; Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry; vol. 46; 4; (2016); p. 543 – 547;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem