Category: 2402-78-0

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 2402-78-0, name is 2,6-Dichloropyridine. This compound has unique chemical properties. The synthetic route is as follows. category: pyridine-derivatives

According to Table 1, the corresponding 2,6-dichloropyridine, alkyl alcohol,Sodium hydroxide is added to a 250ml or 500ml three-necked flask equipped with a reflux condenser, a stirrer, and a thermometer, and heated to boiling with stirring to maintain reflux.The reaction was sampled for 1 hour and the reaction product was found to be 6-chloro-2-alkoxypyridine, abbreviated as pyridine ether.

With the rapid development of chemical substances, we look forward to future research findings about 2402-78-0.

Reference:
Patent; Shandong Kunda Biological Technology Co., Ltd.; Zhao Zengguo; Wang Jiangtao; Song Cailing; Chen Jialiang; Chen Kaiqing; (7 pag.)CN107954928; (2018); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Electric Literature of 2402-78-0 , The common heterocyclic compound, 2402-78-0, name is 2,6-Dichloropyridine, molecular formula is C5H3Cl2N, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

A solution of n-BuLi (21.1 ml_, 33.8 mmol, 1.6 M) in THF is cooled to -78C before a solution of 2,6-dichloropyhdine (5.0 g, 33.8 mmol) in THF (36 ml_) is added dropwise over a period of 20 min. The reaction mixture is stirred at -78C for 30 min, and then iodomethane (4.79 g, 33.8 mmol) is added. The mixture is stirred for 30 min before it is quenched with sat. aq. NH4CI solution at -78C. The mixture is extracted with diethyl ether, the org. extract is dried over MgSO4, filtered and concentrated. The crude product is purified by CC on silica gel eluting with heptane:EA 19:1 to give 2,6-dichloro-4-methyl-pyridine (2.34 g) as a colourless oil containing the regio isomer 2,6-dichloro-3-methyl-pyhdine; LC-MS: tR = 0.89 min, [M+1]+ = 161.97.

The synthetic route of 2402-78-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ACTELION PHARMACEUTICALS LTD; WO2009/24905; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Name: 2,6-Dichloropyridine2402-78-0, Name is 2,6-Dichloropyridine, SMILES is ClC1=CC=CC(Cl)=N1, belongs to pyridine-derivatives compound. In a article, author is Tahmasby, Maryam, introduce new discover of the category.

Pyrido triazin-nucleus synthesis and theoretical studies: 2,3,6-trioxo-8-aryl-1,3,4,6-tetrahydro-]2H[pyrido]1,2-b][1,2,4[triazin-7,9-dicarbonitryl derivatives

An efficient method for the synthesis of potentially biologically [2H]-pyrido [1,2-b]1,2,4-triazines derivatives is described via reaction of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives with oxalyl chloride in DMF in the presence of pyridine as a base. The intramolecular hydrogen bonding (IMHB) interactions have been investigated at M06-2X/6-311 ++ G(d,p) level of theory. The eight compounds (5a-h) characterized by geometries and energies. The Natural bond orbital (NBO) and quantum theory of atoms in molecules (QTAIM) were performed to explore the nature of the hydrogen bonding interactions in these compounds. The IMHB formed between the C = O and N-H groups. The theoretical calculations showed that the IMHB strength increases in the presence of electron-donor substituents. An opposite behavior was observed for electron-acceptor substituents. (c) 2020 Published by Elsevier B.V.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2402-78-0. Name: 2,6-Dichloropyridine.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 2402-78-0, Name is 2,6-Dichloropyridine, molecular formula is , belongs to pyridine-derivatives compound. In a document, author is Goncalves, Fernanda Jorge, Quality Control of 2,6-Dichloropyridine.

Application of pyridine-modified chitosan derivative for simultaneous adsorption of Cu(II) and oxyanions of Cr(VI) from aqueous solution

The bioadsorbent C1, which is a chitosan derivative prepared in a one-step synthesis, was successfully used to adsorb Cr(VI) and Cu(II) simultaneously. Here, for the first time the simultaneous adsorption of a cation and an anion was modeled using the Corsel model for kinetics and the Real Adsorbed Solution Theory model for equilibrium data. Batch studies of the adsorption of Cu(II) and Cr(VI) in single and binary aqueous solutions were performed as a function of initial solute concentration, contact time, and solution pH. The maximum adsorption capacities of C1 in single and binary aqueous solutions were 1.84 and 1.13 mmol g(-1) for Cu(II) and 3.86 and 0.98 mmol g(-1) for Cr(VI), respectively. The reuse of C4 was investigated, with Cu(II) ions being almost completely desorbed and fully re-adsorbed. For Cr(VI), the desorption was incomplete resulting in a lower readsorption. Energy-dispersive X-ray spectroscopy was used for mapping the distributions of Cr(VI) and Cu(II) adsorbed on the C1 surface in single and binary adsorption systems. Isothermal titration calorimetry experiments were performed for Cr(VI) and Cu(II) adsorption in single solutions. The thermodynamic parameters of adsorption showed that the adsorption of both metal ions was enthalpically driven, but entropically unfavorable.

If you are hungry for even more, make sure to check my other article about 2402-78-0, Quality Control of 2,6-Dichloropyridine.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Name: 2,6-Dichloropyridine, 2402-78-0, Name is 2,6-Dichloropyridine, molecular formula is C5H3Cl2N, belongs to pyridine-derivatives compound. In a document, author is Lin, Zeng-Gang, introduce the new discover.

The construction of a novel luminescent lanthanide framework for the selective sensing of Cu2+ and 4-nitrophenol in water

It is challenging to develop highly stable lanthanide luminescent sensors for detecting heavy metal ions and nitroaromatics in view of the human health and environmental security. To this end, two water stable Ln-MOFs with the chemical constitution of {[Ln(HL)]center dot 3DMF center dot 3H(2)O}(n) (Ln = Eu, LZG-Eu and Ln = Tb, LZG-Tb) have been developed solvothermally using a multidentate ligand (H4L) with the central phenyl backbone bisubstituted by 2,6-pyridine-dicarboxylic acid at the para-position, H4L = 1,4-bis(2′,2 ”,6′,6 ”-tetracarboxy-1,4′:4,4 ”-pyridyl)benzene. Single crystal analysis demonstrates that two novel Ln-MOFs feature 4,4,4-connected nets with an unprecedented topology symbol of {4(2).6.8(3)}(2){4(2).6(2).8(2)}{4(2).8(4)} and contain two kinds of one-dimensional channels. Powder X-ray diffraction as well as the luminescence determination results indicate that they retain their crystallinity and structural integrity in harsh acidic and basic conditions with pH in the range of 4-11. Moreover, they are highly luminescent, which makes them excellent chemical sensors for detecting Cu2+ and 4-NP (4-nitrophenol) with high selectivity and sensitivity in aqueous media such as deionized water, tap water, and river water based on distinct quenching effects. To the best of our knowledge, their detection limits are lower than those documented so far. In addition, the quenching efficiency of 4-NP was retained in the presence of interfering ions even after the compounds were used for five cycles, which makes them attractive, reliable, visual, and recyclable luminescent Ln-MOF sensor materials for 4-NP. The recognition mechanism for Cu2+ could be attributed to the dissociation of the main framework induced by Cu2+ and the subsequent formation of a Cu2+ coordination species and that for 4-NP is considered to be multi-quenching mechanisms dominated by competition absorption.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 2402-78-0. Name: 2,6-Dichloropyridine.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Application of 2402-78-0, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 2402-78-0, Name is 2,6-Dichloropyridine, SMILES is ClC1=CC=CC(Cl)=N1, belongs to pyridine-derivatives compound. In a article, author is Dong, Jian-Peng, introduce new discover of the category.

Synthesis of a novel 2D zinc(ii) metal-organic framework for photocatalytic degradation of organic dyes in water

A novel 2D zinc(ii) metal-organic framework, formulated as [Zn(L)(H2O)]H2O (1) (H2L = 4-(pyridine-4-yl) phthalic acid), has been successfully obtained under solvothermal conditions. This metal-organic framework (MOF) material exhibits efficient photocatalytic activity towards the degradation of organic dyes in the absence of any photosensitizer or cocatalyst. Its catalytic performance for rhodamine B (RhB) and methyl orange (MO) degradation was superior to most reported MOFs with a degradation efficiency of 98.5% for RhB and 83.8% for MO within 120 min in the absence of H2O2, which could be attributed to its high efficiency in generating O-2(-) (an effective oxidant for the degradation of dyes). The possible mechanism of the reaction was discussed in detail. In addition, 1 shows stable catalytic efficiency after five reaction cycles, which indicates that 1 exhibits efficient catalytic activity and good reusability toward the degradation of organic dyes, enabling it to be a potential candidate for environmental governance.

Application of 2402-78-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 2402-78-0.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Chemistry, like all the natural sciences, COA of Formula: C5H3Cl2N, begins with the direct observation of nature¡ª in this case, of matter.2402-78-0, Name is 2,6-Dichloropyridine, SMILES is ClC1=CC=CC(Cl)=N1, belongs to pyridine-derivatives compound. In a document, author is El-Gohary, Nasser M., introduce the new discover.

An efficient synthesis of novel heterocyclic systems incorporating coumarin moiety

Polyfunctional 3-chloro-3-(4-chlorocoumarin-3-yl)prop-2-enal (1) used as a precursor for heterocyclic synthesis. Dichloro-aldehyde 1 was allowed to react with variable nucleophilic reagents, and a diversity of heterocyclic systems linked coumarin moiety at position 3 was synthesized. The reaction of compound 1 with guanidine and cyanoguanidine produced 3-(pyrimidin-4-yl)-4-chlorocoumarins 2 and 3. Treating compound 1 with 3-amino-1,2,4-triazole and 2-aminobenzimidazole yielded triazolo[4,3-a]pyrimidine 4 and pyrimido[1,2-a]benzimidazole 5. The treatment of compound 1 with cyanoacetamide, N-benzyl-2-cyanoacetamide, and 1H-benzimidazolylacetonitrile gave 2(1H)-pyridones 6, 7 and pyrido[1,2-a]benzimidazole 8. The reaction of compound 1 with 5-amino-3-methyl-1H-pyrazole and 6-aminouracil afforded pyrazolo[3,4-b]pyridine 9 and pyrido[2,3-d]pyrimidine 10, respectively. Compound 1 reacted with ethylenediamine, o-phenylenediamine, o-aminophenol, and o-aminothiophenol leading to 5-(imidazolylmethyl)chromeno[4,3-e] [1,4]diazepine (12), 3-(benzodiazepin/benzoxazepin-2-yl)-4-chlorocoumarins 13, 14, and 6-(benzothiazol-2-ylmethyl)chromeno[4,3-b][1,5]benzothiazepine 16, respectively. Structures of the new synthesized products were deduced on the basis of their analytical and spectral data.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2402-78-0. COA of Formula: C5H3Cl2N.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2402-78-0, Name is 2,6-Dichloropyridine, SMILES is ClC1=CC=CC(Cl)=N1, belongs to pyridine-derivatives compound. In a document, author is Senthilkumar, Thangaraj, introduce the new discover, SDS of cas: 2402-78-0.

Conjugated Polymer Nanogel Binding Anticancer Drug through Hydrogen Bonds for Sustainable Drug Delivery

Hydrogen-bonded drug conjugation is highly expected as the next-generation smart therapeutic agent that remains stable in biological medium. A carrier design strategy of hydrogen-bonded drug conjugates as pendants in conjugated polymer nanogel is developed. The H-bond acceptor uracil-functionalized poly(p-phenylenevinylene) and 2, 6-diamino pyridine ( H-bond donor)-functionalized doxorubicin (Dox-Py) are synthesized. Further, chemically cross-linked PPV-nanogel with hydrogen-bonded drug complex (PPV-NG/Dox-Py) is fabricated. The presence of triple-point hydrogen bonding in polymer complex as well as in nanogel network is confirmed by H-1 NMR and FT-IR. The hydrophobic microenvironment offered by conjugated polymers backbone stabilizes the hydrogen bonding in the nanogel network. PPV-nanogel/Dox-Py hydrogen-bonded conjugation facilitates higher drug-loading efficiency (82%) and cancer- cell-killing efficiency than encapsulated drug, indicating the superiority of the present design. Sustainable release of Dox-Py is achieved for several days in response to the redox intracellular and acidic environment inside the cancer cells. The proposed hydrogen bond conjugation strategy could provide a broad platform for developing high-value nanotherapeutics.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2402-78-0 is helpful to your research. SDS of cas: 2402-78-0.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Chemistry, like all the natural sciences, Product Details of 2402-78-0, begins with the direct observation of nature¡ª in this case, of matter.2402-78-0, Name is 2,6-Dichloropyridine, SMILES is ClC1=CC=CC(Cl)=N1, belongs to pyridine-derivatives compound. In a document, author is Chatterjee, Basujit, introduce the new discover.

Catalytic dearomative hydroboration of heteroaromatic compounds

This review offers a comprehensive discussion on literature concerning the development of catalytic protocols for the dearomative hydroboration of heteroaromatic compounds. The importance of selective dearomatization of heteroarenes, their remarkable applications along with the development of different catalytic methods and their synthetic scopes are emphasized.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2402-78-0. Product Details of 2402-78-0.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Quality Control of 2,6-Dichloropyridine, 2402-78-0, Name is 2,6-Dichloropyridine, SMILES is ClC1=CC=CC(Cl)=N1, belongs to pyridine-derivatives compound. In a document, author is Zhang, Li, introduce the new discover.

Photoinduced Radical Borylation of Alkyl Bromides Catalyzed by 4-Phenylpyridine

Utilizing pyridine catalysis, we developed a visible-light-induced transition-metal-free radical borylation reaction of unactivated alkyl bromides that features a broad substrate scope and mild reaction conditions. Mechanistic studies revealed a novel nucleophilic substitution/photoinduced radical formation pathway, which could be utilized to trigger a variety of radical processes.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 2402-78-0. Quality Control of 2,6-Dichloropyridine.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem