Category: 123-03-5

Duklan, Neha; Chamoli, Pankaj; Raina, K. K.; Shukla, Ravi K. published the artcile< Dye dispersed lyotropic liquid crystals: Soft materials with high ionic conductivity and self-sustained adsorbents for dye sequestration>, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride, the main research area is cetylpyridinium chloride liquid crystal preparation dye sequestration adsorption.

Lyotropic liquid crystals phases are prepared from cationic surfactant (Cetylpyridinium chloride) in the aqueous medium. All the mixtures show well defined lamellar phases duly confirmed from X-ray diffraction and polarizing optical microscopy characterizations. Ionic conductivity of the lyotropic phases is ranging between 4.2 and 28.8 mS/cm and shows dependence on surfactant concentration Further, lamellar mesostructures are dispersed with cationic dye (methyl blue). We noticed that bilayer mesostructures act as an excellent adsorbent to sequester the cationic dye in the aqueous medium. Dye sequestration is confirmed visually and spectroscopically via UV-Visible characterization. Lyotropic adsorbents are found highly reactive as they sequester 0.01 wt% methyl blue dye within 30 min. Sequestration efficiency of lyotropic adsorbents is ranging from 98.9 to 87.5% (for 0.01 wt% dye). Considering electrostatic interactions, dye sequestration mechanisms are established and discussed. Our findings suggested that lyotropic adsorbents can be explored as a highly effective, reactive and cost-effective alternative for sequestration/adsorption of contaminations.

Inorganic Chemistry Communications published new progress about Adsorption. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yang, Cheng; Xie, Hao published the artcile< Multiple fluorescence response behaviours to proteins/bacteria and selective antibacterial activity of cetylpyridinium chloride (CPC)-based cationic carbon dots>, Formula: C21H38ClN, the main research area is fluorescence cetylpyridinium chloride cationic carbon dot.

Direct interaction between carbon dots (CDs) and biomols. leads to changes in the chem. and phys. status as well as properties of CDs, which can have various biol. and biomedical applications. In this work, the surface of CDs was modified with cetylpyridinium chloride (CPC) to facilitate interactions between CDs and biomols. Multiple fluorescence response behaviors of CPC-based CDs were observed towards several proteins (bovine serum albumin, lysozyme, protamine, and Hb) and bacterial cells (Escherichia coli and Staphylococcus aureus). Electrostatic attraction and hydrogen bonding were involved in inducing aggregation of CDs and fluorence enhancement. An inner filter effect might also occur to reduce fluorescence of CDs when interacting with proteins. Selective antibacterial activity of CPC-based CDs was observed towards Gram pos. bacterium Staphylococcus aureus. This work provides potential to develop CD-based techniques for detecting and visualizing proteins/bacteria as well as selective antibacterial agents towards Gram-pos. bacteria.

RSC Advances published new progress about Antibacterial agents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wang, Chih-Feng; Cheng, Zhihua; O’Callahan, Brian T.; Crampton, Kevin T.; Jones, Matthew R.; El-Khoury, Patrick Z. published the artcile< Tip-Enhanced Multipolar Raman Scattering>, Safety of 1-Hexadecylpyridin-1-ium chloride, the main research area is Tip Enhanced multipolar raman scattering; image thiobenzonitrile functionalized plasmonic gold nanocubes.

We record nanoscale chem. images of 4-thiobenzonitrile (TBN)-functionalized plasmonic gold nanocubes via tip-enhanced Raman spectroscopy (TERS). The spatially averaged optical response is dominated by conventional (dipolar) TERS scattering from TBN but also contains weaker spectral signatures in the 1225-1500 cm-1 region. The weak optical signatures dominate several of the recorded single-pixel TERS spectra. We can uniquely assign these Raman-forbidden transitions to multipolar Raman scattering, which implicates spatially varying enhanced elec. field gradients at plasmonic tip-sample nanojunctions. Specifically, we can assign observations of tip-enhanced elec. dipole-magnetic dipole as well as elec. dipole-elec. quadrupole driven transitions. Multipolar Raman scattering and local optical field gradients both need to be understood and accounted for in the interpretation of TERS spectral images, particularly in ongoing quests aimed at chem. reaction mapping via TERS.

Journal of Physical Chemistry Letters published new progress about Density functional theory (PBE). 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Safety of 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cadena, Myrna; Froenicke, Lutz; Britton, Monica; Settles, Matthew L.; Durbinjohnson, Blythe; Kumimoto, Emily; Gallardo, Rodrigo A.; Ferreiro, Aura; Chylkova, Tereza; Zhou, Huaijun; Pitesky, Maurice published the artcile< Transcriptome analysis of Salmonella heidelberg after exposure to cetylpyridinium chloride, acidified calcium hypochlorite, and peroxyacetic acid>, Formula: C21H38ClN, the main research area is transcriptome cetylpyridinium chloride calcium hypochlorite peroxyacetic acid Salmonella infection; Differential gene expression; Disinfectant; Poultry processing; RNA sequencing.

The application of RNA sequencing in com. poultry could facilitate a novel approach toward food safety with respect to identifying conditions in food production that mitigate transcription of genes associated with virulence and survivability. In this study, we evaluated the effects of disinfectant exposure on the transcriptomes of two field isolates of Salmonella Heidelberg (SH) isolated from a com. broiler processing plant in 1992 and 2014. The isolates were each exposed sep. to the following disinfectants commonly used in poultry processing: cetylpyridinium chloride (CPC), acidified calcium hypochlorite (aCH), and peroxyacetic acid (PAA). Exposure times were 8 s with CPC to simulate a poultry processing dipping station or 90 min with aCH and PAA to simulate the chiller tank in a poultry processing plant at 4°C. Based on comparison with a publicly available annotated SH reference genome with 5,088 genes, 90 genes were identified as associated with virulence, pathogenicity, and resistance (VPR). Of these 90 VPR genes, 9 (10.0%), 28 (31.1%), and 1 (1.1%) gene were upregulated in SH 2014 and 21 (23.3%), 26 (28.9%), and 2 (2.2%) genes were upregulated in SH 2014 challenged with CPC, aCH, and PAA, resp. This information and previously reported MICs for the three disinfectants with both SH isolates allow researchers to make more accurate recommendations regarding control methods of SH and public health considerations related to SH in food production facilities where SH has been isolated. For example, the MICs revealed that aCH is ineffective for SH inhibition at regulatory levels allowed for poultry processing and that aCH was ineffective for inhibiting SH growth and caused an upregulation of VPR genes.

Journal of Food Protection published new progress about Cell invasion. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lemaalem, M.; Ahfir, R.; Derouiche, A.; Filali, M. published the artcile< Static and dynamic properties of decane/water microemulsions stabilized by cetylpyridinium chloride cationic surfactant and octanol cosurfactant>, Electric Literature of 123-03-5, the main research area is decane water microemulsion stabilized cetylpyridinium chloride surfactant.

Mol. dynamics simulation (MD) is used to study the static and dynamic properties of pos. charged decane/water microemulsions, for various volume fractions φ (2.8%, 6.98%, 14%, and 26.5%). An effective hybrid potential combining three potentials, namely the hard-sphere repulsive potential, the van der Waals attractive potential, and the Yukawa repulsive potential, is used to describe the microemulsion interactions. The microemulsion shape is determined using the renormalized spectra in Porod representation. The appropriate potential parameters are tested using the Ornstein-Zernike integral equation approach with the Hypernetted Chain (HNC) closure relation by a comparison between the structure factor calculated from HNC and that obtained from Small Angle Neutron Scattering experiments (SANS). Thus, the micro arrangements of microemulsions have been analyzed using the pair correlation function g(r) and the structure factor S(q) obtained from HNC, SANS, and MD simulation using these parameters. The microemulsion dynamic properties were discussed using the mean-square displacement (MSD) and the diffusion coefficient Dc calculated from MD simulations.

RSC Advances published new progress about Biocompatible materials. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Electric Literature of 123-03-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wythe, L. A.; Dittoe, D. K.; Feye, K. M.; Olson, E. G.; Perry, L. M.; Ricke, S. C. published the artcile< Reduction of Salmonella Infantis on skin-on, bone-in chicken thighs by cetylpyridinium chloride application and the impact on the skin microbiota>, Application of C21H38ClN, the main research area is cetylpyridinium chloride chicken thigh Salmonella infantis skin microbiota; 16S rDNA; Salmonella Infantis; cetylpyridinium chloride; peroxyacetic acid; poultry.

Salmonella Infantis has been the etiol. agent of numerous foodborne outbreaks of nontyphoidal Salmonella. Consequently, there is an emergent need to mitigate Salmonella Infantis among poultry. Thus, this study evaluated the efficacy of cetylpyridinium chloride (CPC) vs. peroxyacetic acid (PAA), on bone-in, skin-on chicken thighs for the reduction of Salmonella and changes in the microbiota. Exactly 100 skin-on, bone-in chicken thighs (2 trials, 0 and 24 h, k = 5, n = 5, N = 50) were inoculated with 108 CFU/mL of a nalidixic acid resistant strain of S. Infantis for an attachment of 106 CFU/g. Thighs were treated with 20 s part dips (350 mL): a no inoculum, no treatment control (NINTC); no treatment control (NTC); tap water (TW); TW+CPC; TW+PAA. Following treatment, thighs were rinsed in 150 mL of nBPW, and rinsates were collected. Rinsates were spot plated for Salmonella and aerobic bacteria (APC). Log10 transformed counts were analyzed using a mixed-effects model (random effect = trial) with means separated using Tukey’s HSD (P ≤ 0.05). The genomic DNA of rinsates was extracted, and the 16S rDNA was sequenced on an Illumina MiSeq. Microbiota data were analyzed using QIIME2, with data considered significant at P ≤0.05 (main effects) and Q≤0.05 (pairwise differences). Treatment x time interactions were observed for both Salmonella and APC (P < 0.05). The treatment of thighs with PAA and CPC reduced Salmonella and APC in respect to the controls. Numerically, thighs treated with CPC had less Salmonella (4.29 log10CFU/g) and less APC (4.56log10CFU/g) at 24 h than all other treatments (P > 0.05). Differences in diversity metrics were not consistently observed between treatments; however, in trial 2, the NTC treated thighs were different than those treated with CPC (P < 0.05; Q < 0.05). In both trials, ANCOM, the anal. of microbiome compositional profiles, revealed shifts at both the phylum and order levels with thighs being different in the relative abundances of Proteobacteria (P < 0.05). In conclusion, treatment of skin-on poultry parts with CPC may reduce the risk of foodborne outbreaks caused by Salmonella Infantis. Poultry Science published new progress about Acidobacteria. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Application of C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Jevremovic, Anka; Bozinovic, Nevena; Arsenijevic, Dragana; Marmakov, Sanal; Nedic Vasiljevic, Bojana; Uskokovic-Markovic, Snezana; Bajuk-Bogdanovic, Danica; Milojevic-Rakic, Maja published the artcile< Modulation of cytotoxicity by consecutive adsorption of tannic acid and pesticides on surfactant functionalized zeolites>, Formula: C21H38ClN, the main research area is tannic acid pesticide zeolite adsorption cytotoxicity.

This study investigated the environmental application of FAU type zeolites modified with cationic surfactants (cetylpyridinium chloride, tetrapropylammonium chloride and benzalkonium chloride). Adsorbent characterization was conducted using Fourier-transform IR and Raman spectroscopy, thermogravimetry and DTA, at. force microscopy and X-ray powder diffraction. The efficiency for tannic acid adsorption from aqueous solution on the surface of prepared composites is studied and the adsorption process was modelled with different isotherm equations. Surfactant modifications of zeolites led to improved adsorption properties compared to FAU zeolites alone. The proposed mechanism controlling the adsorption of tannic acid onto surfactant modified zeolites mainly relies on π-π and hydrophobic interactions. The investigated materials are promising adsorbents for tannic acid and similar phenolics and may be important for environmental and dietary aspects of polyphenol persistence and usage. Further on, functionalized zeolites were studied for insecticide acetamiprid removal, prior to and after tannic acid retention. Promising findings of insecticide co-adsorption with tannic acid led to cytotoxicity evaluation. The cytotoxicity modulation effect of zeolites and tannic acid on acetamiprid points to the essential role of both components in insecticide toxicity reduction

Environmental Science: Processes & Impacts published new progress about Adsorption. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lee, Johnny Ching-Wei; Porcar, Lionel; Rogers, Simon A. published the artcile< Unveiling temporal nonlinear structure-rheology relationships under dynamic shearing>, COA of Formula: C21H38ClN, the main research area is micelle nonlinear rheol dynamic shearing; LAOS; nonlinear rheology; polymer rheology; rheo SANS; structure–rheology relationship; viscoelastic; worm-like micelles.

Understanding how microscopic rearrangements manifest in macroscopic flow responses is one of the central goals of nonlinear rheol. studies. Using the sequence-of-phys.-processes framework, we present a natural 3D structure-rheol. space that temporally correlates the structural and nonlinear viscoelastic parameters. Exploiting the rheo-small-angle neutron scattering (rheo-SANS) techniques, we demonstrate the use of the framework with a model system of polymer-like micelles (PLMs), where we unveil a sequence of microscopic events that micelles experience under dynamic shearing across a range of frequencies. The least-aligned state of the PLMs is observed to migrate from the total strain extreme toward zero strain with increasing frequency. Our proposed 3D space is generic, and can be equally applied to other soft materials under any sort of deformation, such as startup shear or uniaxial extension. This work therefore provides a natural approach for researchers to study complex out-of-equilibrium structure-rheol. relationships of soft materials.

Polymers (Basel, Switzerland) published new progress about Linear viscoelasticity. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, COA of Formula: C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bahmani, Pegah; Maleki, Afshin; Rezaee, Reza; Mahvi, Amir Hossein; Khamforoush, Mehrdad; Dehestani Athar, Saeed; Daraei, Hiua; Gharibi, Fardin; McKay, Gordon published the artcile< Arsenate removal from aqueous solutions using micellar-enhanced ultrafiltration>, Quality Control of 123-03-5, the main research area is arsenate wastewater treatment micellar enhanced ultrafiltration; Arsenate removal; Micelle optimization; Polyacrylonitrile membrane; Surfactant enhancement; Ultrafiltration.

In this study, arsenate (As-V) removal using micellar enhanced ultrafiltration (MEUF) modified by cationic surfactants was studied by a dead-end polyacrylonitrile (PAN) membrane apparatus The UF membrane has been produced by a phase inversion process. The prepared membrane was characterized and analyzed for morphol. and membrane properties. The influence of operating parameters such as initial concentrations of As-V, surfactants, pH, membrane thickness, and co-existing anions on the removal of As-V, surfactant rejection, and permeate flux have been studied. The exptl. results show that from the two different cationic surfactants used the CPC (cetyl-pyridinium chloride) efficiency (91.7%) was higher than that of HTAB (hexadecyltrimethyl-ammonium bromide) (83.7%). The highest As-V removal was 100%, and was achieved using initial feed concentrations of 100-1000μg/L, at pH 7 with a membrane thickness of 150μm in a dead-end filtration system. This efficiency for As-V removal was similar to that obtained using a cross-flow system. Nevertheless, this flux reduction was less than the reduction achieved in the dead-end filtration process. The PAN fabricated membrane in comparison to the RO and NF processes selectively removed the arsenic and the anions, in the water taken from the well, and had no substantial effect on the cations.

Journal of Environmental Health Science and Engineering published new progress about Cationic surfactants. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Quality Control of 123-03-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Seo, Hyun Wook; Seo, Joon Pyung; Cho, Yuri; Ko, Eunkyong; Kim, Yoon Jun; Jung, Guhung published the artcile< Cetylpyridinium chloride interaction with the hepatitis B virus core protein inhibits capsid assembly>, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride, the main research area is cetylpyridinium chloride hepatitis virus protein capsid assembly; Antiviral; Capsid assembly inhibitor; Cetylpyridinium chloride (CPC); Drug synergism; Hepatitis B virus (HBV).

Hepatitis B virus (HBV) infection is a major risk factor for chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC) worldwide. While multiple hepatitis B drugs have been developed, build up of drug resistance during treatment or weak efficacies observed in some cases have limited their application. Therefore, there is an urgent need to develop substitutional pharmacol. agents for HBV-infected individuals. Here, we identified cetylpyridinium chloride (CPC) as a novel inhibitor of HBV. Using computational docking of CPC to core protein, microscale thermophoresis anal. of CPC binding to viral nucleocapsids, and in vitro nucleocapsid formation assays, we found that CPC interacts with dimeric viral nucleocapsid protein (known as core protein or HBcAg) specifically. Compared with other HBV inhibitors, such as benzenesulfonamide (BS) and sulfanilamide (SA), CPC achieved significantly better reduction of HBV particle number in HepG2.2.15 cell line, a derivative of human HCC cells that stably expresses HBV. CPC also inhibited HBV replication in mouse hydrodynamic model system. Taken together, our results show that CPC inhibits capsid assembly and leads to reduced HBV biogenesis. Thus, CPC is an effective pharmacol. agent that can reduce HBV particles.

Virus Research published new progress about Animal gene, CYP2D6 Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem