Category: 116986-13-1

Adding a certain compound to certain chemical reactions, such as: 116986-13-1, 3-(Bromomethyl)picolinonitrile, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 3-(Bromomethyl)picolinonitrile, blongs to pyridine-derivatives compound. Recommanded Product: 3-(Bromomethyl)picolinonitrile

Using General Procedure A: A solution of 3,3″-dimethyl-1′,2′,3′,4′,5′,6′-hexahydro-cis-[2,2′;6′,2″]terpyridine (0.104 g, 0.39 mmol), 3-bromomethyl-pyridine-2-carbonitrile (0.115 g, 0.58 mmol), KI (23 mg, 0.14 mmol), and DIPEA (0.15 mL, 0.86 mmol) in DMF (4 mL) was heated at 60 C. for 20 hours. Purification of the crude material by column chromatography on silica gel (20:1:1 CH2Cl2-CH3OH-NH4OH) provided 133 mg (88%) of 3-(3,3″-dimethyl-3′,4′,5′,6′-tetrahydro-2’H-cis-[2,2′;6′,2″]terpyridin-1′-ylmethyl)-pyridine-2-carbonitrile as a tan solid.

The synthetic route of 116986-13-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Chen, Gang; Crawford, Jason; Skerlj, Renato; US2005/154201; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 116986-13-1, name is 3-(Bromomethyl)picolinonitrile. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C7H5BrN2

Step 4: 2-{4-[2-(6, 7-DIFLUORO-QUINOLIN-2-YL)-ETHYL]-PHENOXYMETHYL}-BENZONITRILE. 1.0 G (5.0 mmol) of the compound from step 1,0. 077 G (0.5 MMOL) of sodium iodide, 1.6 G (5.0 MMOL) of caesium carbonate and 1.4 G (3.5 MMOL) of the previous compound in 23 ml of acetone are stirred at reflux temperature for 4. 5HR. Once cooled, the solids are filtered and the filtrate is concentrated giving 1.6 G (79 %) of a solid

With the rapid development of chemical substances, we look forward to future research findings about 116986-13-1.

Reference:
Patent; ALMIRALL PRODESFARMA S.A.; WO2004/43966; (2004); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem