Category: 15420-02-7

A new bitrack sinusoid-like chain templated by Wells-Dawson type polyoxometalate was written by Wang, Xiuli;Hu, Hailiang;Tian, Aixiang;Lin, Hongyan;Li, Jin;Shi, Limin. And the article was included in Inorganic Chemistry Communications in 2010.Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole This article mentions the following:

A new Wells-Dawson type polyoxometalate (POM)-templated compound, [Cu₄(娓?sub>2-O)₂(4,4′-bpo)₄(INA)₂(H₂O)₄][(P₂W₁₈O₆₂)]璺疕₂O (I, 4,4′-bpo = 2,5-bis(4-pyridyl)-1,3,4-oxadiazole; INA = pyridine-4-carboxylic acid), has been hydrothermally synthesized. I contains a novel bitrack sinusoid-like chain constructed from alternating dicopper units and non-linear rigid 4,4′-bpo linkers. Induced by POM templates, the adjacent chains formed elliptical spaces to accommodate the Wells-Dawson type anions. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A new synthesis of symmetrical 2,5-disubstituted 1,3,4-oxadiazoles was written by Bentiss, Fouad;Lagrenee, Michel. And the article was included in Journal of Heterocyclic Chemistry in 1999.Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole This article mentions the following:

Title compounds I [R = (un)substituted phenyl; 2-, 3-, 4-pyridinyl; 2-thienyl] were prepared in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The chemistry of 1,3,4-oxadiazoles with regard to the chemotherapy of tuberculosis was written by Novotny, A.;Brezik, Z.;Pridal, J.;Kalfus, K.. And the article was included in Cesko-Slovenska Farmacie in 1958.Synthetic Route of C12H8N4O This article mentions the following:

2-(4-Pyridyl)-4,5-dihydro-1,3,4-oxadiazol-5-one (I) was prepared by the action of COCl₂ on isonicotinic acid hydrazide (II) at 0-5鎺?according to Lieser and Nischk (C.A. 44, 3979h), U.S. 2,665,279 (C.A. 49, 2521g), and Ger. 923,722 (C.A. 51, 12983c), in 90% yield, m. 275.9-6.1鎺?(hot water). Similarly was prepared from NCCH₂CONHNH₂ (III) and COCl₂ 88% 2-cyanomethyl-4,5-dihydro-1,3,4-oxadiazol-5-one (IV), m. 162.2-2.3鎺?(EtOH). A new procedure is described for the preparation of N¹N²-diacylhydrazines. II (13.7 g.) mixed with 29.1 mL. 80% HCO₂H, allowed to stand 8 h. at laboratory temperature, evaporated in vacuo, and the residue crystallized from 235 mL. AcOBu yielded 83% N¹-formyl-N²isonicotinoylhydrazine, m. 141.2-1.7鎺? Similarly were prepared: N¹-formyl-N²-cyanohydrazine, m. 153.2-3.8鎺?(EtOH); N¹-acetyl-N²-isonicotinoylhydrazine (V) from II, water, and AcOAc, m. 162.2-2.5鎺?(AcOBu); N¹propionyl-N²-isonicotinoylhydrazine, m. 130.2-0.4鎺?(AcOBu); N¹-butyryl-N²-isonicotinoyl-hydrazine, m. 140.1-0.3鎺?(2:1 AcOBu-C₅H₅N). 2-Alkyl-5-(4-pyridyl)-1,3,4-oxadiazoles were prepared by the modified method of McMillan, et al. (C.A. 48, 11413h). V (5.37 g.) and 5 g. P₂O₅ heated with stirring to 100-30鎺? the resulting product dissolved after cooling in 100 mL. water and pH simultaneously made to 8-9 with Na₂CO₃, the solution evaporated, dried, the residue extracted 4 h. with C₅H₅N in a Soxhlet apparatus, the excess solution evaporated, and crystallized 15 h. at 4鎺?yielded 26% 2-methyl-5-(4-pyridyl)-1,3,4-oxadiazole, m. 150.5-1.0鎺?(boiling EtOH). Similarly was prepared 29% 2-Et derivative m. 58.0-8.5鎺?(EtOH), while the synthesis of the 2-Pr derivative and 2-(4-pyridyl)-1,3,4-oxadiazole was not successful. Dehydration was also achieved by heating with high boiling ethers (Ph₂O) to 250-70鎺?and by azeotropic dehydration (25-30% yields). Bacteriol. tests showed a high tuberculostatic effect in vivo of I (similar to II) and IV (similar to III), while 2-alkyl-5-(4-pyridyl)-1,3,4-oxadiazoles showed in vitro only a low activity. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Synthetic Route of C12H8N4O).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Synthetic Route of C12H8N4O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chemical constitution and activity of bipyridinium herbicides. Part XIV. Reduction potential and herbicidal activity of 4,4′-(1,3,4-thiadiazole-2,5-diyl)- and 4,4′-(1,3,4-oxadiazole-2,5-diyl)bis(1-methylpyridinium) diiodides was written by Kennedy, Debra A.;Summers, Lindsay A.. And the article was included in Journal of Heterocyclic Chemistry in 1981.Related Products of 15420-02-7 This article mentions the following:

The diquaternary salts 4,4′-(1,3,4-thiadiazole-2,5-diyl)bis(1-methylpyridinium) diiodide [23622-28-8] and 4,4′-(1,3,4-oxadiazole-2,5-diyl)bis(1-methylpyridinium) diiodide [78003-53-9] are reduced in aqueous solution in the pH range 5.4-8.0 to radical cations at a potential of -0.39 V and -0.48 V, resp. Herbicidal activity was demonstrated in postemergence tests at 8-16 kg/ha against a variety of grass flora, but herbicidal activity was 1/30 and 1/60, resp., less than that of paraquat. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Related Products of 15420-02-7).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Related Products of 15420-02-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridinium and imidazolium 1,3,4-oxadiazole ionic liquid crystals: a thermal and photophysical systematic investigation was written by Westphal, Eduard;Henrique da Silva, Danilo;Molin, Fernando;Gallardo, Hugo. And the article was included in RSC Advances in 2013.Product Details of 15420-02-7 This article mentions the following:

The authors present the synthesis and complete structural characterization of twenty five 1,3,4-oxadiazole mols. (ionic and nonionic) with some systematic structural variations, such as number of counterions, number of alkoxy chains, alkyl chain size, type of counterion and its position on the mol. The thermal and photophys. properties for all compounds were studied allowing a complete and interesting simultaneous study of the effect of structural changes on these properties. Every parameter studied affected both the thermal and photophys. properties. For these bent core mols., the liquid crystalline behavior was observed only for compounds containing one counterion, SmA (monolayer or bilayer) being the predominant phase. The neutral (nonionic) compounds and the imidazolium derivatives showed emission at 閳?60 nm and a high quantum yield, while most of the pyridinium derivatives showed emission at 閳?30 nm, a low quantum yield and a complex photophys. behavior. In all cases, the quantum yield for the different counterions follows the sequence ClO₄^– > BF₄^– > DS^– > NO₃^– > Br^–(I^–). In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Product Details of 15420-02-7).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Product Details of 15420-02-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis and characterization of new coordination polymers generated from oxadiazole-containing ligands and IIB metal ions was written by Cheng, Jun-Yan;Dong, Yu-Bin;Huang, Ru-Qi;Smith, Mark D.. And the article was included in Inorganica Chimica Acta in 2005.Recommanded Product: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole This article mentions the following:

The coordination chem. of the oxadiazole-containing rigid bidentate ligands 2,5-bis(4-pyridyl)-1,3,4-oxadiazole (L1) and 2,5-bis(3-pyridyl)-1,3,4-oxadiazole (L2) with inorganic IIB metal salts were studied. Five new coordination polymers (1–5) were prepared by solution reactions and fully characterized by IR spectroscopy, elemental anal., and single-crystal x-ray diffraction. Cd(L1)₂(MeCN)₂(ClO₄)₂璺?MeCN)₂ (1) crystallized in the monoclinic space group P2₁/c, a 8.4028(5), b 21.3726(13), c 10.5617(7) 鑴? 灏?95.1200(10)鎺? and Z = 2. In the solid state, it adopts an infinite two-dimensional polymeric structural motif with effective cross section of 閳?4.31 鑴?14.31 鑴? Cd(L2)(H₂O)(NO₃)₂ (2) crystallized in the monoclinic Ia, a 7.1203(5), b 22.2475(15), c 20.2652(16) 鑴? 灏?90.6080(10)鎺? and Z = 8. In the solid state, the two Cd(II) centers are connected to each other by L2 ligands and bridging nitrates into a two-dimensional network. [ZnCl₂(L1)] (3) and [HgI₂(L1)]璺疢eCN (4) crystallized in the monoclinic crystal system (3: space group P2₁/c, a 5.3702(3), b 20.4800(11), c 12.4093(7) 鑴? 灏?94.7930(10)鎺? and Z = 4; 4: space group P2/n, a 17.2733(11), b 5.2173(3), c 20.4069(13) 鑴? 灏?102.8690(10)鎺? and Z = 4). In the solid state, Zn(II) and Hg(II) metal centers are connected to each other by L1 ligands into a zigzag chain motif. Compound 5 (HgBr₂(L2) is different from 3 and 4, monoclinic, P2(1)/n, a 5.470(4), b 16.271(13), c 16.486(12) 鑴? 灏?93.197(15)鎺? and Z = 4) and adopts a novel 1-dimensional helical chain motif which resulted from the relative different coordinated orientation of the two N-donors on L2 ligand. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Recommanded Product: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Recommanded Product: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Three POM-based coordination polymers: hydrothermal synthesis, characterization, and catalytic activity in epoxidation of styrene was written by Ren, Yuanhang;Du, Chengbo;Feng, Sujiao;Wang, Chunling;Kong, Zuping;Yue, Bin;He, Heyong. And the article was included in CrystEngComm in 2011.Formula: C12H8N4O This article mentions the following:

Three polyoxometalates (POM)-based coordination polymers, [Cu^II₂(C₅H₅NCOO)₂(4-bpo)₂(H₂O)₂]SiW₁₂O₄₀·H₂O (1), [Cu^I₄(4-bpo)₆]SiW₁₂O₄₀·3H₂O (2), and [Cu^I₄(3-bpo)₄]SiW₁₂O₄₀·3H₂O (3), were hydrothermally synthesized from the mixture of H₄SiW₁₂O₄₀, copper salts, and 3-bpo (2,5-bis(3-pyridyl)-1,3,4-oxadiazole) or 4-bpo (2,5-bis(4-pyridyl)-1,3,4-oxadiazole) and characterized by elemental anal., IR spectroscopy, TGA, and single crystal x-ray diffraction. The 4-bpo mols. are connected into an infinite double-chain in compound 1 as a bidentate ligand. Compound 2 contains large hexagonal prism shaped mol. cages defined by copper ions and 4-bpo mols. which wrap Keggin ions inside. In compound 3 {Cu₂(3-bpo)₂} mol. rings connect with Keggin ions to form a 1D chain. By inspection of the structures, the geometry and the coordination mode of bpo ligands play important roles in the formation of 1-3. The catalytic performance of 1-3 was studied for epoxidation of styrene using tert-Bu hydroperoxide (TBHP) as the oxidant. Compounds 1–3 present promising activity as heterogeneous catalysts while compound 1 exhibits the best yield of styrene epoxide. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Formula: C12H8N4O).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Formula: C12H8N4O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A new 2D Hg^II coordination polymer containing novel coordination mode of 2,5-bis(4-pyridyl)-1,3,4-oxadiazole (bpo) ligand, [Hg(μ-bpo)₂(N₃)₂]_n: Spectroscopic, thermal, fluorescence and structural studies was written by Atoub, Najmeh;Mahmoudi, Ghodrat;Morsali, Ali. And the article was included in Inorganic Chemistry Communications in 2007.Reference of 15420-02-7 This article mentions the following:

A new two-dimensional Hg^II coordination polymer containing 2,5-bis(4-pyridyl)-1,3,4-oxadiazole (bpo) and azide anions, [Hg(μ-bpo)₂(N₃)₂]_n, was synthesized and characterized by elemental anal., IR-, ¹H NMR-, ¹³C NMR spectroscopy and structurally determined by x-ray single-crystal diffraction. The thermal stability of [Hg(μ-bpo)₂(N₃)₂]_n was studied by thermal gravimetric (TG) and differential thermal analyses (DTA). The single-crystal x-ray data shows that ligand bpo is bridged via one pyridyl N and one oxadiazole N atom, as a novel coordination mode of the ligand bpo. Also, the ligand and complex are luminescent in the solid state, with emission maxima in the visible light region (λ_max = 470 nm for both bpo and [Hg(μ-bpo)₂(N₃)₂]_n). In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Reference of 15420-02-7).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Reference of 15420-02-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Entangled metal-organic frameworks modulated by N-donor ligands of different conformations was written by Guo, Hua-Dong;Qiu, Dong-Fang;Guo, Xian-Min;Zheng, Guo-Li;Wang, Xiao;Dang, Song;Zhang, Hong-Jie. And the article was included in CrystEngComm in 2009.HPLC of Formula: 15420-02-7 This article mentions the following:

Based on the aromatic dicarboxylic acid and N-donor ligands with different conformations, four Zn(II) metal-organic frameworks, namely [Zn(mfda)(L¹)] (1), [Zn₂(mfda)₂(L₂)]·DMF·H₂O (2), [Zn₂(mfda)2(L³)(H₂O)]·DMF (3) and [Zn₂(mfda)₂(L⁴)] (4) were synthesized (mfda = 9,9-dimethylfluorene-2,7-dicarboxylate anion, L¹ = 1,10-phenanthroline, L² = 4,4′-bipyridine, L³ = 2,5-bis(4-pyridyl)-1,3,4-oxadiazole and L⁴ = 1,4-bis(imidazol-1-ylmethyl)benzene). Single-crystal x-ray diffraction revealed that all compounds exhibit entangled structures. Compound 1 is composed of 1D zigzag chains that are entangled through the π-π stacking interactions to generate a three-fold interpenetrating diamond-like networks. 2 Exhibits a two-fold interpenetrating (αPo) net, which leaves 1D channels with high free volume In 3, parallel mutual polythreadings of 2D layers are connected by hydrogen bonds into a self-penetrating framework with (4⁴·6¹⁰·7)(4·5·6)(4⁶·5²·6¹⁶·7³·9) topol. For 4, the interpenetrating 2D layers are connected into a self-interpenetrating net with (4⁹·6⁶) topol. The potential of N-donor ligands to produce interesting metal-organic frameworks was studied. Luminescent studies show that 1–4 exhibit strong blue fluorescent emissions. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7HPLC of Formula: 15420-02-7).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.HPLC of Formula: 15420-02-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Self-assembled half-sandwich Ir, Rh-based organometallic molecular boxes for reversible trapping of halocarbon molecules was written by Han, Ying-Feng;Fei, Yue;Jin, Guo-Xin. And the article was included in Dalton Transactions in 2010.Category: pyridine-derivatives This article mentions the following:

Reactions of [Cp^*MCl(μ-Cl)]₂ (M = Ir or Rh) with 6,11-dihydroxy-5,12-naphthacenedione (H₂DHNA) in the presence of a base, gave the corresponding binuclear complexes [Cp^*₂M₂(μ-DHNA)Cl₂] (M = Ir (1a); M = Rh (1b)), resp. Treatment of 1a or 1b with bidentate ligands (L) such as pyrazine, 4,4′-dipyridine (bpy), E-1,2-bis(4-pyridyl)ethene (bpe) or 2,5-bis(4-pyridyl)-1,3,5-oxadiazole (bpo) in the presence of AgOTf (OTf = CF₃SO₃) in MeOH, gave the corresponding tetranuclear complexes, [Cp^*₄M₄(μ-DHNA)₂(μ-L)₂](OTf)₄ (M = Ir, L = pyrazine (3a), bpy (4a), bpe (5a), bpo (6a); M = Rh , L = pyrazine (3b), bpy (4b), bpe (5b), bpo (6b)), resp. X-ray analyses of 3a, 3b, 4a, 4b, 5a and 5b revealed that each of the half-sandwich metal centers was connected by DHNA and bidentate bridging ligands to construct a rectangular cavity with different dimensions, and strong π-π interactions between independent mols. to form rectangular channels in the solid-state. Complexes 3a and 3b based on H₂DHNA and pyrazine spacing ligands exhibit selective and reversible small organic mols. adsorption properties. Intercalated supramol. arrays were obtained by introducing Cl₂C:CCl₂ templates into the middle of the 1-dimensional lines of 3b. The 2-dimensional framework was stabilized due to weak C-H···Cl interactions and the displaced face-to-face π···π interactions between the planes of the monomeric complexes. The hollow cavities in the 2-dimensional frameworks still exhibit selective and reversible CH₂Cl₂ adsorption properties. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Category: pyridine-derivatives).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem