Category: 24103-75-1

Lougiakis, Nikolaos et al. published their research in Chemical & Pharmaceutical Bulletin in 2008 | CAS: 24103-75-1

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Application In Synthesis of 4-Methoxy-2-methylpyridine

Synthesis and antiviral activity evaluation of some novel acyclic C-nucleosides was written by Lougiakis, Nikolaos;Marakos, Panagiotis;Poul, Nicole;Balzarini, Jan. And the article was included in Chemical & Pharmaceutical Bulletin in 2008.Application In Synthesis of 4-Methoxy-2-methylpyridine This article mentions the following:

The preparation of novel 5-amino or 7-hydroxy substituted pyrazolo[4,3-b]pyridine and pyrazolo[3,4-c]pyridine acyclic C-nucleosides is described. Their synthesis was carried out by condensation of suitably substituted lithiated picolines with 2-benzyloxyethoxymethylchloride followed by pyrazole ring annulation. The compounds were evaluated for their antiviral activity against a wide panel of viruses, but were found inactive at subtoxic concentrations In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Application In Synthesis of 4-Methoxy-2-methylpyridine).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Application In Synthesis of 4-Methoxy-2-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cingolani, G. M. et al. published their research in European Journal of Medicinal Chemistry in 1990 | CAS: 24103-75-1

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Computed Properties of C7H9NO

Indolizine derivatives with biological activity. VI. 1-(2-Aminoethyl)-3-benzyl-7-methoxy-2-methylindolizine, benanserine structural analog was written by Cingolani, G. M.;Claudi, F.;Massi, M.;Venturi, F.. And the article was included in European Journal of Medicinal Chemistry in 1990.Computed Properties of C7H9NO This article mentions the following:

The title compound (I) was prepared from 3-(4-methoxy-2-pyridyl)propionate. In comparison with benanserine I showed greatly reduced antihistaminic activity and somewhat reduced antiserotonin activity whereas the anticholinergic activity remained unaffected. In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Computed Properties of C7H9NO).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Computed Properties of C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hansen, Helge-Boj et al. published their research in Chemistry – A European Journal in 2021 | CAS: 24103-75-1

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Quality Control of 4-Methoxy-2-methylpyridine

The Stronger the Better: Donor Substituents Push Catalytic Activity of Molecular Chromium Olefin Polymerization Catalysts was written by Hansen, Helge-Boj;Wadepohl, Hubert;Enders, Markus. And the article was included in Chemistry – A European Journal in 2021.Quality Control of 4-Methoxy-2-methylpyridine This article mentions the following:

The donor strength of bifunctional pyridine-cyclopentadienyl ligands was altered systematically by the introduction of donating groups in the para-position of the pyridine. In the resulting chromium complexes an almost linear correlation between donor strength and the nitrogen-chromium distance as well as the electronic absorption maximum is exptl. observed The connection of electron-donating groups in the ligand backbone leads to an efficient transfer of the electronic influences to the catalytically active metal center without restricting it through steric effects. Therefore, catalytic olefin polymerization activity, which is already very high for the previously studied catalysts, increase considerably by attaching para-amino groups to the chelating pyridine or quinoline, resp. Combining electron-rich indenyl ligands with para-amino substituted pyridines lead to the highest catalytic activities observed so far for this class of organo chromium olefin polymerization catalysts. The resulting polymers are of ultra-high mol. weight and the ability of the catalysts to incorporate co-monomers is also very high. In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Quality Control of 4-Methoxy-2-methylpyridine).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Quality Control of 4-Methoxy-2-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kubo, Hajime et al. published their research in Biological & Pharmaceutical Bulletin in 2000 | CAS: 24103-75-1

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Safety of 4-Methoxy-2-methylpyridine

The hypoglycemic effect of (7R*,9aS*)-7-phenyl-octahydroquinolizin-2-one in mice was written by Kubo, Hajime;Kobayashi, Junji;Higashiyama, Kimio;Kamei, Junzo;Fujii, Yuji;Ohmiya, Shigeru. And the article was included in Biological & Pharmaceutical Bulletin in 2000.Safety of 4-Methoxy-2-methylpyridine This article mentions the following:

(-)-Multiflorine, which was isolated from leguminous plants, produced a hypoglycemic effect when administered to mice with streptozotocin-induced diabetes. (-)-Multiflorine has an enaminone type conjugation on the A-ring, which is unusual in lupine alkaloids. Proceeding on the assumption that the A-B ring is responsible for the activity, several compounds bearing quinolizidin-2-one were synthesized and their hypoglycemic effects were examined The hypoglycemic effect of (7R*,9aS*)-7-phenyl-octahydroquinolizin-2-one was approx. 4 times stronger than that of (-)-multiflorine measured by oral glucose tolerance test in normal mice. This result indicates that compounds possessing the quinolizidin-2-one ring system as the basic structure may be possible lead compounds for a new type of diabetes drug. In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Safety of 4-Methoxy-2-methylpyridine).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Safety of 4-Methoxy-2-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Deady, L. W. et al. published their research in Australian Journal of Chemistry in 1971 | CAS: 24103-75-1

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 24103-75-1

Synthesis of some substituted methyl pyridinecarboxylates. II. Methyl 4-substituted picolinates, methyl 5-substituted picolinates, and methyl 5-substituted nicotinates was written by Deady, L. W.;Shanks, R. A.;Campbell, Arthur Derek;Chooi, S. Y.. And the article was included in Australian Journal of Chemistry in 1971.Application of 24103-75-1 This article mentions the following:

The preparation of substituted Me pyridinecarboxylates is described. Me 4-X-substituted picolinates and methyl 5-X-substituted picolinates (X = NO2, Br, MeO, Me2N) are prepared from 2-picoline via 4-nitro-2-picoline N-oxide and 2-amino-5-nitropyridine, resp. Me 5-X-substituted nicotinates (X = Br, MeO, Me2N) are prepared from 5-bromonicotinic acid. Preparations of Me 4-methylpicolinate and Me 5-methylnicotinate from the corresponding lutidines and Me 5-methylpicolinate from 2-amino-5-methylpyridine are described. In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Application of 24103-75-1).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 24103-75-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Deady, L. W. et al. published their research in Australian Journal of Chemistry in 1971 | CAS: 24103-75-1

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 24103-75-1

Synthesis of some substituted methyl pyridinecarboxylates. II. Methyl 4-substituted picolinates, methyl 5-substituted picolinates, and methyl 5-substituted nicotinates was written by Deady, L. W.;Shanks, R. A.;Campbell, Arthur Derek;Chooi, S. Y.. And the article was included in Australian Journal of Chemistry in 1971.Application of 24103-75-1 This article mentions the following:

The preparation of substituted Me pyridinecarboxylates is described. Me 4-X-substituted picolinates and methyl 5-X-substituted picolinates (X = NO2, Br, MeO, Me2N) are prepared from 2-picoline via 4-nitro-2-picoline N-oxide and 2-amino-5-nitropyridine, resp. Me 5-X-substituted nicotinates (X = Br, MeO, Me2N) are prepared from 5-bromonicotinic acid. Preparations of Me 4-methylpicolinate and Me 5-methylnicotinate from the corresponding lutidines and Me 5-methylpicolinate from 2-amino-5-methylpyridine are described. In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Application of 24103-75-1).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 24103-75-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem