Category: 16133-25-8

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Computed Properties of 16133-25-8.

Sun, Bin;Ding, Hao;Tian, Hai-Xia;Huang, Pan-Yi;Jin, Can;Wu, Chun-Lei;Shen, Run-Pu research published 《 Photo-Triggered Self-Induced Homolytic Dechlorinative Sulfonylation/Cyclization of Unactivated Alkenes: Synthesis of Quinazolinones Containing a Sulfonyl Group》, the research content is summarized as follows. A self-photocatalyzed sulfonylation/cyclization of quinazolinones containing unactivated alkenes with various sulfonyl chlorides was developed. The protocol provided access to sulfonyl radicals via energy transfer from quinazolinone skeleton to sulfonyl chloride. Notably, transformations proceeded without any external photocatalysts, additives, or oxidants, providing an alternative method for fabricating sulfonylated compounds I [R = Et, cyclopropyl, Ph, etc.; R¹ = H, 3-F, 2-MeO, etc.; n = 0, 1].

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Computed Properties of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Reference of 16133-25-8.

Sun, Bin;Tian, Hai-Xia;Ni, Zhi-Gang;Huang, Pan-Yi;Ding, Hao;Li, Bing-Qian;Jin, Can;Wu, Chun-Lei;Shen, Run-Pu research published 《 Photocatalyst-, metal- and additive-free regioselective radical cascade sulfonylation/cyclization of benzimidazole derivatives with sulfonyl chlorides induced by visible light》, the research content is summarized as follows. Herein, an environmentally friendly and practical protocol for the visible-light-triggered regioselective radical cascade sulfonylation/cyclization of unactivated alkenes towards the synthesis of polycyclic benzimidazoles containing the sulfone group has been developed. Notably, the control experiments demonstrated that a radical pathway was involved in this reaction, and a sulfonyl radical center was initially generated via self-homolysis of sulfonyl chloride upon irradiation Moreover, this protocol features a wide substrate scope, high atom economy, and excellent regioselectivity, and is easy to scale up.

Reference of 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. COA of Formula: C5H4ClNO2S.

Sun, Yucong;Feng, Cancan;Wang, Peisong;Yang, Fan;Wu, Yangjie research published 《 Cobalt-catalyzed C8-H sulfonylation of 1-naphthylamine derivatives with sodium sulfinates》, the research content is summarized as follows. A facile and efficient protocol for cobalt-catalyzed regioselective C₈-H sulfonylation of 1-naphthylamine derivatives with sodium sulfinates, affording sulfonylated naphthylamines in moderate to good yields was described. The reaction exhibited broad functional group tolerance and high regioselectivity. Note that the addition of a catalytic amount of NFSI or Selectfluor as the auxiliary ligand would enhance the reaction efficiency. Furthermore, the picolinamide moiety as a bidentate directing group likely played a key role in this regioselective transformation.

COA of Formula: C5H4ClNO2S, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. COA of Formula: C5H4ClNO2S.

Tabti, Redouane;Lamoureux, Francois;Charrier, Celine;Ory, Benjamin;Heymann, Dominique;Bentouhami, Embarek;Desaubry, Laurent research published 《 Development of prohibitin ligands against osteoporosis》, the research content is summarized as follows. Current therapeutic approaches to osteoporosis display some potential adverse effects and a limited efficacy on non-vertebral fracture reduction Some sulfonylamidines targeting the scaffold proteins prohibitins-1 and 2 (PHB1/2) have been showed to inhibit the formation of osteoclasts in charge of bone resorption. Herein, we report the development of a second generation of anti-osteoclastic PHB ligands. The most potent compound, IN45, showed 88% inhibition at the low concentration of 5μM, indicates that it might serve as a basis for the development of new antiosteoporotic drugs.

COA of Formula: C5H4ClNO2S, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Recommanded Product: Pyridine-3-sulfonyl chloride.

Takemura, Hinano;Orimoto, Gaku;Kobayashi, Akihiro;Hosoya, Takamitsu;Yoshida, Suguru research published 《 Modular synthesis of triazoles from 2-azidoacrylamides having a nucleophilic amino group》, the research content is summarized as follows. Assembling methods using 2-azidoacrylamides having a nucleophilic amino group were disclosed. Divergent transformations of the amine-type trivalent platform were accomplished with a wide variety of electrophiles to obtain a broad range of 2-azidoacrylamides involving a fluorosulfonyl group-containing trivalent platform. Consecutive click conjugations including triazole formation, thiol-ene-type 1,4-addition, and SuFEx reactions realized the efficient assembly of easily available simple modules.

Recommanded Product: Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Electric Literature of 16133-25-8.

Song, Fan;Yang, Chao;Shao, Xiaotao;Du, Lei;Zhu, Jing;Kan, Chun research published 《 A reversible “turn-off-on” fluorescent probe for real-time visualization of mercury(II) in environmental samples and its biological applications》, the research content is summarized as follows. In this study, we synthesized a novel fluorescent probe (S-TC) based on Thiooxo-Rhodamine B. In the design of the probe, we sulfided carbonyl groups of rhodamine spironolactam to thiocarbonyl groups. C=S functional group was used as a recognition group for Hg²⁺. S-TC has a good spectral response to Hg²⁺ in the EtOH/H₂O solution (1:1, volume/volume) with low detection limits and high binding constants The detection limit and the association constant was calculated as 0.077 μM and 1.70 × 10⁴ M^-1, resp. S-TC displayed the traditional reversible “turn-off-on” fluorescence change with 1:1 binding stoichiometry. It is feasible to detect Hg²⁺ in real environmental water by S-TC. Biol. experiments demonstrated that S-TC can be used to detect to Hg²⁺ in living cells, animals and plant tissues.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Electric Literature of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Reference of 16133-25-8.

Song, Fan;Shao, Xiaotao;Zhu, Jing;Bao, Xiaofeng;Du, Lei;Kan, Chun research published 《 Reversible “turn-off-on” fluorescence response of Fe(III) towards Rhodamine B based probe in vivo and plant tissues》, the research content is summarized as follows. A Fe³⁺-specific probe (N-TC)(I) based on Rhodamine B was designed and synthesized. N-TC has a good spectral response to Fe³⁺ in the EtOH/H₂O solution (1:1, volume/volume, HEPES, 0.5 mM, pH = 7.38) with low detection limits and high binding constants N-TC displays the reversible “turn-off-on” fluorescence response with 1:1 binding stoichiometry. It is further proven to be practical in sensitively monitoring trace Fe³⁺ in environmental water specimens. Biol. experiments demonstrated that N-TC can be resp. used as a probe for detection of Fe³⁺ in living cells, animals and plant tissues.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Reference of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Name: Pyridine-3-sulfonyl chloride.

Song, Mengmeng;Zhang, Zhiguo;Zheng, Dan;Li, Xiang;Liang, Rui;Zhao, Xu-na;Shi, Lei;Zhang, Guisheng research published 《 Hypervalent organoiodine promoted dearylation reaction of N-aryl sulfonamides》, the research content is summarized as follows. An efficient Dess-Martin periodinane (DMP)-promoted dearylation of N-arylsulfonamides RS(O)₂NHR¹ (R = Ph, 2-naphthyl, 2-thienyl, etc.; R¹ = quinolin-8-yl, 2-methylphenyl, 4-methylbenzyl, etc.) was developed through a highly selective oxidative cleavage of the inert C (aryl)-N bonds in secondary sulfonamides while leaving the S-N bond unchanged. This metal-free reaction proceeds under mild conditions and provides access to various biol. important primary sulfonamides, some of which are otherwise unattainable using conventional aminolysis and hydrolysis methods. The concise and efficient dearylation reaction provides the use of an aryl group as a removable protecting sulfonamide group under metal catalyst-free conditions.

Name: Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Formula: C5H4ClNO2S.

Song, Qinghao;Zhao, He;Sun, Yanping;Jiang, Huanfeng;Zhang, Min research published 《 Direct C(sp³)-H Sulfonylation of Xanthene Derivatives with Sodium Sulfinates by Oxidative Copper Catalysis》, the research content is summarized as follows. By employing a readily available CuCl/DDQ catalyst system, herein a direct C(sp³)-H sulfonylation of xanthene derivates I (R = H, Me; R¹ = H, Me, Cl, Et, etc.;RR¹ = -CH=CH-CH=CH-; R² = H, Me, Br, CF₃, Ph; R³ = H, Me, Et, Cl; Z = O, S, NCH₃, NBn, etc.) with odorless sodium sulfinates R⁴S(O)₂Na (R⁴ = Me, Ph, 4-chlorophenyl, thiophen-2-yl, etc.) was reported. Various 9H-xanthenes I (Z = O), thioxanthenes I (Z = S), and 9,10-dihydroacridines I (Z = NCH₃, NPh, NBn, NCbz) are efficiently transformed into the desired benzylic sulfonyl products II via a radical/radical cross-coupling process, proceeding with the merits of broad substrate scope, operational simplicity, good functional group compatibility, and mild reaction conditions.

Formula: C5H4ClNO2S, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Reference of 16133-25-8.

Song, Xinning;Jiang, Zhiyang;Li, Jianing;Lu, Xingxing;Han, Qing;Zhu, Kai;Li, Huilin;Ling, Yun;Duan, Hongxia research published 《 Synthesis, antifungal activity, and molecular dynamics study of novel geranyl aromatic sulfonamide compounds as potential complex III inhibitors》, the research content is summarized as follows. Essential oils (EOs), as unique natural products, are promising resources for the discovery of green agrochems. The main ingredient geraniol of citronella oil was found to exhibit substantial antifungal activities in this study. Therefore, a series of novel geranyl aromatic sulfonamide compounds were synthesized and found to display considerable antifungal activities. Two geranyl thiofuran-sulfonamide compounds 4c-1 (median effective concentration (EC50) against Rhizoctonia solani: 24.97 mg/L and EC50 against Sclerotinia sclerotiorum: 27.26 mg/L), 4c-2 (EC50 against S. sclerotiorum: 18.53 mg/L) and one geranyl pyridine-sulfonamide compound 4d-2 (EC50 against R. solani: 29.31 mg/L and EC50 against S. sclerotiorum: 29.98 mg/L) were screened as “star mols.” due to their excellent antifungal activities. The preliminary structure-activity relationship (SAR) study revealed that the introduction of various aromatic heterocycles maybe an efficient protocol to improve the fungicidal activities of geranyl aromatic sulfonamide compounds The mol. mechanisms of the geranyl aromatic sulfonamide compounds were clarified by performing mol. docking and mol. dynamics (MD) simulations. Three “star mols.” of these geranyl aromatic sulfonamide compounds were found to bind to Complex III through several hydrogen bonds and π-interactions with crucial residues TRP17, GLY20 etc. Their binding free energies were calculated to be strong ranging from -50.60 to -39.44 kcal/mol by MM/GBSA method, which suggested the geranyl aromatic sulfonamide compounds were potential Complex III inhibitors. The main component originating from the natural plant EOs ought to be studied in the future to discover novel pathogenic fungicidal candidates.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Reference of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem