Category: 2176-62-7

Adding a certain compound to certain chemical reactions, such as: 2176-62-7, Perchloropyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: Perchloropyridine, blongs to pyridine-derivatives compound. name: Perchloropyridine

In a 1000 mL three-necked flask, add 600 mL of DMI and anhydrous KF146.72 g with a purity of 99% and a particle size of 20-50 um. Stirring and distilling under reduced pressure (130-135 C / 60 mmHg)60 g solvent with water evaporation, the measured water content of less than 1000 ppm, heated to 90 C, adding purity of 97% of the five chloropyridine 129.40 g, After 1.5 h of incubation, heating was stopped, the reaction mixture was cooled and the reaction mixture was filtered to obtain filtrate and residue. The residue was washed with 100 mL of DMI and suction filtered to obtain a washing solution. Combined washing liquid and filtrate, distillation, collecting 65 ~ 70 , 5 KPa fractions, namely 3,5-dichloro-2,4,6-trifluoropyridine

At the same time, in my other blogs, there are other synthetic methods of this type of compound,2176-62-7, Perchloropyridine, and friends who are interested can also refer to it.

Reference:
Patent; Sichuan Fusida Biotechnology Development Co., Ltd; Luo, Qian; Peng, Zhou; Li, Zhou; Wang, Lei; Zhang, Hua; Pi, Yawei; (8 pag.)CN106008331; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 2176-62-7, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 2176-62-7, name is Perchloropyridine. A new synthetic method of this compound is introduced below.

EXAMPLE II — 2,3,5-Trichloropyridine To a 500 milliliter, 3-neck flask which was fitted with a reflux condenser, heater, thermometer and stirrer was added 200 milliliters (1.2 moles) of 6N ammonium hydroxide, 39.0 grams (0.60 gram atom) of zinc dust, 100 milliliters of toluene and 25.1 grams (0.1 mole) of pentachloropyridine. The pH of the mixture was 12.6. The mixture was heated to 70 C., with stirring, and held under these conditions for 35 hours. At the end of this period, the reaction mixture was cooled to 20 C. and filtered to remove insolubles. The filter cake was washed with toluene and the toluene combined with the filtrate and concentrated by distillation. Analysis indicated a 2,3,5-trichloropyridine yield of 9.39 grams (52 percent of theoretical).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,2176-62-7, its application will become more common.

Reference:
Patent; The Dow Chemical Company; US4111938; (1978); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem