Category: 13362-78-2

Synthetic Route of 13362-78-2 , The common heterocyclic compound, 13362-78-2, name is (E)-1,2-Di(pyridin-4-yl)ethene, molecular formula is C12H10N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: To a stirred solution of HL (95.6mg, 0.4mmol) in absolute EtOH (10ml), solid Zn(OAc)2·2H2O (43.9mg, 0.2mmol) and absolute bpe (trans-1,2-bis(4-pyridyl)ethylene, 18mg, 0.1mmol) were added separately, and the final mixture was heated under reflux for 5h. A solution of Ln(NO3)3·6H2O (0.2mmol, Ln=Nd, 0.087g; Ln=Yb, 0.089g; Ln=Er, 0.088g; Ln=Gd, 0.090g) in absolute MeCN (20ml) were added sequentially. Then the mixture was refluxed for another 3h. The respective yellow clear solution was then cooled to room temperature and filtered. Diethyl ether was allowed to diffuse slowly into the respective solution at room temperature and pale yellow microcrystallines 5?8 were obtained in about three weeks, respectively.

The synthetic route of 13362-78-2 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Zhang, Zhao; Feng, Weixu; Su, Peiyang; Liu, Han; Zhang, Yao; Wang, Zheng; Miao, Tiezheng; Lue, Xingqiang; Fan, Daidi; Wong, Wai-Kwok; Jones, Richard A.; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 116; (2013); p. 102 – 110;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of 13362-78-2 , The common heterocyclic compound, 13362-78-2, name is (E)-1,2-Di(pyridin-4-yl)ethene, molecular formula is C12H10N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

A mixture of (E)-1,2-di(4-pyridyl)ethylene (91 mg, 0.5 mmol) and sodium 2-bromoethanesulfonate (317 mg, 1.5 mmol) (Aldrich) in abs. EtOH (3 mL) was refluxed with stirring for 50 h. The insoluble substance was filtered, washed with benzene, MeOH, and acetone, and re-crystallized from water-EtOH (2.8:1 (v/v), 2.7 mL) to yield 128 mg (64percent) of (E)-3a as a pinkish powder.

The synthetic route of 13362-78-2 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Vedernikov, Artem I.; Lobova, Natalia A.; Kuz’mina, Lyudmila G.; Howard, Judith A.K.; Strelenko, Yuri A.; Alfimov, Michael V.; Gromov, Sergey P.; Journal of Molecular Structure; vol. 989; 1-3; (2011); p. 114 – 121;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 13362-78-2, name is (E)-1,2-Di(pyridin-4-yl)ethene, molecular formula is C12H10N2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. COA of Formula: C12H10N2

General procedure: Equimolar amounts of 1,10-diiodoperfluorodecane (1e) and dipyridyl 2a or its ethylene analogue 2b were dissolved in a vial containing chloroform at room temperature and in a vial. The open vial was closed in a cylindrical bottle containing paraffin oil. Chloroform was allowed to diffuse at room temperature and after two days 1e·2a,b were isolated as white crystals, washed with n-pentane, and characterized.

With the rapid development of chemical substances, we look forward to future research findings about 13362-78-2.

Reference:
Article; Catalano, Luca; Metrangolo, Pierangelo; Pilati, Tullio; Resnati, Giuseppe; Terraneo, Giancarlo; Ursini, Maurizio; Journal of Fluorine Chemistry; vol. 196; (2017); p. 32 – 36;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 13362-78-2, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 13362-78-2 as follows.

A mixture of ZnSO4* 7H2O (0.05mmol, 0.010g), H2L (0.025mmol ,0.006g), DPE (0.025mmol 0.005g), NaOH (0.025mmol,0.001g) and H2O (8mL) was sealed in a Teflon-lined autoclave and heated at 120 °C for 3 days,then followed by slow cooling to room temperature. The yield of the colorless block crystals is ca.68percent based on H2L. Elemental Anal. Found:C, 55.8;H,3.5;N,8.1percent. Calcd. for ZnC25H21N3O7: C,55.5;H,3.9;N,7.8percent. IR(cm1) (seeFig.S1): 3325(s),3061(m),1637(s),1568(s),1418(m),1387(s),1336(m),1281(m),1194(s),1148(w),1037(m),1017(m),964(m),842(s),769(m),671(m),549(s),462(m).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13362-78-2, its application will become more common.

Reference:
Article; Yan, Xingxiu; Qiu, Xiandeng; Yan, Zhishuo; Li, Hongjiang; Gong, Yun; Lin, Jianhua; Journal of Solid State Chemistry; vol. 237; (2016); p. 313 – 322;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 13362-78-2, (E)-1,2-Di(pyridin-4-yl)ethene, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 13362-78-2, blongs to pyridine-derivatives compound. HPLC of Formula: C12H10N2

A mixture of (E)-1,2-di(4-pyridyl)ethylene (91 mg, 0.5 mmol) and 1,4-butanesultone (204 mg, 1.5 mmol) (Aldrich) was heated at 140 °C (oil bath) for 40 h. The resulting mass was refluxed with benzene (~15 mL) for 2 h, filtered, washed with benzene and acetone, and re-crystallized from water-EtOH (2.5:1 (v/v), 1.4 mL) to yield 184 mg (81percent) (E)-3c as a white powder.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13362-78-2, its application will become more common.

Reference:
Article; Vedernikov, Artem I.; Lobova, Natalia A.; Kuz’mina, Lyudmila G.; Howard, Judith A.K.; Strelenko, Yuri A.; Alfimov, Michael V.; Gromov, Sergey P.; Journal of Molecular Structure; vol. 989; 1-3; (2011); p. 114 – 121;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 13362-78-2, (E)-1,2-Di(pyridin-4-yl)ethene, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C12H10N2, blongs to pyridine-derivatives compound. Formula: C12H10N2

A mixture of Zn(NO3)26H2O (0.3 g, 1 mmol), H3tris (0.24 g,2 mmol), and bis(4-pyridyl)ethylene (0.18 g, 1 mmol) inmethanol (20 mL) was sealed in a Teflon-lined stainless steelcontainer and heated at 110 C for 30 hours, then slowlycooled to room temperature. The resulted yellow crystals werewashed with methanol and dried in air. Yield: 68percent.

The synthetic route of 13362-78-2 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Cucos, Andrei; Paraschiv, Carmen; Shova, Sergiu; Madalan, Augustin; Sbarcea, Gabriela; Marinescu, Virgil; Andruh, Marius; Revue Roumaine de Chimie; vol. 60; 10; (2015); p. 1005 – 1013;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.13362-78-2, name is (E)-1,2-Di(pyridin-4-yl)ethene, molecular formula is C12H10N2, molecular weight is 182.22, as common compound, the synthetic route is as follows.HPLC of Formula: C12H10N2

A mixture of ZnCl2(20 mg, 0.147 mmol), H4L(12 mg,0.02 mmol), dpe (9 mg, 0.05 mmol), CH3CN(2 mL),water (1 mL) and HCl (150muL of 6 mol/L) was sealed in an autoclave equipped with a Teflon liner (25 mL). The mixture was heated at 120 °C for 3 days, then cooled to roomtemperature. Colorless rod-shaped crystals of 2 were collected in ca. 32percent yield based on H4L. Elemental analysis for C114H92N8O28Zn4,calcd (percent): C, 59.96; H, 4.06; N, 4.91.Found (percent): C, 59.02; H, 4.17; N, 4.83. IR data (KBr, cm?1):3417 (s), 2360 (w), 2068 (w), 1672 (s), 1613 (s), 1560 (m), 1504 (m), 1430 (s), 1303 (m), 1228 (m), 1127 (s), 1072 (s),1026 (s), 976 (s), 844 (s), 616 (m), 569 (s), 548 (s), 511 (w).

At the same time, in my other blogs, there are other synthetic methods of this type of compound,13362-78-2, (E)-1,2-Di(pyridin-4-yl)ethene, and friends who are interested can also refer to it.

Reference:
Article; Wei, Jia; Zhou, Ting; Zuo, Yuxiang; Cheng, Wei-Wei; Liu, Mei-Pin; Bian, Rong-Rong; Chen, Ning-Ning; Xue, Yun-Shan; Tao, Jian-Qing; Transition Metal Chemistry; vol. 43; 6; (2018); p. 529 – 537;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chemistry is an experimental science, COA of Formula: C12H10N2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 13362-78-2, Name is (E)-1,2-Di(pyridin-4-yl)ethene, molecular formula is C12H10N2, belongs to pyridine-derivatives compound. In a document, author is Duan, Jindian.

Copper-Catalyzed [3+2] Annulation of 2-Arylidene-1,3-Indandiones with N-Acetyl Enamides for the Synthesis of Spiropyrrolines

A copper-catalyzed intermolecular [3+2] annulation of 2-arylidene-1,3-indandiones with N-acetyl enamides has been developed to assemble spirocyclic pyrrolines, which are important building blocks for organic synthesis and drug discovery. This heteroannulation protocol tolerates various functional groups and proceeds in good to excellent yields. Mechanistic studies reveal that the reactions might involve radical processes. 1-Pyrrolines are important core structural constituents of numerous naturally occurring compounds and pharmaceuticals.([1]) On the other hand, spiroindane-1,3-diones have been the focus of considerable attention due to their prevalence in many natural products that possess varied and extensive biological activities, which include antitumor, antibiotic,([2]) and antiproliferative activity on HL60 and apoptosis resistant leukemia cell lines. Accordingly, a number of synthetic strategies have been investigated to construct these skeletons. Considering the biomedical importance of the two classes of compounds, the introduction of spiroindane-1,3-dione group into the pyrroline core structure may further broaden the utilization of these compounds and potentially benefit drug-discovery efforts.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 13362-78-2, in my other articles. COA of Formula: C12H10N2.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 13362-78-2, Name is (E)-1,2-Di(pyridin-4-yl)ethene, molecular formula is C12H10N2. In an article, author is Bruch, Quinton J.,once mentioned of 13362-78-2, Name: (E)-1,2-Di(pyridin-4-yl)ethene.

Dinitrogen Reduction to Ammonium at Rhenium Utilizing Light and Proton-Coupled Electron Transfer

The direct scission of the triple bond of dinitrogen (N-2) by a metal complex is an alluring entry point into the transformation of N-2 to ammonia (NH3) in molecular catalysis. Reported herein is a pincer-ligated rhenium system that reduces N-2 to NH3 via a well-defined reaction sequence involving reductive formation of a bridging N-2 complex, photolytic N-2 splitting, and proton-coupled electron transfer (PCET) reduction of the metal nitride bond. The new complex (PONOP)ReCl3 (PONOP = 2,6-bis(diisopropylphosphinito)pyridine) is reduced under N-2 to afford the trans,trans-isomer of the bimetallic complex RPONOP)ReCl2](2)(mu-N-2) as an isolable kinetic product that isomerizes sequentially upon heating into the trans,cis and cis,cis isomers. All isomers are inert to thermal N-2 scission, and the trans,trans-isomer is also inert to photolytic N-2 cleavage. In striking contrast, illumination of the trans,cis and cis,cis-isomers with blue light (405 nm) affords the octahedral nitride complex cis-(PONOP)Re(N)Cl-2 in 47% spectroscopic yield and 11% quantum yield. The photon energy drives an N-2 splitting reaction that is thermodynamically unfavorable under standard conditions, producing a nitrido complex that reacts with SmI2/H2O to produce a rhenium tetrahydride complex (38% yield) and furnish ammonia in 74% yield.

Interested yet? Keep reading other articles of 13362-78-2, you can contact me at any time and look forward to more communication. Name: (E)-1,2-Di(pyridin-4-yl)ethene.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Synthetic Route of 13362-78-2, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 13362-78-2, Name is (E)-1,2-Di(pyridin-4-yl)ethene, SMILES is C1(/C=C/C2=CC=NC=C2)=CC=NC=C1, belongs to pyridine-derivatives compound. In a article, author is Olaru, Marian, introduce new discover of the category.

Tri- and Tetranuclear Metal-String Complexes with Metallophilic d(10)-d(10) Interactions

The reaction of 2,6-F2C6H3SiMe3 with Ph2PLi provided 2,6-(Ph2P)(2)C6H3SiMe3 (1), which can be regarded as precursor for the novel anionic tridentate ligand [2,6-(Ph2P)(2)C6H3](-) (PCP)(-). The reaction of 1 with [AuCl(tht)] (tht=tetrahydrothiophene) afforded 2,6-(Ph2PAuCl)(2)C6H3SiMe3 (2). The subsequent reaction of 2 with CsF proceeded with elimination of Me3SiF and yielded the neutral tetranuclear complex linear-[Au4Cl2(PCP)(2)] (3) comprising a string-like arrangement of four Au atoms. Upon chloride abstraction from 3 with NaBAr4F (Ar-F=3,5-(CF3)(2)C6H3) in the presence of tht, the formation of the dicationic tetranuclear complex linear-[Au-4(PCP)(2)(tht)(2)](BAr4F)(2) (4) was observed, in which the string-like structural motif is retained. Irradiation of 4 with UV light triggered a facile rearrangement in solution giving rise to the dicationic tetranuclear complex cyclo-[Au-4(PCP)(2)(tht)(2)](BAr4F) (5), which comprises a rhomboidal motif of four Au atoms. In 3-5, the Au atoms are associated by a number of significant aurophilic interactions. The atom-economic and selective reaction of 3 with HgCl2 yielded the neutral trinuclear bimetallic complex [HgAu2Cl3(PCP)] (6) comprising significant metallophilic interactions between the Au and Hg atoms. Therefore, 6 may be also regarded as a metallopincer complex [ClHg(AuCAu)] between Hg-II and the anionic tridentate ligand [2,6-(Ph2PAuCl)(2)C6H3](-) (AuCAu)(-) containing a central carbanionic binding site and two gold-arms contributing pincer-type chelation trough metallophilic interactions. Compounds 1-6 were characterized experimentally by multinuclear NMR spectroscopy and X-ray crystallography and computationally using a set of real-space bond indicators (RSBIs) derived from electron density (ED) methods including Atoms In Molecules (AIM), the Electron Localizability Indicator (ELI-D) as well as the Non-Covalent Interaction (NCI) Index.

Synthetic Route of 13362-78-2, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 13362-78-2 is helpful to your research.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem