Electric Literature of 126832-81-3, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 126832-81-3 as follows.
27c) 1-(4-Pyridyl)-4-piperidone Hydrazone Hydrazine monohydrate (1 ml) was added to a solution of 1-(4-pyridyl)-4-piperidone (1.76 g) in methanol (18 ml), and the mixture was stirred at room temperature for 1 hour. The solvent was distilled off, and the residue was crystallized with methanol-ether to obtain the title compound as pale yellow crystals (1.76 g, 92%). NMR (CDCl3) delta: 2.50 (2H, t, J=6.2), 2.61 (2H, t, J=6.2), 3.54 (2H, t, J=6.2), 3.63 (2H, t, J=6.2), 4.99 (2H, bs), 6.60 (2H, d, J=6.6), 8.27 (2H, d, J=6.6).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,126832-81-3, its application will become more common.
Reference:
Patent; Kubo, Keiji; Miyawaki, Toshio; Kawamura, Masaki; US2003/187023; (2003); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem