Category: 2215-33-0

March, J. G. published the artcileFluorimetric determination of phytic acid based on the activation of the oxidation of 2,2′-dipyridyl ketone hydrazone catalyzed by Cu(II), Product Details of C11H10N4, the publication is Analyst (Cambridge, United Kingdom) (1999), 124(6), 897-900, database is CAplus and MEDLINE.

Phytic acid exerts an activation effect on the oxidation of 2,2′-dipyridyl ketone hydrazone catalyzed by Cu(II) ion and the oxidation product is highly fluorescent. A fixed time method for the fluorometric determination of phytic acid based on this effect is described. The calibration graph is linear over the range 0.05-0.6 mg L^-1 phytic acid, resulting in a limit of detection of 0.03 mg L^-1 phytic acid. The relative standard deviation is in the range 1.4-1.8%, depending on the sample analyzed. The method was successfully applied to the determination of phytic acid in human urine (20 samples) and food samples (nine different products). The results obtained for urine samples ranged from 0.31 to 3.6 mg L^-1 phytic acid and for food samples from 3.8 to 22 mg g^-1 phytic acid. This is the 1st procedure to be reported for the determination of phytic acid based on fluorometric measurements.

Analyst (Cambridge, United Kingdom) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Product Details of C11H10N4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Abu Zuhri, Ali Z. published the artcilePolarography of pyridine-2-carboxaldehyde 2-pyridylhydrazone in solutions of varying pH at a dropping-mercury electrode: effect of surface-active substance, Safety of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) (1985), 499-502, database is CAplus.

The polarog. behavior of pyridine-2-carboxaldehyde 2-pyridylhydrazone (I) at a dropping-Hg electrode was studied in aqueous Britton-Robinson buffers containing 50% EtOH. The polarograms consist of one wave in the acidic and alk. medium. Two electrons are consumed in the splitting of the N-N bond to give 2-aminopyridine and pyridine-2-carboxaldehyde. The adsorption effects of cationic, anionic, and nonionic surfactants on the polarog. waves of I were investigated. The kinetic parameters for the electrode reaction at different pH values were calculated

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Safety of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Pellerano, C. published the artcileTridentate N-N-N chelating systems as potential antitumoral agents, Computed Properties of 2215-33-0, the publication is Farmaco, Edizione Scientifica (1985), 40(9), 645-54, database is CAplus and MEDLINE.

Tridentate chelating agents were prepared as derivatives of 2-quinolylhydrazine (I; R = H, Me; R¹ = H, Me, MeO; R² = H, Me; R³ = H, Me), 2-pyridylhydrazine (II; R² = H, Me, Ph; R³ = H, Me), and 2-benzothiazolylhydrazine (III; R² = H, Me, Ph; R³ = H, Me) and tested for antitumor activity in mice bearing lymphocytic leukemia P388. Several of the compounds, including 1-(4‘-methyl-2‘-quinolyl)-3-(2‘-pyridyl)-1,2-diaza-2-propene  [71508-71-9], showed some activity against lymphocytic leukemia P388 in mice; the latter compound, however, was inactive when tested against other tumors.

Farmaco, Edizione Scientifica published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Computed Properties of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Pellerano, C. published the artcileQuinolylhydrazones of acetylpyridines: synthesis and biological activity. Part VII, Quality Control of 2215-33-0, the publication is Bollettino Chimico Farmaceutico (1978), 117(12), 721-30, database is CAplus and MEDLINE.

The condensation of acetylpyridine isomers with hydrazinoquinoline isomers yielded hydrazones I (R = H, Me, OMe, Cl; R¹ = H, Me), which exhibited bactericidal and tuberculostatic activity.

Bollettino Chimico Farmaceutico published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Quality Control of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Seydel, Joachim Karl published the artcileDevelopment of effective drug combinations for the inhibition of multiply resistant mycobacteria, especially of the Mycobacterium avium complex, Computed Properties of 2215-33-0, the publication is Chemotherapy (Basel, Switzerland) (1992), 38(3), 159-68, database is CAplus and MEDLINE.

Rationally designed combinations of rifampicin (RAMP) and thiacetazone plus isonicotinic acid hydrazide and/or ethambutol are highly effective in the treatment of patients (including HIV-pos.) infected with multiply resistant mycobacteria of the M. avium complex (MAC). Clin. results are very promising. The high efficacy of these combinations is due to the synergistic potentiation of single-drug activities. As soon as rifabutin is marketed, it should replace RAMP in the combination treatment of patients with highly RAMP-resistant MAC bacteria.

Chemotherapy (Basel, Switzerland) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is 0, Computed Properties of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Odashima, Tsugikatsu published the artcileSynthesis and properties of 3-, 4-, and 5-nitro-2-pyridinecarboxaldehyde 2-pyridylhydrazones and characterization of their metal complexes, Synthetic Route of 2215-33-0, the publication is Bulletin of the Chemical Society of Japan (1993), 66(3), 797-803, database is CAplus.

Three title hydrazones (I, R = 3-, 4-, and 5-NO₂), were synthesized. Their properties and reactivities with metal ions and the extraction and characteristics of the resultant complexes were investigated and compared with one another. As a result, useful information on the mol. design of highly sensitive hydrazone reagents was obtained.

Bulletin of the Chemical Society of Japan published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Synthetic Route of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Taya, Toshiki published the artcileComplexation behavior of heterocyclic hydrazones. I. Structure and acid-base equilibria for heterocyclic hydrazones, Application In Synthesis of 2215-33-0, the publication is Bulletin of the Chemical Society of Japan (1993), 66(12), 3652-61, database is CAplus.

The acid-base equilibrium of twenty-one hydrazones substituted by Ph, pyridyl and/or quinolyl groups have been investigated in aqueous solutions over the region of H_– to H₀ acidity function by a spectrophotometric method at 25 °C. For 2-pyridinecarbaldehyde 2-(5-substituted)pyridylhydrazones, although the proton dissociation of the neutral species (HL) satisfied a Hammett correlation, those of H₂L⁺ and H₃L²⁺ did not. The thermodn. parameters for the proton dissociations of H₂L⁺ of seven representative ligands were determined by a temperature-coefficient method at 25 °C and an ionic strength of 0.1 (KCl). The enthalpy and entropy changes for the proton dissociations of H₃L²⁺ and H₂L⁺ were influenced by the steric effects of the Me group and/or the introduced quinolyl ring. An anal. of the pH dependence of the ¹H NMR signals for three hydrazones in an acetone-d₆-D₂O solution gave more profitable information concerning the fine structures of HL, H₂L⁺, and H₃L²⁺. Each ¹H and ¹³C NMR chem. shift of some ring-substituted Me derivatives (HL form) in a dioxane-D₂O solution has been briefly assigned. On the other hand, a single-crystal X-ray anal., ¹H NMR data in chloroform-d and thermodn. data for di-2-pyridyl ketone 2-pyridylhydrazone (DPPH) suggested that the intramol. hydrogen bond in the DPPH mol. is broken by the addition of a proton on the H₂L⁺ species in an aqueous solution

Bulletin of the Chemical Society of Japan published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C10H10O2, Application In Synthesis of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bell, Colin Frank published the artcileComplexes between pyridine-2-aldehyde-2′-pyridylhydrazone and the platinum metals. I. Rhodium, Formula: C11H10N4, the publication is Inorganic Chemistry (1968), 7(2), 325-9, database is CAplus.

Mono, bis, and tris complexes of Rh(III) and pyridine-2-aldehyde-2′-pyridylhydrazone have been prepared and studied. In all three, the H atom of the imino group of the ligand shows marked acidity associated with coordination to a tripos. metal. The ligand is tridentate in the mono and bis complexes but bidentate in the tris complex. Possible geometrical isomers of this are discussed and its probable structure is described. 17 references.

Inorganic Chemistry published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Formula: C11H10N4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bell, Colin Frank published the artcileComplexes between pyridine-2-carboxaldehyde 2′-pyridylhydrazone and the platinum metals. II. Iridium, Synthetic Route of 2215-33-0, the publication is Inorganic Chemistry (1969), 8(1), 161-3, database is CAplus.

Aqueous (NH4)3(IrCl6) was refluxed with pyridine-2-carboxaldehyde 2′-pyridylhydrazone (HL) in CHCl3 to form [Ir(HL)3]. Also prepared were [IrCl2(HL)]ClO4.2H2O, [IrCl2pyL], and [IrCl3py(HL)] (I), where I is the 1,2,6-isomer. The complexes were characterized by absorption spectra, ir. spectra, and conductance measurements. HL appears to behave as a bidentate ligand in the complexes except in the case of [IrCl2pyL] where it is tridentate.

Inorganic Chemistry published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Synthetic Route of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Brook, David J. R. published the artcileStrong ferromagnetic metal-ligand exchange in a nickel bis(3,5-dipyridylverdazyl) complex, Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Chemical Communications (Cambridge, United Kingdom) (2010), 46(35), 6590-6592, database is CAplus and MEDLINE.

A new 1,5-dipyridyl verdazyl, synthesized from the corresponding dipyridyl hydrazone, coordinates nickel(II) to form a structurally characterized, pseudooctahedral complex analogous to Ni(terpy)₂²⁺. The unusually short Ni-verdazyl distance results in strong ferromagnetic exchange (J_Ni-rad = +300, J_rad-rad = +160 cm^-1) between all three paramagnetic species along with a metal-ligand charge transfer band in the electronic spectrum.

Chemical Communications (Cambridge, United Kingdom) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem