Category: 2098851-48-8

Application of cas: 2098851-48-8 | Wei, Jun et al. published an article in 2019

N-Arylation of a wide range of NH substrates by reaction with boronic acid in the presence of cupric acetate and either triethylamine or pyridine at room temperature. The reaction works even for poorly nucleophilic substrates such as arylamide. So Sodium 5-(trifluoromethyl)pyridine-2-sulfinate(cas: C6H3F3NNaO2S) can also undergo this reaction.Product Details of 2098851-48-8

Wei, Jun;Liang, Huamin;Ni, Chuanfa;Sheng, Rong;Hu, Jinbo published 《Transition-Metal-Free Desulfinative Cross-Coupling of Heteroaryl Sulfinates with Grignard Reagents》. The research results were published in《Organic Letters》 in 2019.Product Details of 2098851-48-8 The article conveys some information:

A mild cross-coupling reaction of heteroaryl sulfinates with Grignard reagents has been developed under transition-metal-free conditions. This study provides an example of the SO22- as a leaving group in an aromatic system and an effective methodol. for the construction of C-C bond.Sodium 5-(trifluoromethyl)pyridine-2-sulfinate (cas: 2098851-48-8) were involved in the experimental procedure.

N-Arylation of a wide range of NH substrates by reaction with boronic acid in the presence of cupric acetate and either triethylamine or pyridine at room temperature. The reaction works even for poorly nucleophilic substrates such as arylamide. So Sodium 5-(trifluoromethyl)pyridine-2-sulfinate(cas: C6H3F3NNaO2S) can also undergo this reaction.Product Details of 2098851-48-8

Reference:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cas: 2098851-48-8 | Markovic, Timpublished an article in 2017

N-Arylation of a wide range of NH substrates by reaction with boronic acid in the presence of cupric acetate and either triethylamine or pyridine at room temperature. The reaction works even for poorly nucleophilic substrates such as arylamide. So Sodium 5-(trifluoromethyl)pyridine-2-sulfinate(cas: C6H3F3NNaO2S) can also undergo this reaction.Recommanded Product: 2098851-48-8

Markovic, Tim;Rocke, Benjamin N.;Blakemore, David C.;Mascitti, Vincent;Willis, Michael C. published 《Pyridine sulfinates as general nucleophilic coupling partners in palladium-catalyzed cross-coupling reactions with aryl halides》. The research results were published in《Chemical Science》 in 2017.Recommanded Product: 2098851-48-8 The article conveys some information:

An efficient procedure was reported for the synthesis of aryl pyridines via Pd-catalyzed desulfinylative cross-coupling of pyridine sulfinates and aryl halides. In addition, these pyridine sulfinates were applied in a library format to the preparation of medicinally relevant derivatives, (6S,10R)-2-(aryl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxalines, I [R = 6-MeO-pyridin-3-yl, 3-pyridyl, 5-Cl-pyridin-2-yl, etc.] of the drug varenicline and N’-(2,2′-biaryl)-N’-(4-methoxybenzyl)-N,N-dimethylethane-1,2-diamines, e.g., II of the drug mepyramine.Sodium 5-(trifluoromethyl)pyridine-2-sulfinate (cas: 2098851-48-8) were involved in the experimental procedure.

N-Arylation of a wide range of NH substrates by reaction with boronic acid in the presence of cupric acetate and either triethylamine or pyridine at room temperature. The reaction works even for poorly nucleophilic substrates such as arylamide. So Sodium 5-(trifluoromethyl)pyridine-2-sulfinate(cas: C6H3F3NNaO2S) can also undergo this reaction.Recommanded Product: 2098851-48-8

Reference:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem