13472-83-8, Adding a certain compound to certain chemical reactions, such as: 13472-83-8, 2-Methoxypyridin-3-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 13472-83-8, blongs to pyridine-derivatives compound.
The starting material can be obtained as follows: A mixture of 15.4 g of 3-hydroxy-2-methoxy-pyridine, 16 g of potassium carbonate, 25 ml of epichlorohydrin and 150 ml of acetonitrile is refluxed for 7 hours. Cooling and filtering the mixture and evaporating the filtrate yields crude 3-(2,3-epoxy-propoxy)-2-methoxypyridine, which is used without further purification. In an analogous manner, 1-{1-[2-hydroxy-3-(2-methoxy-6-methyl-3-pyridyloxy)-propyl]-4-piperidyl}-imidazolidin-2-one, which after recrystallisation from a mixture of methylene chloride and diethyl ether melts at 144-147, can be obtained by reacting 20 g of crude 3-(2,3-epoxy-propoxy)-2-methoxy-6-methyl-pyridine and 16.5 g of 1-(4-piperidyl)-imidazolidin-2-one.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13472-83-8, its application will become more common.
Reference:
Patent; Ciba-Geigy Corporation; US4264599; (1981); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem