Category: 1991/2/1

Cappello, Daniela published the artcileA Boron Difluoride Hydrazone (BODIHY) Polymer Exhibits Aggregation-Induced Emission, COA of Formula: C12H9NO, the publication is Macromolecular Rapid Communications (2021), 42(8), 2000553, database is CAplus and MEDLINE.

Polymers that exhibit aggregation-induced emission (AIE) find use, for example, as cell-imaging agents and as fluorometric sensors due to their unique optical properties. However, the structural diversity of AIE-active polymers has not necessarily advanced at the same rate as their applications. In this work, ring-opening metathesis polymerization is used to synthesize the first example of a polymer (M_n = 61,600 g mol^-1, Dj = 1.32) containing boron difluoride hydrazone (BODIHY) heterocycles in its repeating unit. The BODIHY monomer and polymer described absorb and emit in the visible region in solution (λ_abs = 428 and 429 nm, λ_em = 528 and 526 nm) and as thin films (λ_abs = 443 and 440 nm, λ_em = 535 and 534 nm). Monomer (Φ_Film = 10%) and polymer (Φ_Film = 6%) exhibit enhanced emission as thin films compared to solution (Φ_Soln â‰?1%) as well as AIE upon the addition of water to DMF solutions as a result of restriction of intramol. motion. Enhancement factors for the monomer and polymer are determined to be 58 and 15, resp. The title BODIHY polymer exhibited an earlier onset of AIE and enhanced sensitivity to solution viscosity when compared to the parent monomer.

Macromolecular Rapid Communications published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, COA of Formula: C12H9NO.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Nan, Xiao-Lei published the artcileSite-selective D₂O-mediated deuteration of diaryl alcohols via quantum dots photocatalysis, COA of Formula: C12H9NO, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(55), 6768-6771, database is CAplus and MEDLINE.

Owing to the high synthetic value of deuteration in the pharmaceutical industry, the conversion of a range of aromatic ketones to deuterium-labeled products such as RR¹CD(OH) [R = Ph, 4-ClC₆H₄, 4-BrC₆H₄, 4-CNC₆H₄, 4-PhC₆H₄; R¹ = Ph, 2-thienyl, 2-naphthyl, etc.] in good to excellent yields was described. Efficient and site-selective deuteration of benzyl alcs. by D₂O with visible light irradiation of quantum dots (QDs), together with gram-scale synthesis and photocatalyst recycling experiments indicated the potential of the developed method in practical organic synthesis.

Chemical Communications (Cambridge, United Kingdom) published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, COA of Formula: C12H9NO.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zhang, Xinyu published the artcileSelenium atoms induce organic doped systems to produce pure phosphorescence emission, Computed Properties of 91-02-1, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(8), 1179-1182, database is CAplus and MEDLINE.

A host-guest system is constructed using a guest containing two selenium atoms. The selenium atoms can increase the spin-orbit coupling constant and the conjugation degree, thereby increasing the emission wavelength, and making the materials show only phosphorescence emission.

Chemical Communications (Cambridge, United Kingdom) published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C10H15NO, Computed Properties of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Musci, Pantaleo published the artcileFlow technol. for telescoped generation, lithiation and electrophilic (C₃) functionalization of highly strained 1-azabicyclo[1.1.0]butanes, SDS of cas: 91-02-1, the publication is Angewandte Chemie, International Edition (2021), 60(12), 6395-6399, database is CAplus and MEDLINE.

Strained compounds are privileged moieties in modern synthesis. In this context, 1-azabicyclo[1.1.0]butanes are appealing structural motifs that can be employed as click reagents or precursors to azetidines. We herein report the first telescoped continuous flow protocol for the generation, lithiation, and electrophilic trapping of 1-azabicyclo[1.1.0]butanes. The flow method allows for exquisite control of the reaction parameters, and the process operates at higher temperatures and safer conditions with respect to batch mode. The efficiency of this intramol. cyclization/C3-lithiation/electrophilic quenching flow sequence is documented with more than 20 examples.

Angewandte Chemie, International Edition published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, SDS of cas: 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Martinez, Thibaut published the artcileIndolizy Carbene Ligand. Evaluation of Electronic Properties and Applications in Asymmetric Gold(I) Catalysis, Synthetic Route of 91-02-1, the publication is Angewandte Chemie, International Edition (2021), 60(36), 19879-19888, database is CAplus and MEDLINE.

We report herein a new family of carbene ligands based on an indolizine-ylidene (Indolizy) moiety. The corresponding gold(I) complexes are easily obtained from the gold(I)-promoted cyclization of allenylpyridine precursors. Evaluation of the electronic properties by exptl. methods and also by DFT calculations confirms strong σ-donating and π-accepting properties of these ligands. Cationization of the gold(I) complexes generates catalytic species that trigger diverse reactions of (poly)unsaturated precursors. When armed with a methylene phosphine oxide moiety on the stereogenic center adjacent to the nitrogen atom, the corresponding bifunctional carbene ligands give rise to highly enantioselective heterocyclizations. DFT calculations brought some rationalization and highlighted the critical roles played by the phosphine oxide group and the tosylate anion in the asym. cyclization of γ-allenols.

Angewandte Chemie, International Edition published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Synthetic Route of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Czyz, Milena L. published the artcileReductive Activation and Hydrofunctionalization of Olefins by Multiphoton Tandem Photoredox Catalysis, Related Products of pyridine-derivatives, the publication is ACS Catalysis (2021), 11(9), 5472-5480, database is CAplus.

The conversion of olefin feedstocks to architecturally complex alkanes represents an important strategy in the expedient generation of valuable mols. for the chem. and life sciences. Synthetic approaches are reliant on the electrophilic activation of unactivated olefins, necessitating functionalization with nucleophiles. However, the reductive functionalization of unactivated and less activated olefins with electrophiles remains an ongoing challenge in synthetic chem. Here, we report the nucleophilic activation of inert styrenes through a photoinduced direct single electron reduction to the corresponding nucleophilic radical anion. Central to this approach is the multiphoton tandem photoredox cycle of the iridium photocatalyst [Ir(ppy)₂(dtb-bpy)]PF₆, which triggers in situ formation of a high-energy photoreductant that selectively reduces styrene olefinic π bonds to radical anions without stoichiometric reductants or dissolving metals. This mild strategy enables the chemoselective reduction and hydrofunctionalization of styrenes to furnish valuable alkane and tertiary alc. derivatives Mechanistic studies support the formation of a styrene olefinic radical anion intermediate and a Birch-type reduction involving two sequential single electron transfers. Overall, this complementary mode of olefin activation achieves the hydrofunctionalization of less activated alkenes with electrophiles, adding value to abundant olefins as valuable building blocks in modern synthetic protocols.

ACS Catalysis published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Hayashi, Eri published the artcileBase-Assisted Aerobic C-H Oxidation of Alkylarenes with a Murdochite-Type Oxide Mg₆MnO₈ Nanoparticle Catalyst, Safety of Phenyl(pyridin-2-yl)methanone, the publication is ACS Applied Materials & Interfaces (2022), 14(5), 6528-6537, database is CAplus and MEDLINE.

Heterogeneously catalyzed aerobic oxidative C-H functionalization under mild conditions is a chem. process to obtain desired oxygenated products directly. Nanosized murdochite-type oxide Mg₆MnO₈ (Mg₆MnO₈-MA) was successfully synthesized by the sol-gel method using malic acid. The sp. surface area reached up to 104 m² g^-1, which is about 7 times higher than those (2-15 m² g^-1) of Mg₆MnO₈ synthesized by previously reported methods. Mg₆MnO₈-MA exhibited superior catalytic performance to those of other Mn- and Mg-based oxides, including manganese oxides with Mn-O-Mn active sites for the oxidation of fluorene with mol. oxygen (O₂) as the sole oxidant under mild conditions (40°C). The present catalytic system was applicable to the aerobic oxidation of various substrates. The catalyst could be recovered by simple filtration and reused several times without obvious loss of its high catalytic performance. The correlation between the reactivity and the pK_a of the substrates, basic properties of catalysts, and kinetic isotope effects suggest a basicity-controlled mechanism of hydrogen atom transfer. The ¹⁸O-labeling experiments, kinetics, and mechanistic studies showed that H abstraction of the hydrocarbon proceeds via a mechanism involving O₂ activation. The structure of Mg₆MnO₈ consisting of isolated Mn⁴⁺ species located in a basic MgO matrix plays an important role in the present oxidation

ACS Applied Materials & Interfaces published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Safety of Phenyl(pyridin-2-yl)methanone.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Hou, Chuanfu published the artcileVisible-Light-Induced Decarboxylative Acylation of Pyridine N-Oxides with α-Oxocarboxylic Acids Using Fluorescein Dimethylammonium as a Photocatalyst, HPLC of Formula: 91-02-1, the publication is Advanced Synthesis & Catalysis (2021), 363(11), 2806-2812, database is CAplus.

The development of a visible-light-induced catalytic system achieved the decarboxylative acylation of pyridine N-oxides with α-oxocarboxylic acids, at room temperature and using the organic dye fluorescein dimethylammonium as a new type of photocatalyst was reported. A series of 2-arylacylpyridine N-oxides were selectively synthesized in moderate to good yields by controlling the polarity of the reaction solvent. The developed strategy was successfully applied in the synthesis of an important intermediate of the drug, acrivastine, on a gram scale. Notably, this is the first time that fluorescein dimethylammonium was used to catalyzed the Minisci-type C-H decarboxylative acylation reaction. The mechanism of decarboxylative acylation was studied by capturing adducts of acyl radicals and 1,1-diphenylethylene confirmed a radical mechanism. The disclosed catalytic system provided a green synthetic strategy for decarboxylative acylation without the use of addnl. oxidants or metal catalysts.

Advanced Synthesis & Catalysis published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, HPLC of Formula: 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Pischedda, Sara published the artcileSynthesis and characterization of new Pd(II) and Pt(II) complexes with 3-substituted 1-(2-pyridyl)imidazo[1,5-a]pyridine ligands, Quality Control of 91-02-1, the publication is Dalton Transactions (2021), 50(14), 4859-4873, database is CAplus and MEDLINE.

Several palladium(II) and platinum(II) complexes (1–20) of general formula [M(Lⁿ)(X)(Y)] [M = Pd, X = Y = Cl (1–Cl–4–Cl), X = Y = OAc (1–OAc–4–OAc); M = Pt: X = Y = Cl (5–8); M = Pd, X = Cl, Y = CH₃ (9–12); M = Pt, X = Cl, Y = CH₃ (13–16) or X = Y = CH₃ (17–20); n = 1-4] have been synthesized by reaction of different Pd(II) and Pt(II) derivatives with various 3-substituted 1-(2-pyridyl)-imidazo[1,5-a]pyridines; i.e. Lⁿ = 1-(2-pyridyl)-3-arylimidazo[1,5-a]pyridine (aryl = Ph, L¹; 2-o-Tolyl, L²; Mesityl, L³) and 1-(2-pyridyl)-3-benzylimidazo[1,5-a]pyridine (L⁴). Detailed spectroscopic investigation (including IR, mono- and bi-dimensional ¹H NMR) and elemental anal. has been performed for all these species, allowing their complete characterization. Lⁿ act as N,N-bidentate ligands and coordinate the metal centers in a chelate fashion through the pyridyl (N_py) and the pyridine-like nitrogen atom of the imidazo[1,5-a]pyridine group (N_im). The x-ray structural anal. performed on two of Pd(II) and three Pt(II) complexes, namely [Pd(L²)(CH₃)Cl] (10), [Pd(L³)(CH₃)Cl] (11) and [Pt(L¹)Cl₂] (5), [Pt(L⁴)Cl₂] (8), [Pt(L²)(CH₃)Cl] (14) confirmed the spectroscopic and anal. data. Finally DFT studies unveiled the structural reasons behind the inertia of the synthesized compounds toward metalation, identified as the higher angle steric strain in comparison with the analogous bipyridine complexes.

Dalton Transactions published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Quality Control of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ju, Zhao-Yang published the artcileSelective Aerobic Oxidation of C_sp³-H Bonds Catalyzed by Yeast-Derived Nitrogen, Phosphorus, and Oxygen Codoped Carbon Materials, COA of Formula: C12H9NO, the publication is Journal of Organic Chemistry (2022), 87(6), 3978-3988, database is CAplus and MEDLINE.

Nitrogen, phosphorus and oxygen codoped carbon catalysts were successfully synthesized using dried yeast powder as pyrolysis precursor. The yeast-derived heteroatom-doped carbon (yeast@C) catalysts exhibited outstanding performance in the oxidation of C_sp3-H bonds to ketones and esters giving excellent products yields (up to 98% yield) without organic solvents at low O₂ pressure (0.1 MPa). The catalytic oxidation protocol exhibited broad range of substrates (38 examples) with good functional group tolerance, excellent regioselectivity and synthetic utility. The yeast-derived heteroatom-doped carbon catalysts showed good reusability and stability after recycle six times without any significant loss of activity. Exptl. results and DFT calculations proved the important role of N-oxide (N⁺-O^–) on the surface of yeast@C and a reasonable carbon radical mechanism.

Journal of Organic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, COA of Formula: C12H9NO.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem