Category: 34160-40-2

Related Products of 34160-40-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 34160-40-2, name is 6-Bromo-2-pyridinecarboxaldehyde. This compound has unique chemical properties. The synthetic route is as follows.

192 mg (1 mmol) of 6-bromo-2-pyridinecarboxaldehyde and 152 mg (1.2 mmol) of phenylboronic acid were dissolved in 10 mL of tetrahydrofuran (THF). 1 ml (1 mmol) of Na2CO3 in aqueous solution (1M) and 8 mg (0.7%) of Pd(PPh3)4 were added. The reaction mixture was heated during 45mn, at a temperature of 130C in a micro-wave reactor. The solution was filtered on paper, 10 ml of AcOEt were added and the organic phase was successively washed with NaHCO3, with H2O and with an aqueous solution of NaCl. The organic phase was dried over MgSO4, filtered and evaporated to dryness. After a chromatography on silica gel (Pentane/Et2O, 1/1), 136 mg of aldehyde A were obtained as colourless oil with a yield of 74%. [Show Image] 1H NMR (300 MHz, CDCl3) delta (ppm): 10.17 (s, 1 H), 8.11 (d, J=6Hz, 2H), 7.89 (m, 3H), 7.49 (m, 3H) 13C{1H} NMR (75 MHz, CDCl3) delta (ppm): 114.5, 119.2, 121.8, 123.7, 124.4, 132.5, 132.8, 147.5, 188.7.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 34160-40-2, 6-Bromo-2-pyridinecarboxaldehyde.

Reference:
Patent; TOTAL PETROCHEMICALS RESEARCH FELUY; EP1849791; (2007); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 34160-40-2, name is 6-Bromo-2-pyridinecarboxaldehyde. This compound has unique chemical properties. The synthetic route is as follows. name: 6-Bromo-2-pyridinecarboxaldehyde

Step 1: Synthesis of 2-bromo-6-(difluoromethyl)pyridine (0396) 3.81 g (23.6 mmol) of (diethylamino)sulfur trifluoride were added with ice cooling to a mixed solution of 2.00 g (10.8 mmol) of 6-bromopicolinaldehyde and 40 ml methylene chloride. After completion of the addition, said reaction mixture liquid was stirred for 2 hours with ice cooling. After completion of the stirring, the reaction was stopped by addition of 30 ml of saturated aqueous sodium hydrogen carbonate solution, and said reaction liquid was extracted with methylene chloride (2×30 ml). The organic layer obtained was washed with water, then dried with anhydrous sodium sulfate, and the solvent distilled off under reduced pressure. The residue obtained was purified by silica gel chromatography (n-hexane:ethyl acetate=10:0 to 8:2), and 1.87 g of the desired compound were obtained as a white solid. (0397) 1H-NMR (CDCl3, Me4Si, 300 MHz): delta 7.73-7.58 (m, 3H), 6.58 (t, 1H, J=56 Hz).

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 34160-40-2, 6-Bromo-2-pyridinecarboxaldehyde.

Reference:
Patent; SYNGENTA PARTICIPATIONS AG; NAKAYA, Yoshihiko; MASUZAWA, Yoshihide; FURUHASHI, Takamasa; MIYAKADO, Yuuki; HOTTA, Hiroyasu; INABA, Masamitsu; (76 pag.)US2016/221998; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem