Adding a certain compound to certain chemical reactions, such as: 2524-52-9, Ethyl 2-picolinate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, COA of Formula: C8H9NO2, blongs to pyridine-derivatives compound. COA of Formula: C8H9NO2
To a solution of 73-3 (5.0 g, 1 equiv.) in EtOH (30 mL) was added NH2NH2H2O (2.5 g, 1.5 equiv.). Then the mixture was heated to reflux and stirred for 16 h. The reaction was completed. The reaction mixture was cooled to room temperature and concentrated to get 4.6 g of crude 73-4.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,2524-52-9, Ethyl 2-picolinate, and friends who are interested can also refer to it.
Reference:
Patent; ANACOR PHARMACEUTICALS, INC.; THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY; JACOBS, Robert Toms; LIU, Yang; SCIOTTI, Richard J.; (0 pag.)WO2018/160845; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem