Category: 141-86-6

《Synthesis, characterization, DNA interaction and docking studies of novel Schiff base ligand derived from 2,6-diaminopyridine and its complexes》 was written by Kurt, Baris; Temel, Hamdi; Atlan, Metin; Kaya, Savas. Category: pyridine-derivativesThis research focused ontransition metal Schiff diaminopyridine hydroxynaphthalenylmethylideneaminophenylethanone complex preparation thermal stability; magnetic susceptibility DNA binding transition metal Schiff diaminopyridine hydroxynaphthalenylmethylideneaminophenylethanone. The article conveys some information:

In this study 1-(4-{[(3-hydroxynaphthalen-2-yl)methylidene]amino}phenyl)ethan-1-one (B1 ligand) were synthesized from the reaction of 2-hydroxy-1-naphthaldehyde with 4-amino-acetophenone. Following that 1-(N-{4-[(1)-1-({6-[(Z)-[1-(4-{[(3- hydroxynaphthalen-2-yl) methylidene]amino}phenyl)ethylidene]amino]pyridin-2- yl}imino)ethyl]phenyl}carboximidoyl)naphthalen-2-ol (L1 ligand) were synthesized from the reaction of 2,6-diamino pyridine with B1 ligand. Using this Schiff base ligand Cu(II), Fe(II) and Pd(II) complexes were prepared The structure of the ligand and its complexes were determined by 1H NMR, FTIR, UV-Vis, elemental anal., thermal analyses and magnetic susceptibility spectral data. Further, DNA binding properties of the ligand and its metal complexes were investigated and docking studies were carried out. As a result ligands and copper complex showed DNA binding activity and an increase with H2O2. According to these results it can be suggested that these compounds are very suitable drug candidates. The results came from multiple reactions, including the reaction of 2,6-Diaminopyridine(cas: 141-86-6Category: pyridine-derivatives)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Journal of Separation Science included an article by Jadda, Ramana; Madhumanchi, Sreenu; Suedee, Roongnapa. Product Details of 141-86-6. The article was titled 《Novel adsorptive materials by adenosine 5′-triphosphate imprinted-polymer over the surface of polystyrene nanospheres for selective separation of adenosine 5′-triphosphate biomarker from urine》. The information in the text is summarized as follows:

The authors have developed a method to assess ATP by adsorptive extraction using surface ATP-imprinted polymer over polystyrene nanoparticles (412 ± 16 nm) for selective recognition/separation from urine. Molecularly imprinted polymer was synthesized by emulsion copolymerization reaction using ATP as a template, functional monomers (methacrylic acid, N-iso-Pr acrylamide, and dimethylamino ethylmethacrylate) and a crosslinker, methylenebisacrylamide. The binding capacities of imprinted and non-imprinted polymers were measured using HPLC with UV detection with a detection limit of 1.6 ± 0.02μM of ATP in the urine. High binding affinity (QMIP, 42.65μmol/g), and high selectivity and specificity to ATP compared to other competitive nucleotides including ADP, AMP, and analogs such as adenosine, adenine, uridine, uric acid, and creatinine were observed The imprinting efficiency of imprinted polymer is 2.11 for urine (QMIP, 100.3μmol/g) and 2.51 for synthetic urine (QMIP, 48.5μmol/g). The extraction protocol was successfully applied to the direct extraction of ATP from spiked human urine indicating that this synthesized molecularly imprinted polymer allowed ATP to be preconcd. while simultaneously interfering compounds were removed from the matrix. These submicron imprinted polymers over nano polystyrene spheres have a potential in the pharmaceutical industries and clin. anal. applications. In the part of experimental materials, we found many familiar compounds, such as 2,6-Diaminopyridine(cas: 141-86-6Product Details of 141-86-6)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Product Details of 141-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Chen, Guangbo; An, Yun; Liu, Shengwen; Sun, Fanfei; Qi, Haoyuan; Wu, Haofei; He, Yanghua; Liu, Pan; Shi, Run; Zhang, Jian; Kuc, Agnieszka; Kaiser, Ute; Zhang, Tierui; Heine, Thomas; Wu, Gang; Feng, Xinliang published an article in Energy & Environmental Science. The title of the article was 《Highly accessible and dense surface single metal FeN4 active sites for promoting the oxygen reduction reaction》.Recommanded Product: 141-86-6 The author mentioned the following in the article:

Single iron atom and nitrogen-codoped carbon (Fe-N-C) electrocatalysts, which have great potential to catalyze the kinetically sluggish oxygen reduction reaction (ORR), have been recognized as the most promising alternatives to the precious metal platinum. Unfortunately, the ORR properties of the existing Fe-N-C catalysts are significantly hampered by the inferior accessibility and intrinsic activity of FeN4 moieties. Here, we constructed densely exposed surface FeN4 moieties on a hierarchically porous carbon (sur-FeN4-HPC) by Fe ion anchoring and a subsequent pyrolysis strategy using the nitrogen-doped hierarchically porous carbon (NHPC) as the scaffold. The high surface area of the NHPC with abundant surface Fe anchoring sites enabled the successful fabrication of densely accessible FeN4 active moieties (34.7 x 1019 sites g-1) on sur-FeN4-HPC. First-principles calculations further suggested that the edge effect could regulate the electronic structure of the single Fe site, hence promoting the intrinsic ORR activity of the FeN4 moiety. As a result, the sur-FeN4-HPC electrocatalyst exhibited excellent ORR activity in acidic media with a high half-wave potential of 0.83 V (vs. the reversible hydrogen electrode). We further examined sur-FeN4-HPC as a cathode catalyst in proton exchange membrane fuel cells (PEMFCs). The membrane electrode assembly delivered a high c.d. of 24.2 mA cm-2 at 0.9 ViR-free (internal resistance-compensated voltage) under 1.0 bar O2 and a maximum peak power d. of 0.412 W cm-2 under 1.0 bar air. Importantly, the catalyst demonstrated promising durability during 30 000 voltage cycles under harsh H2 and air conditions. The PEMFC performance of sur-FeN4-HPC outperforms those of the previously reported Fe-N-C electrocatalysts. The engineering of highly accessible and dense surface FeN4 sites on sur-FeN4-HPC offers a fruitful pathway for designing high-performance electrocatalysts for different electrochem. processes. In the experiment, the researchers used many compounds, for example, 2,6-Diaminopyridine(cas: 141-86-6Recommanded Product: 141-86-6)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Recommanded Product: 141-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Zhang, Boaiqi; Liu, Fuyang; Nie, Chenyi; Hou, Yanghui; Tong, Meiping published an article in Journal of Hazardous Materials. The title of the article was 《Photocatalytic degradation of paracetamol and bisphenol A by chitosan supported covalent organic framework thin film with visible light irradiation》.Electric Literature of C5H7N3 The author mentioned the following in the article:

Covalent Organic Frameworks (COFs) have attracted extensive attention for the photocatalytic degradation of emerging organic contaminants. The difficulty in separation and recovery after use yet would hinder the practical application of COFs in powder form. In present study, COFs in film form were fabricated via using chitosan as the film-substrate to support COFs (CSCF). We found that CSCF could effectively degrade two types of emerging organic contaminants under visible light irradiation Particularly, CSCF could effectively degrade 99.8% of paracetamol (PCT) and 94.0% of bisphenol A (BPA) within 180 min under visible light irradiation ·O2- and h+ played dominant roles during the photocatalytic degradation process. Hydroxylation and cleavage were the main degradation processes. CSCF exhibited good photocatalytic degradation performance in a broad range of ionic strengths, in the presence of common coexisting ions including Cl-, NO3- and SO42-, in a wide range of pH (5-11), and in real water samples including tap water, river water and lake water. Moreover, CSCF could be easily collected after use and exhibited excellent degradation performance in five successive cycles. CSCF has potential applications to treat water with either PCT or BPA contamination. This study provided a new insight into the practical application of COFs. In the experiment, the researchers used many compounds, for example, 2,6-Diaminopyridine(cas: 141-86-6Electric Literature of C5H7N3)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Electric Literature of C5H7N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Ring-Opened Hemiporphyrazines: Helical Molecules Exhibiting Circularly Polarized Luminescence》 was written by Tanaka, Yusuke; Murayama, Tomotaka; Muranaka, Atsuya; Imai, Eiyu; Uchiyama, Masanobu. Reference of 2,6-Diaminopyridine And the article was included in Chemistry – A European Journal in 2020. The article conveys some information:

Authors designed and synthesized a new type of small helical mol. exhibiting intense circularly polarized luminescence (CPL) (12H) by modifying a 20π-electron hemiporphyrazine with a large transition magnetic dipole moment. The hemiporphyrazine ring was opened and one addnl. pyridine unit was introduced, resulting in an overlap of two pyridine rings. X-ray structure anal. confirmed that 12H and its zinc complex (1Zn) adopt a helical geometry. A racemic mixture of 1Zn was resolved into two enantiomers ((P)- and (M)-1Zn), which exhibited CPL with a high luminescence dissymmetry factor (glum) value of ±2.1×10-2. The origin of the large glum value was rationalized by DFT calculations Helical structures could be formed in a diastereoselective manner by covalently attaching chiral units to the skeleton (1’2H and 1’Zn). 1Zn Was found to possess chiral recognition ability for amines. The experimental part of the paper was very detailed, including the reaction process of 2,6-Diaminopyridine(cas: 141-86-6Reference of 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Reference of 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,ACS Applied Materials & Interfaces included an article by Wang, Jing; Zhang, Si; Wu, Pengfei; Shi, Wenxiong; Wang, Zhi; Hu, Yunxia. Product Details of 141-86-6. The article was titled 《In Situ Surface Modification of Thin-Film Composite Polyamide Membrane with Zwitterions for Enhanced Chlorine Resistance and Transport Properties》. The information in the text is summarized as follows:

High-performance chlorine-resistant thin-film composite (TFC) membranes with zwitterions were fabricated by in situ surface modification of polyamide with 2,6-diaminopyridine and the subsequential quaternization with 3-bromopropionic acid. The successful modification of the TFC polyamide surface with zwitterions was confirmed by various characterizations including surface chem., surface hydrophilicity, and surface charge. The transport performance of the membrane was measured in both of the cross-flow reverse osmosis (RO) and forward osmosis processes, and the results showed that the modified TFC membrane improved both of its water permeability and permselectivity with the increased A and A/B ratios upon modification with zwitterions. The chlorination challenging experiments were performed to demonstrate that the modified membrane enhanced its chlorine resistance without affecting its salt rejection upon 16 000 ppm·h chlorination exposure. A chlorination mechanism study illustrated that the modified membrane with zwitterions could prevent the Orton rearrangement of the benzene ring of the polyamide layer. Importantly and excitingly, the optimal chlorinated TFC membrane with zwitterions achieved a very high water flux of 72.15 ± 2.55 LMH with 99.67 ± 0.09% of salt rejection in the cross-flow RO process under 15 bar. In addition to this study using 2,6-Diaminopyridine, there are many other studies that have used 2,6-Diaminopyridine(cas: 141-86-6Product Details of 141-86-6) was used in this study.

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Product Details of 141-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Category: pyridine-derivativesIn 2022 ,《Ruthenium-Catalyzed Dehydrogenative Functionalization of Alcohols to Pyrroles: A Comparison between Metal-Ligand Cooperative and Non-cooperative Approaches》 appeared in Journal of Organic Chemistry. The author of the article were Guin, Amit Kumar; Mondal, Rakesh; Chakraborty, Gargi; Pal, Subhasree; Paul, Nanda D.. The article conveys some information:

Herein, authors report the synthesis and characterization of two ruthenium-based pincer-type catalysts, I (X = Cl, PF6) and II (R = H, Cl), containing two different tridentate pincer ligands, 2-pyrazolyl-(1,10-phenanthroline) and 2-(phenyldiazenyl)-1,10-phenanthroline; 2-((4-chlorophenyl)diazenyl)-1,10-phenanthroline), and their application in the synthesis of substituted pyrroles via dehydrogenative alc. functionalization reactions. In catalyst I (X = Cl, PF6), the tridentate scaffold 2-pyrazolyl-(1,10-phenanthroline) is apparently redox innocent, and all the redox events occur at the metal center, and the coordinated ligands remain as spectators. In contrast, in catalysts II (R = H, Cl), the coordinated azo-aromatic scaffolds are highly redox-active and known to participate actively during the dehydrogenation of alcs. A comparison between the catalytic activities of these two catalysts was made, starting from the simple dehydrogenation of alcs. to further dehydrogenative functionalization of alcs. to various substituted pyrroles to understand the advantages/disadvantages of the metal-ligand cooperative approach. Various substituted pyrroles were prepared via dehydrogenative coupling of secondary alcs. and amino alcs., and the N-substituted pyrroles were synthesized via dehydrogenative coupling of aromatic amines with cis-2-butene-1,4-diol and 2-butyne-1,4-diol, resp. The experimental process involved the reaction of 2,6-Diaminopyridine(cas: 141-86-6Category: pyridine-derivatives)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Engineering Redox Activity in Conjugated Microporous Polytriphenylamine Networks Using Pyridyl Building Blocks toward Efficient Supercapacitors》 were Li, Huixin; Lyu, Wei; Liao, Yaozu. And the article was published in Macromolecular Rapid Communications in 2019. Name: 2,6-Diaminopyridine The author mentioned the following in the article:

Nitrogen-rich conjugated microporous polymers (CMPs) with tunable porosities and reversible redox properties have received increasing interest as electrode materials for supercapacitors. Herein, pyridyl building blocks with different substitutions are selected to synthesize four amine-linked conjugated microporous polytriphenylamine (PTPA) networks via Buchwald-Hartwig cross-coupling reaction engineering the redox activity of PTPAs. The structures, porosities, and redox activities of these four PTPAs are investigated. The electrochem. characterization results show that PTPA obtained using 2,5-diaminopyridine dihydrochloride (i.e., PTPA-25) displays the highest specific capacitances ≤ 335 F g-1 in 1.0 M H2SO4 at a c.d. of 0.5 A g-1. Upon 5000 cycles, PTPA-25 maintains good initial capacitances ≤ 65%, nearly 100% Coulombic efficiencies at a c.d. of 2 A g-1, and high rate properties (remained a high capacitance of 250 F g-1 at 10 A g-1). The effect of different substitutions of pyridyl on the redox activities of the synthesized PTPA electrodes is further proposed, which would give insight into engineering the performance of CMPs-based supercapacitors.2,6-Diaminopyridine(cas: 141-86-6Name: 2,6-Diaminopyridine) was used in this study.

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Name: 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Logic gate behavior and intracellular application of a fluorescent molecular switch for the detection of Fe3+ and cascade sensing of F- in pure aqueous media》 were Dwivedi, Romi; Singh, Divya P.; Singh, Saumya; Singh, Ashish K.; Chauhan, Brijesh S.; Srikrishna, S.; Singh, Vinod P.. And the article was published in Organic & Biomolecular Chemistry in 2019. Electric Literature of C5H7N3 The author mentioned the following in the article:

The nature and coordination sites of the Schiff base 3,3′-(1E,1′E)-(1,3-phenylenebis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-ylidene)dinaphthalen-2-ol (APHN) were tuned by its selective reduction to design a highly efficient fluorescent probe, 3,3′-(pyridine-2,6-diylbis(azanediyl))bis(methylene)dinaphthalen-2-ol (RAPHN). The structures of APHN, RAPHN, and the RAPHN-Fe3+ complex were satisfactorily modeled from the results of d. functional theory (DFT) and time-dependent DFT (TD-DFT) calculations RAPHN worked in pure aqueous medium as a turn on-off-on probe of Fe3+ and F-. The fluorescence nature of the probe in the presence and absence of Fe3+/F- was regulated by a set of mechanisms including -CH=N isomerization and LMCT. A 2 : 1 (M : L) binding stoichiometry was established from a fluorescence Job′s plot and further substantiated from HR-MS studies. The limits of detection of RAPHN for Fe3+ and RAPHN-Fe3+ for F- were found to be 2.49 × 10-7 M and 1.09 × 10-7 M, resp. The RAPHN probe caused no cytotoxicity in gut tissue of Drosophila even at high concentrations The probe displayed excellent bioimaging applications for detection of Fe3+ and F- in gut tissue of Drosophila. A combinatorial logic gate was constructed for the proper understanding of the working principle of RAPHN. In the experiment, the researchers used 2,6-Diaminopyridine(cas: 141-86-6Electric Literature of C5H7N3)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Electric Literature of C5H7N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chu, Chiheng; Yang, Ji; Zhou, Xuechen; Huang, Dahong; Qi, Haifeng; Weon, Seunghyun; Li, Jianfeng; Elimelech, Menachem; Wang, Aiqin; Kim, Jae-Hong published an article in 2021. The article was titled 《Cobalt Single Atoms on Tetrapyridomacrocyclic Support for Efficient Peroxymonosulfate Activation》, and you may find the article in Environmental Science & Technology.Formula: C5H7N3 The information in the text is summarized as follows:

Transition-metal catalysts that can efficiently activate peroxide bonds have been extensively pursued for various applications including environmental remediation, chem. synthesis, and sensing. Here, we present pyridine-coordinated Co single atoms embedded in a polyaromatic macrostructure as a highly efficient peroxide-activation catalyst. The efficient catalytic production of reactive radicals through peroxymonosulfate activation was demonstrated by the rapid removal of model aqueous pollutants of environmental and public health concerns such as bisphenol A, without pH limitation and Co2+ leaching. The turnover frequency of the newly synthesized Co single-atom catalyst bound to tetrapyridomacrocyclic ligands was found to be 2 to 4 orders of magnitude greater than that of benchmark homogeneous (Co2+) and nanoparticulate (Co3O4) catalysts. Exptl. results and d. functional theory simulation suggest that the abundant π-conjugation in the polyaromatic support and strong metal-support electronic interaction allow the catalysts to effectively adsorb and activate the peroxide precursor. We further loaded the catalysts onto a widely used poly(vinylidene fluoride) microfiltration membrane and demonstrated that the model pollutants were oxidatively removed as they simply passed through the filter, suggesting the promise of utilizing this novel catalyst for realistic applications. After reading the article, we found that the author used 2,6-Diaminopyridine(cas: 141-86-6Formula: C5H7N3)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Formula: C5H7N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem