Category: 1702-17-6

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1702-17-6, name is 3,6-Dichloropicolinic acid, the common compound, a new synthetic route is introduced below. HPLC of Formula: C6H3Cl2NO2

Under a nitrogen atmosphere, (Purity: 95.1 wt%) of 3,6-dichloropyridine-2-carboxylic acid, 63 g of toluene and 0.48 g of N, N-dimethylformamide was added dropwise at 80 C over 0.5 hour And 17.04 g of thionyl chloride was added thereto, followed by stirring at the same temperature for 1.5 hours. The reaction mixture was cooled to 50 C and concentrated under reduced pressure to give 47.67 g of a toluene solution of 3,6-dichloropyridine-2-carboxy chloride (confirmed by mixing the reaction mixture with methanol).

The synthetic route of 1702-17-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; KIMURA, TAKAHIRO; MAEHATA, RYOTA; (41 pag.)TW2016/5803; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1702-17-6, name is 3,6-Dichloropicolinic acid. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C6H3Cl2NO2

EXAMPLE 7 3,6-bis(n-hexylthio)-2-pyridinecarboxylic acid To 300 ml of DMSO was added 84.5 g of powdered NaOH with vigorous stirring followed by the addition of 150 g of n-hexyl mercaptan. The anion of the mercaptan was allowed to form and then 111 g of 3,6-dichloro-2-pyridinecarboxylic acid in 110 ml of DMSO was added through a dropping funnel. the temperature was increased during addition to 135 C. and maintained at that temperature for 21/2 hours. Upon cooling the brown solution was poured into three volumes of water. The resulting solution was acidified with HCl and extracted with 1,1,1-trichloroethane. The organic layer was dried over MgSO4 and the solvent removed on a rotary evaporator. The reaction yielded 155 g (68% yield) of 3,6-bis(n-hexylthio)-2-pyridinecarboxylic acid as a dark oil which solidified on standing; m.p. 40-42 C.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 1702-17-6, 3,6-Dichloropicolinic acid.

Reference:
Patent; The Dow Chemical Company; US4371537; (1983); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1702-17-6, name is 3,6-Dichloropicolinic acid, the common compound, a new synthetic route is introduced below. Recommanded Product: 3,6-Dichloropicolinic acid

Under a nitrogen atmosphere, (Purity: 95.1 wt%) of 3,6-dichloropyridine-2-carboxylic acid, 63 g of toluene and 0.48 g of N, N-dimethylformamide was added dropwise at 80 C over 0.5 hour And 17.04 g of thionyl chloride was added thereto, followed by stirring at the same temperature for 1.5 hours. The reaction mixture was cooled to 50 C and concentrated under reduced pressure to give 47.67 g of a toluene solution of 3,6-dichloropyridine-2-carboxy chloride (confirmed by mixing the reaction mixture with methanol).

The synthetic route of 1702-17-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; KIMURA, TAKAHIRO; MAEHATA, RYOTA; (41 pag.)TW2016/5803; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1702-17-6, name is 3,6-Dichloropicolinic acid. This compound has unique chemical properties. The synthetic route is as follows. Product Details of 1702-17-6

EXAMPLE 7 3,6-bis(n-hexylthio)-2-pyridinecarboxylic acid To 300 ml of DMSO was added 84.5 g of powdered NaOH with vigorous stirring followed by the addition of 150 g of n-hexyl mercaptan. The anion of the mercaptan was allowed to form and then 111 g of 3,6-dichloro-2-pyridinecarboxylic acid in 110 ml of DMSO was added through a dropping funnel. the temperature was increased during addition to 135 C. and maintained at that temperature for 21/2 hours. Upon cooling the brown solution was poured into three volumes of water. The resulting solution was acidified with HCl and extracted with 1,1,1-trichloroethane. The organic layer was dried over MgSO4 and the solvent removed on a rotary evaporator. The reaction yielded 155 g (68% yield) of 3,6-bis(n-hexylthio)-2-pyridinecarboxylic acid as a dark oil which solidified on standing; m.p. 40-42 C.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 1702-17-6, 3,6-Dichloropicolinic acid.

Reference:
Patent; The Dow Chemical Company; US4371537; (1983); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1702-17-6, name is 3,6-Dichloropicolinic acid, molecular formula is C6H3Cl2NO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Quality Control of 3,6-Dichloropicolinic acid

To a solution of compound 1(100 g, 520.8 mmol) in EtOH (400 mL) was added drop- wise SOd2 (155 g, 1.3 mol) at 0 C Then the mixture was stirred at 90 C for 2 h. TLC(PE:EA=3:1, Rf =0.5) showed the reaction was completed. The solvent was evaporated underreduced pressure. The mixture was add saturated NaHCO3 adjusted PH=7 and extracted with EA (200 ml*3). The combined organic layer was dried with Na2SO4, filtered and concentrated to give compound (120 g, 100%) as yellow oil. LC-MS (M+H) =220.

With the rapid development of chemical substances, we look forward to future research findings about 1702-17-6.

Reference:
Patent; BEIGENE, LTD.; WANG, Hexiang; ZHANG, Guoliang; GUO, Yunhang; REN, Bo; WANG, Zhiwei; ZHOU, Changyou; (219 pag.)WO2016/161960; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Related Products of 1702-17-6, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1702-17-6, name is 3,6-Dichloropicolinic acid. A new synthetic method of this compound is introduced below.

M. 5-[(ADAMANTAN- 1-YLMETHYL)-CARB AMOYL]-6-CHLORO-IMIDAZO[1,2-lambda]PYRIDINE-2- CARBOXYLIC ACID ETHYL ESTER; Step 1. S.6-Dichloro-pyridine^-carboxylic acid (adamantan-1-ylmethyl)-amide; A mixture of 3,6-dichloro-pyridine-2-carboxylic acid (1.92 g, 0.01 mol), 1- admantylmethylamine (1.65 g, 0.01 mol), TEA (2.02 g, 0.02 mol) and DMC (2.03 g, 0.012 mol) inDCM (20 mL) is stirred at RT for 2 h. The reaction is quenched with NaHCO3. The organic layer is separated and dried over Na2SO4. Silica gel chromatography (hexanes/EtOAc 3:1) gives the title compound.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1702-17-6, its application will become more common.

Reference:
Patent; NEUROGEN CORPORATION; WO2008/66789; (2008); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 1702-17-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1702-17-6, name is 3,6-Dichloropicolinic acid. This compound has unique chemical properties. The synthetic route is as follows.

(Step 1) Synthesis of: 3,6-dichloro-N-(1-methyl-1H-pyrazol-3-yl)pyridine-2-carboxamide; To a pyridine (500 ml) solution of 30 g of 3,6-dichloro-2-pyridinecarboxylic acid were successively added 16.7 g of 1-methyl-1H-pyrazol-3-amine and 38.9 g of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, and the mixture was stirred at room temperature for 3 hours. Pyridine was distilled off under reduced pressure, and 700 ml of water was added to the obtained residue, and the mixture was stirred for 1 hour to crystallize, thereby giving 36.7 g of the title compound as a pale yellow solid.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1702-17-6, 3,6-Dichloropicolinic acid.

Reference:
Patent; Banyu Pharmaceutical Co., Ltd.; EP2236507; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Related Products of 1702-17-6, Adding some certain compound to certain chemical reactions, such as: 1702-17-6, name is 3,6-Dichloropicolinic acid,molecular formula is C6H3Cl2NO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1702-17-6.

10.02 g (50.6 mmol) of 2,2-difluoro-1,3-benzodioxol-5,6-diamine, 12.27 g (63.2 mmol) of 3,6-dichloropyridine-2-carboxylic acid and 9.90 g (50.6 mmol) of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDCI) were stirred in 100 ml of pyridine under argon for 8 h at 120 C. The reaction mixture was freed of solvent under reduced pressure, and the residue was taken up in ethyl acetate and washed with water. The aqueous phase was extracted twice with ethyl acetate, the organic phases were combined, dried over sodium sulphate and then the solvent was distilled off under reduced pressure. The residue was purified by column chromatography using a cyclohexane/ethyl acetate gradient (20:80 to 0:100) as mobile phase. (log P (neutral): 3.20; MH+: 344; 1H-NMR (400 MHz, D6-DMSO) delta ppm: 7.54 (s, 1H), 7.67 (d, 1H), 7.82 (s, 1H), 8.20 (d, 1H), 13.29 (s, 1H).

According to the analysis of related databases, 1702-17-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; BAYER CROPSCIENCE AKTIENGESELLSCHSAFT; FISCHER, RUEDIGER; WILCKE, DAVID; KAUSCH-BUSIES, NINA; HAGER, DOMINIK; ILG, KERSTIN; HOFFMEISTER, LAURA; WILLOT, MATTHIEU; PORTZ, DANIELA; GOERGENS, ULRICH; TURBERG, ANDREAS; (161 pag.)US2018/271099; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem