Category: 16133-25-8

In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. For this reason, pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Application of C5H4ClNO2S.

Obradors, Carla;List, Benjamin research published 《 Azine Activation via Silylium Catalysis》, the research content is summarized as follows. A direct, catalytic and selective functionalization of azines via silylium activation was described. The catalyst design enabled mild conditions and a remarkable functional group tolerance in a one-pot setup.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Application of C5H4ClNO2S

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. Recommanded Product: Pyridine-3-sulfonyl chloride.

Meng, Xiao-Xiao;Kang, Qing-Qing;Zhang, Jun-Yao;Li, Qiang;Wei, Wen-Ting;He, Wei-Min research published 《 Visible-light-initiated regioselective sulfonylation/cyclization of 1,6-enynes under photocatalyst- and additive-free conditions》, the research content is summarized as follows. Without employing any photocatalyst and additive, an economical, eco-friendly and practical strategy was developed for the visible-light-initiated regioselective sulfonylation/cyclization of 1,6-enynes in a biomass-derived green solvent 2-methylTHF from easily accessible sulfonyl chlorides under open-air conditions at room temperature Compared with conventional heating conditions, the use of a 3 W blue light-emitting diode (LED) or sunlight not only reduces energy consumption but also minimizes side reactions. This transformation showed excellent regioselectivity, mild reaction conditions, broad substrate scope and ease of scale-up. Moreover, mechanistic studies indicated that a sulfonyl radical pathway was involved in this reaction.

Recommanded Product: Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Formula: C5H4ClNO2S.

Modak, Atanu;Pinter, Emily N.;Cook, Silas P. research published 《 Copper-Catalyzed, N-Directed Csp³-H Trifluoromethylthiolation (-SCF₃) and Trifluoromethylselenation (-SeCF₃)》, the research content is summarized as follows. A direct and versatile copper-catalyzed trifluoromethylthiolation and trifluoromethylselenation of primary, secondary, and tertiary aliphatic C-H bonds was developed. The reaction provides direct access to mols. containing these emerging moieties in the presence of a wide range of common functional groups and in complex mol. environments.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Formula: C5H4ClNO2S

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Application In Synthesis of 16133-25-8.

Liu, Yishuai;Zhu, Haibo;Yang, Liu;Xie, Zongbo;Jiang, Guofang;Le, Zhang-Gao;Tu, Tao research published 《 Transition-Metal-Free Approaches to Arylsulfones using Benzylic Ammonium Salts through C-N Bond Cleavage》, the research content is summarized as follows. A transition-metal-free approach to benzyl sulfones I (R¹ = 2-Me, 4-Me, 4-MeO, etc.; R² = H, 3-Me, 4-tBu, etc.) by using sodium sulfinates and benzyl ammonium salts is described. The protocol provides a simple and direct method to realize the C-N bond cleavage in the presence of readily available Cs₂CO₃. During the reaction process, a range of functional groups with respect to both sodium sulfinates and benzylic ammonium salts were well compatible, leading to various benzyl sulfones in moderate to good yields.

Application In Synthesis of 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Synthetic Route of 16133-25-8.

Liu, Zhi-Lin;Ye, Zhi-Peng;Chen, Yi-Xuan;Zheng, Yu;Xie, Zhen-Zhen;Guan, Jian-Ping;Xiao, Jun-An;Chen, Kai;Xiang, Hao-Yue;Yang, Hua research published 《 Visible-Light-Induced, Palladium-Catalyzed 1,4-Difunctionalization of 1,3-Dienes with Bromodifluoroacetamides》, the research content is summarized as follows. A highly modular 1,4-difunctionalization of 1,3-dienes with bromodifluoroacetamides and sulfinates/amines through a photoinduced palladium-catalyzed radical relay process is described herein. This developed protocol offers a facile and general route to access a variety of value-added CF₂-incorporated alkenes in moderate to good yields. The versatility and flexibility of this approach have been well illustrated by readily accessible starting materials, synthetic convenience, and wide functional group compatibility.

Synthetic Route of 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Category: pyridine-derivatives.

Luo, Lihua;Tang, Juan;Sun, Rui;Li, Wenjing;Zheng, Xueli;Yuan, Maoling;Li, Ruixiang;Chen, Hua;Fu, Haiyan research published 《 Direct C-H Sulfonylimination of Pyridinium Salts》, the research content is summarized as follows. A direct pyridinium C-H sulfonylimination has been developed for the synthesis of sulfonyl iminopyridine derivatives I (R = H, CN, Ph, thiophen-2-yl, etc.; R¹ = H, OMe, Ph, thiophen-3-yl, etc.; R² = H, cyclopropyl, Ph, 4-bromophenyl, etc.; R¹R² = -CH=CH-CH=CH-; R³ = Me, Et, i-Pr, etc.; R⁴ = Et, Ph, pyridin-3-yl, etc.) with high efficiency. This transformation features the direct and efficient formation of a C=N bond with a high functional group tolerance under metal-free conditions. The spectroscopic properties potentially enable these sulfonyl iminopyridine compounds I to be useful new emitting materials.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Safety of Pyridine-3-sulfonyl chloride.

Luo, Xu;Wang, Shengchun;Lei, Aiwen research published 《 Electrochemical-Induced Hydroxysulfonylation of α-CF₃ Alkenes to Access Tertiary β-Hydroxysulfones》, the research content is summarized as follows. An electrochem. hydroxysulfonylation of α-CF₃ alkenes RC(=CH₂)CF₃ (R = 4-CH₃OC₆H₄, 2,3-dihydro-1,4-benzodioxin-6-yl, naphthalen-2-yl, etc.) was accomplished in this work. By using easily available sodium sulfinates R¹SO₂Na (R¹ = Me, Ph, cyclopropyl, etc.) as the sulfonylating agents, a series of valuable α-trifluoromethyl tertiary alcs. RC(OH)CF₃CH₂S(O)₂R¹ was synthesized under mild and environmentally friendly electrolysis conditions in moderate to good yields. The preliminary mechanistic investigation indicates that this difunctional reaction involves a radical process via a sulfonyl radical. Gram-scale synthesis shows the significant potential application of this protocol.

Safety of Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Recommanded Product: Pyridine-3-sulfonyl chloride.

Lv, Yunhe;Han, Wanru;Pu, Weiya;Xie, Jinhui;Wang, Axue;Zhang, Mengyue;Wang, Jin;Lai, Junrong research published 《 Copper-catalyzed regioselective 1,4-sulfonylcyanation of 1,3-enynes with sulfonyl chlorides and TMSCN》, the research content is summarized as follows. A novel and practical copper-catalyzed reaction for the 1,4-sulfonylcyanation of 1,3-enynes under mild conditions was described. This protocol provided efficient and straightforward access to a variety of 5-sulfonylpenta-2,3-dienenitrile derivatives with excellent functional group tolerance and good regioselectivity from readily available 1,3-enynes and com. available sulfonyl chlorides and TMSCN. A mechanism involving sulfonyl and allenyl radical species was proposed.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Recommanded Product: Pyridine-3-sulfonyl chloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Related Products of 16133-25-8.

Lin, Biyue;Kou, Jingping;Xiao, Qingbo;Wu, Shuming;Hu, Ji’an;Li, Jianbing;Zhu, Zhu;Zhou, Xinglin;Xin, Libo;Li, Yanhua;Wang, Zhongqing research published 《 Identification, characterization, synthesis of major metabolites biotransformed from vonoprazan fumarate》, the research content is summarized as follows. A first synthetic research concerning four observed metabolites and their deuterium-labeled analogs of reflux esophagitis drug vonoprazan fumarate was reported. Among which the synthetic methods of three metabolites M – I, M-III, M-IV-Sul, and four stable isotop labeled analogs M-I-d₄, M-II-d₄, M-III-d₄, M-IV-Sul-d₄ was not yet been reported before. The structures of these compounds were elucidated on the basis of MS and NMR spectroscopy.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Related Products of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Computed Properties of 16133-25-8.

Lin, Xionghao;Sajith, Ayyiliath M.;Wang, Songping;Kumari, Namita;Choy, Meng S.;Ahmad, Asrar;Cadet, Dana R.;Gu, Xinbin;Ivanov, Andrey I.;Peti, Wolfgang;Kulkarni, Amol;Nekhai, Sergei research published 《 Structural Optimization of 2,3-Dihydro-1H-cyclopenta[b]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition》, the research content is summarized as follows. Combination antiretroviral therapy (cART) suppresses human immunodeficiency virus-1 (HIV-1) replication but is unable to permanently eradicate HIV-1. Importantly, cART does not target HIV-1 transcription, which is reactivated in latently infected reservoirs, leading to HIV-1 pathogenesis including non-infectious lung, cardiovascular, kidney, and neurodegenerative diseases. To address the limitations of cART and to prevent HIV-1-related pathogenesis, we developed small mols. to target the noncatalytic RVxF-accommodating site of protein phosphatase-1 (PP1) to prevent HIV-1 transcription activation. The PP1 RVxF-accommodating site is critical for the recruitment of regulatory and substrate proteins to PP1. Here, we confirm that our previously developed 1E7-03 compound binds to the PP1 RVxF-accommodating site. Iterative chem. alterations to 1E7-03 furnished a new analog, HU-1a, with enhanced HIV-1 inhibitory activity and improved metabolic stability compared to 1E7-03. In a Split NanoBit competition assay, HU-1a primarily bound to the PP1 RVxF-accommodating site. In conclusion, our study identified HU-1a as a promising HIV-1 transcription inhibitor and showed that the PP1 RVxF-accommodating site is a potential drug target for the development of novel HIV-1 transcription inhibitors.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Computed Properties of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem