16179-97-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 16179-97-8, name is 2-(Pyridin-2-yl)acetic acid hydrochloride. This compound has unique chemical properties. The synthetic route is as follows.
[0187] To the solution of compound of Example 38 (40 mg, 0.05 mmol), catalytic amount of dimethylaminopyridine and 2-pyridylacetic acid hydrochloride (18 mg, 0.10 mmol) in CH2Cl2 (2 mL) was added 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride (50 mg, 0.26 mmol). The reaction was stirred at room temperature for 16 h before being diluted with ethyl acetate (50 mL). The organic solution was washed with sat. aq. NH4Cl (5 mL), sat. aq. NaHCO3 (5 mL) and brine (5 mL), dried over MgSO4, and concentrated. The crude product was dissolved in methanol (5 mL) and stirred at room temperature for 72 h. Concentration and purification by chromatography (silica gel, 95:5:0.3 dichloromethane/methanol/conc. NH4OH) yielded 30 mg (68%) of the title compound. MS 906 (M+H)+.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 16179-97-8, 2-(Pyridin-2-yl)acetic acid hydrochloride.
Reference:
Patent; Henninger, Todd C.; Macielag, Mark J.; Marinelli, Brett A.; Zhu, Bin; US2004/18994; (2004); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem