In an article, author is Jeon, Jinwon, once mentioned the application of 2706-56-1, Name: 2-Pyridylethylamine, Name is 2-Pyridylethylamine, molecular formula is C7H10N2, molecular weight is 122.17, MDL number is MFCD00006367, category is pyridine-derivatives. Now introduce a scientific discovery about this category.
Visible-Light-Induced ortho-Selective Migration on Pyridyl Ring: Trifluoromethylative Pyridylation of Unactivated Alkenes
The photocatalyzed ortho-selective migration on a pyridyl ring has been achieved for the site-selective trifluoromethylative pyridylation of unactivated alkenes. The overall process is initiated by the selective addition of a CF3 radical to the alkene to provide a nucleophilic alkyl radical intermediate, which enables an intramolecular endo addition exclusively to the ortho-position of the pyridinium salt. Both secondary and tertiary alkyl radicals are well-suited for addition to the C2-position of pyridinium salts to ultimately provide synthetically valuable C2-fluoroalkyl functionalized pyridines. Moreover, the method was successfully applied to the reaction with P-centered radicals. The utility of this transformation was further demonstrated by the late-stage functionalization of complex bioactive molecules.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem