Category: 13600-42-5

Reference of 13600-42-5, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 13600-42-5 as follows.

500 mL round bottom flask, 79.6 g (330 mmo 1) of 2,6-dichloro-3-cyano-4-(trifluoromethyl)pyridine concentrated sulfuric acid 400 grams heated to 100 degrees with stirring l h, after the reaction was added to the water to precipitate a solid, filtered and washed, dried to give a white solid 77 grams, yield 90.09%.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13600-42-5, its application will become more common.

Reference:
Patent; Hebei Lan Tai Chemical Technology Co., Ltd.; Guo Ming; Meng Shuiqiang; Tian Penghui; Hou Jianjun; (14 pag.)CN107382848; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 13600-42-5, 2,6-Dichloro-4-(trifluoromethyl)nicotinonitrile, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 13600-42-5, blongs to pyridine-derivatives compound. category: pyridine-derivatives

(1) 11.3 g of 3-cyano-2,6-dichloro-4-trifluoromethylpyridine was gradually added to 22.6 ml of concentrated sulfuric acid, and then the mixture was heated and reacted at 100 C. for one hour. After completion of the reaction, the mixture was poured into ice water, whereupon white precipitates formed. The precipitates were collected by filtration, and the filtrate was extracted with methylene chloride. The organic layer was dried over anhydrous sodium sulfate, and then the solvent was distilled off under reduced pressure to obtain a white solid. This solid and the precipitates previously obtained, were put together to obtain 9.2 g of 2,6-dichloro-4-trifluoromethyl-3-pyridine carboxamide.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13600-42-5, its application will become more common.

Reference:
Patent; Ishihara Sangyo Kaisha Ltd.; US5360806; (1994); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem