Category: 22280-62-2

Deady, Leslie W.; Korytsky, Olga L.; Rowe, Jeffrey E. published the artcile< Substituent effects on the isomer ratios in the rearrangement of some 2- and 4-nitraminopyridines>, Category: pyridine-derivatives, the main research area is substituent effect rearrangement nitraminopyridine.

The preparation and rearrangement in 92% H2SO4 of I-III (R = H, Me, MeO, Br, Cl, CO2H) were investigated. The product isomer ratios can be explained by differential electronic stabilization of the appropriate σ complexes for aromatic nitration and steric effects seem relatively unimportant. Deuteration [3-D in I, R = Me] had no effect on the product distribution.

Australian Journal of Chemistry published new progress about Rearrangement. 22280-62-2 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Babaev, Eugene V.; Rybakov, Victor B. published the artcile< Phenacylation of 6-methyl-beta-nitropyridin-2-ones and further heterocyclization of products>, SDS of cas: 22280-62-2, the main research area is betanitropyridinone phenacylation; phenacylpyridone heterocyclization; 8-nitro-5-RO-indolizines; Phenacylation of beta-nitropyridin-2-ones; oxazole-pyrrole ring transformation.

Reaction between the derivatives of 6-methyl-beta-nitropyridin-2-one and phenacyl bromides was studied, and the yields observed were extremely low. The pyridones were converted via chloropyridines to methoxyderivatives, which were N-phenacylated. N-Phenacyl derivatives of 4,6-dimethyl-5-nitropyridin-2-one under the action of base gave 5-hydroxy-8-nitroindolizine and under acidic conditions gave 5-methyl-6-nitrooxazole[3,2-a]pyridinium salt, which underwent recyclization with MeONa to 5-methoxy-8-nitroindolizine.

Molecules published new progress about Acylation. 22280-62-2 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, SDS of cas: 22280-62-2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kress, Thomas J.; Moore, Larry L.; Costantino, Silvio M. published the artcile< Selective chlorinations in sulfuric acid. Synthesis of some 2-amino-5-chloro-, 2-amino-3-chloro-, and 2-amino-3,5-dichloropyridines>, Application In Synthesis of 22280-62-2, the main research area is pyridine amino chlorination; chlorination aminopyridine sulfuric acid.

Addnl. data considered in abstracting and indexing are available from a source cited in the original document. 2-Aminopyridine and a number of Me substituted 2-aminopyridines underwent selective chlorination. The chlorination of 2-aminopyridine at various H2SO4 concentrations and the distribution of chlorinated products was studied in detail. With increasing acidity dichlorination decreases, and in 72% H2SO4 only traces of dichlorination occur. The selectivity of the chlorination reaction is ascribed to differences in the rate of chlorination of protonated vs nonprotonated substrates.

Journal of Organic Chemistry published new progress about Chlorination. 22280-62-2 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Application In Synthesis of 22280-62-2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem