Category: 116383-98-3

HPLC of Formula: 116383-98-3On May 7, 1999 ,《Selective palladium-catalyzed carbonylations of dichloroquinoline and simple dichloropyridines》 appeared in Tetrahedron Letters. The author of the article were Najiba, Douja; Carpentier, Jean-Francois; Castanet, Yves; Biot, Christophe; Brocard, Jacques; Mortreux, Andre. The article conveys some information:

Dichloroquinoline and some dichloropyridines undergo selective alkoxycarbonylation in the presence of carbon monoxide, an alc. and PdCl2(PPh3)2 as a catalyst, affording chloro-monoester and/or diesters in good yields under selected reaction conditions. In addition to this study using Methyl 3-chloropicolinate, there are many other studies that have used Methyl 3-chloropicolinate(cas: 116383-98-3HPLC of Formula: 116383-98-3) was used in this study.

Methyl 3-chloropicolinate(cas: 116383-98-3) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.HPLC of Formula: 116383-98-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Category: pyridine-derivativesOn March 31, 1997, Epsztajn, J.; Plotka, M. W.; Grabowska, A. published an article in Synthetic Communications. The article was 《Application of organolithium compounds in organic synthesis. Part 19. Synthetic strategies based on aromatic metalation. A concise regiospecific synthesis of 3-halogenated picolinic and isonicotinic acids》. The article mentions the following:

The synthesis of the halogenated picolin- and isonicotinanilides I (R = Cl, Br, iodo, X = N, Y = CH; X = CH, Y = N) (II) via metalation (n-BuLi) of the anilides I (R = H) and then the reaction of the generated bis-lithiated anilides with halogenating agents (CCl3-CCl3, CH2Br-CH2Br, I2) followed by subsequent acidic hydrolysis of II, as a way of regiospecific transformation of picolinic and isonicotinic acids into their C3-halogenated derivatives, is described. In the experiment, the researchers used many compounds, for example, Methyl 3-chloropicolinate(cas: 116383-98-3Category: pyridine-derivatives)

Methyl 3-chloropicolinate(cas: 116383-98-3) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Albaneze-Walker, Jennifer; Bazaral, Charles; Leavey, Tanya; Dormer, Peter G.; Murry, Jerry A. published an article in Organic Letters. The title of the article was 《Improved Carbonylation of Heterocyclic Chlorides and Electronically Challenging Aryl Bromides》.HPLC of Formula: 116383-98-3 The author mentioned the following in the article:

Optimized conditions are described that effect the carbonylation of diverse heterocyclic chlorides to yield the desired alkyl esters. In addition, bromoanilines and bromoanisoles, which normally are poor substrates under standard carbonylation protocols, were efficiently converted to the desired products under these new conditions. The nature of the metal bidentate ligand complex was found to be critical Specifically, a correlation between ligand bite angle and catalytic efficiency is documented. In the part of experimental materials, we found many familiar compounds, such as Methyl 3-chloropicolinate(cas: 116383-98-3HPLC of Formula: 116383-98-3)

Methyl 3-chloropicolinate(cas: 116383-98-3) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.HPLC of Formula: 116383-98-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application In Synthesis of Methyl 3-chloropicolinateOn June 1, 2015, Kozlov, Maxim V.; Kleymenova, Alla A.; Romanova, Lyudmila I.; Konduktorov, Konstantin A.; Kamarova, Kamila A.; Smirnova, Olga A.; Prassolov, Vladimir S.; Kochetkov, Sergey N. published an article in Bioorganic & Medicinal Chemistry Letters. The article was 《Pyridine hydroxamic acids are specific anti-HCV agents affecting HDAC6》. The article mentions the following:

Recently we reported benzohydroxamic acids (BHAs) as potent and selective inhibitors of hepatitis C virus (HCV) replicon propagation. In this work 12 pyridine hydroxamic acids (PHAs) e. g., I, were synthesized and tested in full-genome replicon assay. It was found that PHAs possessed very similar anti-HCV properties compared to BHAs. Both classes of hydroxamic acids caused hyperacetylation of α-tubulin pointing to inhibition of histone deacetylase 6 (HDAC6) as part of their antiviral activity. The tested compounds did not inhibit the growth of poliovirus, displaying high selectivity against HCV. After reading the article, we found that the author used Methyl 3-chloropicolinate(cas: 116383-98-3Application In Synthesis of Methyl 3-chloropicolinate)

Methyl 3-chloropicolinate(cas: 116383-98-3) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Application In Synthesis of Methyl 3-chloropicolinate

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem