Category: 17281-59-3

Tominaga, Yoshinori published the artcileSynthesis of 2-methylthioindolizine-3-carbonitriles using nitroketene dithioacetal, Product Details of C7H7ClN2, the publication is Journal of Heterocyclic Chemistry (1988), 25(6), 1745-9, database is CAplus.

The reaction of 1-cyanomethylpyridinium chloride or bromide, with 1,1-bis(methylthio)-2-nitroethylene in the presence of Et₃N in ethanol gave the corresponding 2-methylthioindolizine-3-carbonitrile I (R = H, Ph; R¹ = H, Me, Et; R² = H, Et, Ph, CH₂Ph; R³ = H, Me, Et) and 2-methylthio-1-nitroindolizine-3-carbonitrile in good yields, resp. Compounds I (R-R³ = H; R = R² = H, R¹ = R³ = Me) were key intermediates for the synthesis of cycl[3,2,2]azine derivatives

Journal of Heterocyclic Chemistry published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C11H16BNO3, Product Details of C7H7ClN2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Chatterjea, J. N. published the artcileSynthesis in the 4-azafluorene group. Part III, Safety of 1-(Cyanomethyl)pyridin-1-ium chloride, the publication is Journal of the Indian Chemical Society (1978), 55(2), 149-53, database is CAplus.

Cyclocondensation of benzylideneindandiones I (R = H, Me, MeO, NO₂) with NH₄OAc in the presence of 1-phenacylpyridinium bromide gave the diindenopyridines II. Hantzsch cyclization of 2-benzylidene-1-indanone with PhC(NH₂):CCN gave the dihydroazafluorenone III, which was aromatized by chromic acid, hydrolyzed, and decarboxylated to give the azafluorenone IV (Z = O). Wolff-Kishner reduction of IV (Z = O) gave IV (Z = H₂). Treatment of 2-benzylideneindan-1-one with NH₄OAc and 1-acetonylpyridinium bromide gave 3-methyl-1-phenyl-4-azafluorene, which was also obtained from Et 3-methyl-1-phenyl-4-azafluorenone-2-carboxylate by successive hydrolysis, decarboxylation, and Wolff-Kishner reduction 1-Benzylidene-2-indanone was prepared from Et 3-benzylidene-2-oxo-1-indancarboxylate by hydrolysis-decarboxylation.

Journal of the Indian Chemical Society published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Safety of 1-(Cyanomethyl)pyridin-1-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Das, Rudra Narayan published the artcilePredictive in silico Modeling of Ionic Liquids toward Inhibition of the Acetyl Cholinesterase Enzyme of Electrophorus electricus: A Predictive Toxicology Approach, Synthetic Route of 17281-59-3, the publication is Industrial & Engineering Chemistry Research (2014), 53(2), 1020-1032, database is CAplus.

Chems. are the essential components of the industry for maneuvering the required need of the living ecosystem. Ionic liquids are a group of promising novel chems. with potential usefulness toward various industrial applications, although they are not entirely devoid of hazardous outcomes. The present study is an attempt to investigate the chem. attributes of a wide variety of 292 ionic liquids toward their inhibitory potential of acetyl cholinesterase enzyme of elec. eel through the development of predictive regression and classification-based quant. math. models in the light of the OECD guidelines. Mol. docking studies have addnl. corroborated the results. Hydrophilicity, hydrophobicity, branching, and pos. charged N-species were observed to be the major chem. contributors to such toxicity. The docking studies chiefly portrayed the π-cationic type interaction of the cationic N⁺ atom with the Phe 288, Phe 290, and Trp 23 residues of the acyl binding pocket to be responsible for enzyme inhibition.

Industrial & Engineering Chemistry Research published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Synthetic Route of 17281-59-3.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Costa, Marta published the artcileSynthesis of 3-aminochromenes: the Zincke reaction revisited, Product Details of C7H7ClN2, the publication is Tetrahedron (2014), 70(33), 4869-4875, database is CAplus.

3-(Amino)coumarin derivatives and 2-(imino)-3-chromenamine derivatives were efficiently prepared by a Zincke-reaction-ring-opening reaction of the corresponding 2H-chromene-3-pyridinium chlorides using N-methylpiperazine. This methodol. unravels the marked potential of pyridinium salts as protective groups for primary amines. These scaffolds can be considered important building blocks for N-[7-[[3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L–lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-buten-1-yl)benzamide (novobiocin) analogs and similar heterocyclic compounds The synthesis of the target compounds was achieved by a cyclization (heterocyclization, Zincke reaction) of 2-hydroxybenzoic acid derivatives with 1-(cyanomethyl)pyridinium chloride. The title compounds thus formed included 1-(2-imino-2H-1-benzopyran-3-yl)pyridinium chloride derivatives (chromene-imine derivatives) and 1-(2-oxo-2H-1-benzopyran-3-yl)pyridinium chloride derivatives (coumarin derivatives). These compounds was intermediates for 3-amino-2H-1-benzopyran-2-one derivatives (amine-coumarin derivatives) and 2-(imino)-2H-1-benzopyran-3-amine derivatives

Tetrahedron published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Product Details of C7H7ClN2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Henrick, C. A. published the artcilePyridinium ylides in synthesis. II. Acylation and the synthesis of β-dicarbonyl compounds, Safety of 1-(Cyanomethyl)pyridin-1-ium chloride, the publication is Australian Journal of Chemistry (1967), 20(11), 2455-65, database is CAplus.

The acylation of N-pyridinium ylides with acid chlorides or anhydrides yields C-acylated ylides which may be reductively cleaved to yield β-diketones or β-keto esters, depending on the starting materials. The uv, ir, and N.M.R. spectra of the ylides are discussed. 34 references.

Australian Journal of Chemistry published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Safety of 1-(Cyanomethyl)pyridin-1-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Fischer, Eberhard published the artcilePreparation and reactions of pyridinium betaines, HPLC of Formula: 17281-59-3, the publication is Zeitschrift fuer Chemie (1978), 18(4), 137-8, database is CAplus.

Reaction of the pyridinium compounds I (R = H, Me) with R¹NCS (R¹ = Et, Ph, 4-ClC₆H₄) gave the betaines II, which reacted with R²COCl (R² = Ph, 2-, 3-O₂NC₆H₄, 3,4-Cl₂C₆H₃, CH₂Cl, OMe, COCl) to give the pyridinum chlorides III.

Zeitschrift fuer Chemie published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, HPLC of Formula: 17281-59-3.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Alvarez-Builla, Julio published the artcileUse of dipolar species under phase-transfer catalysis. Part 1. 1,3-Dipolar cycloaddition in a two-phase system, Application In Synthesis of 17281-59-3, the publication is Journal of Chemical Research, Synopses (1984), 202-3, database is CAplus.

Eleven indolizines were prepared in 18-82% yield by 1,3-dipolar cycloaddition of pyridinium ylides with RCCCO₂Me (R = MeO₂C, Ph) in a 2-phase system. Addition of MeO₂CCCCO₂Me to N-(methoxycarbonylmethyl)pyridinium chloride and KOH, supported on alumina (1:1) suspended in MeCN, at room temperature for >18 h, followed by dehydrogenation with 5% Pd-C at reflux for 4 h gave 44% indolizine I. Phase-transfer catalysts did not significantly improve the yields.

Journal of Chemical Research, Synopses published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Application In Synthesis of 17281-59-3.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Jiang, Nan published the artcilePerdeuterated pyridinium molten salt (ionic liquid) for direct dissolution and NMR analysis of plant cell walls, Category: pyridine-derivatives, the publication is Green Chemistry (2009), 11(11), 1762-1766, database is CAplus.

A bi-solvent system consisting of perdeuterated pyridinium molten salt and DMSO-d₆ has been developed for direct dissolution and NMR anal. of plant cell walls, which will shed a new light on efficient detailed structure of the plant cell walls and benefit lignin engineering for biofuel and biomaterial research.

Green Chemistry published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Jiang, Nan published the artcileDirect dissolution and NMR analysis of the plant cell walls via perdeuterated pyridinium-based ionic liquid, HPLC of Formula: 17281-59-3, the publication is Preprints of Symposia – American Chemical Society, Division of Fuel Chemistry (2010), 55(1), 235-236, database is CAplus.

This article presents the perdeuterated pyridinium ionic liquid system for direct dissolution and NMR anal. of the Wiley milled and ball-milled plant cell walls to reveal the detailed structure of the plant cell walls. The unique properties and easy preparation of pyridinium-based ionic liquid [Hpyr]Cl-d₆ offer significant benefits over imidazolium-based ionic liquids for NMR characterization of the non-ball-milled plant cell walls. Further applications of this novel ionic liquid-based solvent system include the determination of lignin content, H:S:G ratios and inter-unit lignin bonding arrangements, without the need for lengthy lignin isolation procedures.

Preprints of Symposia – American Chemical Society, Division of Fuel Chemistry published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, HPLC of Formula: 17281-59-3.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Costa, Marta published the artcileSelective synthesis of some imidazopyridine-fused chromones, Related Products of pyridine-derivatives, the publication is Tetrahedron (2011), 67(45), 8622-8627, database is CAplus.

A fused heterocyclic scaffold combining the imidazo[1,2-a]pyridine with a substituted chromone was synthesized in a one-pot procedure. The reaction proceeds by intramol. cyclization of 1-(2-imino-2H-chromen-3-yl)pyridinium chloride in ethanol and in the presence of DABCO. A detailed study of the exptl. conditions allowed a clear understanding of the reaction pathway.

Tetrahedron published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem