Category: 169205-95-2

A new synthetic route of 2-(Methylthio)oxazolo[4,5-b]pyridine

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 169205-95-2, 2-(Methylthio)oxazolo[4,5-b]pyridine.

Electric Literature of 169205-95-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 169205-95-2, name is 2-(Methylthio)oxazolo[4,5-b]pyridine, molecular formula is C7H6N2OS, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Step 3: Preparation of 2-morpholinooxazolo[4,5-b]pyridine To a solution of 2-(methylthio)oxazolo[4,5-b]pyridine (2.0g, 12.12 mmol) in THF (5mL) was added morpholine (5mL) and heated at 75 C overnight. The solvent was distilled off to afford the title compound (2.0g, 83.3%). 1HNMR (DMSO-d6, 300MHz): delta 8.20-8.10 (d, 1H), 7.80-7.70 (d, 1H), 7.15-7.00 (m, 1H), 3.75- 3.72 (m, 4H), 3.63-3.52 (m, 4H). LCMS: m/z: 206.5 (M+l) +.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 169205-95-2, 2-(Methylthio)oxazolo[4,5-b]pyridine.

Reference:
Patent; AURIGENE DISCOVERY TECHNOLOGIES LIMITED; GUMMADI, Venkateshwar, Rao; SAMAJDAR, Susanta; WO2015/104688; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The origin of a common compound about 2-(Methylthio)oxazolo[4,5-b]pyridine

The chemical industry reduces the impact on the environment during synthesis 169205-95-2, I believe this compound will play a more active role in future production and life.

Synthetic Route of 169205-95-2, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.169205-95-2, name is 2-(Methylthio)oxazolo[4,5-b]pyridine, molecular formula is C7H6N2OS, molecular weight is 166.2, as common compound, the synthetic route is as follows.

To a solution of 2-(methylthio)oxazolo[4,5-b]pyri- dine (2.0 g, 12.12 mmol) in THF (5 mL) was added morpholine (5 mL) and heated at 75 C. overnight. The solvent was distilled off to afford the title compound (2.0 g, 83.3%).10210] ?HNMR (DMSO-d5, 300 MHz): oe 8.20-8.10 (d,1H), 7.80-7.70 (d, 1H), 7.15-7.00 (m, 1H), 3.75-3.72 (m,4H), 3.63-3.52 (m, 4H). LCMS: mlz: 206.5 (M+1)+

The chemical industry reduces the impact on the environment during synthesis 169205-95-2, I believe this compound will play a more active role in future production and life.

Reference:
Patent; AURIGENE DISCOVERY TECHNOLOGIES LIMITED; Gummadi, Venkateshwar Rao; Samajdar, Susanta; (82 pag.)US2016/340366; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem