Category: 31181-90-5

In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. For this reason, pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Application of C6H4BrNO.

Yang, Bo;Yu, Shang-Bo;Zhang, Pan-Qing;Wang, Ze-Kun;Qi, Qiao-Yan;Wang, Xu-Qing;Xu, Xun-Hui;Yang, Hai-Bo;Wu, Zong-Quan;Liu, Yi;Ma, Da;Li, Zhan-Ting research published 《 Self-Assembly of a Bilayer 2D Supramolecular Organic Framework in Water》, the research content is summarized as follows. Accurate control of the layer number of orderly stacked 2D polymers has been an unsettled challenge in self-assembly. Herein we describe the fabrication of a bilayer 2D supramol. organic framework from a monolayer 2D supramol. organic framework in water by utilizing the cooperative coordination of a rod-like bipyridine ligands to zinc porphyrin subunits of the monolayer network. The monolayer supramol. framework is prepared from the co-assembly of an octacationic zinc porphyrin monomer and cucurbit[8]uril (CB[8]) in water through CB[8]-encapsulation-promoted dimerization of 4-phenylpyridiunium subunits that the zinc porphyrin monomer bear. The bilayer 2D supramol. organic framework exhibits structural regularity in both solution and the solid state, which is characterized by synchrotron small-angle X-ray scattering and high-resolution transmission electron microscopic techniques. Atomic force microscopic imaging confirms that the bilayer character of the 2D supramol. organic framework can be realized selectively on the micrometer scale.

Application of C6H4BrNO, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. SDS of cas: 31181-90-5.

Yang, Chaofu;Feng, Yan;Yang, Xu;Sun, Mingxia;Li, Zhenwang;Liu, Xuan;Lu, Liang;Sun, Xianyu;Zhang, Jiwen;He, Xinhua research published 《 Synthesis and evaluation of 4-(1,3,4-oxadiazol-2-yl)-benzenesulfonamides as potent carbonic anhydrase inhibitors》, the research content is summarized as follows. Human carbonic anhydrases (hCA) I and II are targets for agents treating acute altitude sickness. Twenty-one 4-(1,3,4-oxadiazol-2-yl) benzenesulfonamides were synthesized and screened against these two isoforms. 4-(5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide , 4-(5-(2,3-dichlorophenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, 4-(5-(4-(dimethylamino) phenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, 4-(5-(naphthalen-2-yl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide were more potent against both hCA I and II than clin. drug AAZ. In particular, the value of compound 4-(5-(2,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide with hCA I (18.08 nM) was over 84-fold more than of AAZ with hCA I. The data of docking simulations were also in accord with the tendency of inhibitive activities. Furthermore, methanesulfonate of 4-(5-(4-(dimethylamino) phenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, showed better anti-hypoxia activity than AAZ in vivo, making it interesting lead compound

SDS of cas: 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Category: pyridine-derivatives.

Yang, Qing;Yan, Xiao-Tong;Feng, Cheng-Tao;Chen, De-Xiang;Yan, Zhong-Zhong;Xu, Kun research published 《 Tandem Strecker/C(sp³)-H amination reactions for the construction of cyanide-functionalized imidazo[1,5-a]pyridines with NH₄SCN as a cyanating agent》, the research content is summarized as follows. An I₂O₅ promoted tandem Strecker/C(sp³)-H amination reaction of pyridine-2-carboxaldehydes, benzylamines and NH₄SCN was reported. This multicomponent reaction that allowed the single-step construction of biol. important cyano-functionalized imidazo[1,5-a]pyridines with mol. diversity was realized for the first time. Moreover, the use of safe and easy-to-handle NH₄SCN as a surrogate cyanating agent made this protocol appealing for potential applications.

Category: pyridine-derivatives, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Quality Control of 31181-90-5.

Zha, Gao-Feng;Fang, Wan-Yin;Leng, Jing;Qin, Hua-Li research published 《 A Simple, Mild and General Oxidation of Alcohols to Aldehydes or Ketones by SO₂F₂/K₂CO₃ Using DMSO as Solvent and Oxidant》, the research content is summarized as follows. A practical, general and mild oxidation of primary and secondary alcs. to carbonyl compounds proceeded in yields of up to 99% using SO₂F₂ as electrophile in DMSO as both the oxidant and the solvent at ambient temperature No moisture- and oxygen-free conditions were required. Stoichiometric amount of inexpensive K₂CO₃, which generated easy to sep. byproducts, was used as the base. Thus, 5-gm scale runs proceeded in nearly quant. yields by a simple filtration as the work-up. The use of a polar solvent such as DMSO, which usually promoted competing Pummerer rearrangement, was also noteworthy. This protocol was compatible with a variety of common N-, O- and S-functional groups on (hetero)arene, alkene and alkyne substrates. The protocol was applied (99% yield) to a formal synthesis of the important cholesterol-lowering drug Rosuvastatin.

Quality Control of 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. COA of Formula: C6H4BrNO.

Zhang, Bidong;Kurpiewska, Katarzyna;Doemling, Alexander research published 《 Highly Stereoselective Ugi/Pictet-Spengler Sequence》, the research content is summarized as follows. Discovering novel synthetic routes for rigid nitrogen-containing polyheterocycles using sustainable, atom-economical, and efficient (= short) synthetic pathways is of high interest in organic chem. Here, authors describe an operationally simple and short synthesis of the privileged scaffold dihydropyrrolo[1,2-a]pyrazine-dione from readily accessible starting materials. The alkaloid-type polycyclic scaffold with potential bioactivity was achieved by a multicomponent reaction (MCR)-based protocol via a Ugi four-component reaction and Pictet-Spengler sequence under different conditions, yielding a diverse library of products.

COA of Formula: C6H4BrNO, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Reference of 31181-90-5.

Wu, Yachuang;Ding, Xiudong;Yang, Yifeng;Li, Yingxiu;Qi, Yinliang;Hu, Feng;Qin, Mingze;Liu, Yajing;Sun, Lu;Zhao, Yanfang research published 《 Optimization of biaryloxazolidinone as promising antibacterial agents against antibiotic-susceptible and antibiotic-resistant gram-positive bacteria》, the research content is summarized as follows. Herein, novel biaryloxazolidinone analogs I [X = O, S, NMe, etc.; Y = N, CH, CHOH, etc.; Z = N, CH] were designed and synthesized to improve the chem. and metabolic stability. Compounds I [X = S, NMe, SO₂; Y = N, CHOH; Z = CH] showed significant antibacterial activity against the tested Gram-pos. bacteria as compared to radezolid and linezolid. Further studies indicated that most of them exhibited improved water solubility and chem. stability. Compound I [X = SO₂; Y = N; Z = CH] had MIC values of 0.125-0.25 μg/mL against all tested Gram-pos. bacteria, and showed excellent antibacterial activity against clin. isolates of antibiotic-susceptible and antibiotic-resistant bacteria. Moreover, it was stable in human liver microsome. From a safety viewpoint, it showed non-cytotoxic activity against hepatic cell and exhibited lower inhibitory activity against human MAO-A compared to linezolid. The potent antibacterial activity and all these improved drug-likeness properties and safety profile suggested that compound I [X = SO₂; Y = N; Z = CH] might be a promising drug candidate for further investigation.

31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., Reference of 31181-90-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. COA of Formula: C6H4BrNO.

Xia, Wu;Ren, Ying-Yi;Liu, Jing;Deng, Bo-Yi;Wang, Feng research published 《 Non-synergistic photocatalysis of CO₂-to-CO conversion by a binuclear complex of rigidly linking two cobalt catalytic centers》, the research content is summarized as follows. A novel binuclear cobalt complex C1 of rigidly linking two [Co(TPA)Cl]Cl moieties at meta positions of a benzene was synthesized and characterized as a catalyst for homogeneous photocatalytic CO₂ reduction Different from state-of-the-art binuclear catalyst catalyzing CO2 reduction with a synergistic catalysis mechanism, C1 catalyzes CO₂-to-CO conversion independently at each cobalt catalytic center. At an optimal condition, system of C1 produced CO with a TON of 721 (based on C1, corrsoponding to TON 360 per cobalt center) and a high selectivity of 91.5%. Electrochem. and steady state spectroscopy studies revealed that a Co^ICo^I species, generated via successive photoinduced electron transfer from excited photosensitizer to C1, is the active species of CO₂ conversion. No synergistic effect of two cobalt centers exists for CO₂ reduction because of larger Co-Co distance and rigid structure of C1.

31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., COA of Formula: C6H4BrNO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Quality Control of 31181-90-5.

Xue, Si-tu;Wang, Ya-li;Han, Xiao-wan;Yi, Hong;Jiang, Wei;Si, Shu-yi;Guo, Hui-fang;Li, Zhuo-rong research published 《 Novel cathepsin K inhibitors block osteoclasts in vitro and increase spinal bone density in zebrafish》, the research content is summarized as follows. Cathepsin K (Cat K) is a predominant cysteine protease and highly potent collagenase expressed in osteoclasts. Cat K inhibitors are anti-resorptive agents to treat osteoporosis. A novel scaffold of cathepsin K inhibitors, exemplified by lead compound 1x, was used as the template for designing and synthesizing a total of 61 derivatives that have not been reported before. An exploratory structure-activity relationship anal. identified the potent Cat K inhibitor A22, which displayed an IC₅₀ value of 0.44μM against Cat K. A22 was very specific for Cat K and caused a significantly higher in vitro inhibition of the enzyme as compared to that of lead compound 1x. A surface plasmon resonance anal. confirmed in vitro binding of A22 to Cat K. Mol. docking studies indicated several favorable interaction sites for A22 within the active pocket of Cat K. Furthermore, A22 also blocked active osteoclasts in vitro and increased spinal bone d. in zebrafish, in which it showed an activity that was higher than that of the marketed therapeutic bone metabolizer etidronate disodium. A22 represents a very promising lead compound for the development of novel antiresorptive agents functioning as orthosteric inhibitors of Cat K.

Quality Control of 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Application of C6H4BrNO.

Yan, Qing;Qiao, Zhu;Zhao, Weizhen;Ren, Jun;Wang, Yun;Yang, Wanmei;Wang, Sheng research published 《 All-visible-light triggered solid-state dual-color fluorescence switching of phenanthroimidazole-based bisthienylethene》, the research content is summarized as follows. All-visible-light controlled fluorescence switching is more promising for bioimaging. Constructing dual-color fluorescent bisthienylethene (BTE) systems are quite challenging. Here, all-visible-light triggered dual-color fluorescence switching was achieved in a color-specific switching manner in a solid-state by associating the photochromic BTE core with a blue emissive phenanthroimidazole (PI) unit. Unique emission behavior caused by J-aggregation of the coplanar PI unit was crucial, which suggested a novel strategy for constructing dual-color fluorescent photoswitching. Moreover, a ‘turn-off’ fluorescence photoswitching was demonstrated in solution and PMMA films owing to the energy transfer from the PI moiety to a ring-closed isomer of the BTE moiety. Remarkably, an all-visible-light patterning application for information storage medium was developed with these compounds BTE-P1 was successfully utilized in cellular imaging for efficient fluorescence switching.

31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., Application of C6H4BrNO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. SDS of cas: 31181-90-5.

Wang, Yan-Yan;Xu, Fang-Zhou;Zhu, Yun-Ying;Song, Baoan;Luo, Dexia;Yu, Gang;Chen, Shunhong;Xue, Wei;Wu, Jian research published 《 Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents》, the research content is summarized as follows. A series of pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety were synthesized, characterized, and evaluated for their activity against tobacco mosaic virus (TMV). Biol. assays indicated that several of the derivatives exhibited significant activity against TMV. In particularly, compounds (E)-1,3,6-Trimethyl-5-(((5-methylthiophen-2-yl)methylene)amino)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one and 5aa displayed excellent inactivating activity against TMV, with half maximal effective concentration (EC₅₀) values of 70.3 and 53.65μg/mL, resp., which were much better than that of ribavirin (150.45μg/mL), and 5aa was superior to ningnanmycin (EC₅₀=55.35μg/mL). Interactions of compounds (E)-1,3,6-Trimethyl-5-(((5-methylthiophen-2-yl)methylene)amino)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one and (E)-5-(((6-Bromopyridin-3-yl)methylene)amino)-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one with TMV coat protein (TMV-CP) were studied using microscale thermophoresis and mol. docking. Compounds (E)-1,3,6-Trimethyl-5-(((5-methylthiophen-2-yl)methylene)amino)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one and (E)-5-(((6-Bromopyridin-3-yl)methylene)amino)-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one displayed strong binding capability to TMV-CP with dissociation constant (K_d) values of 22.6 and 9.8μM, resp. Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base may be potential antiviral agents.

31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., SDS of cas: 31181-90-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem