Category: 3469-63-4

Schmidt, Michael A. published the artcileEffect of Terminal Alkylation of Aryl and Heteroaryl Hydrazines in the Fischer Indole Synthesis, Computed Properties of 3469-63-4, the main research area is Fischer indole synthesis; hydrazine ketone alkylation amidation cross coupling.

The effect of alkylation on the terminal position of aryl and heteroaryl hydrazines in the Fischer indole synthesis was examined Compared to their unalkylated counterparts, reactions using alkylated s provided indole products with higher yields and faster rates. The reactions can be conducted at lower temperatures and are compatible with acid-sensitive functionality. The terminally alkylated hydrazines were readily prepared by a new two-step sequence and held as stable hydrazinium salts. The mild formation of the salts along with the favorable Fischer indole reaction conditions highlights the potential of this approach in later-stage synthetic use.

Journal of Organic Chemistry published new progress about Alkylation. 3469-63-4 belongs to class pyridine-derivatives, name is Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate, and the molecular formula is C11H12N2O3, Computed Properties of 3469-63-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Schmidt, Michael A. published the artcileEffect of Terminal Alkylation of Aryl and Heteroaryl Hydrazines in the Fischer Indole Synthesis, Computed Properties of 3469-63-4, the main research area is Fischer indole synthesis; hydrazine ketone alkylation amidation cross coupling.

The effect of alkylation on the terminal position of aryl and heteroaryl hydrazines in the Fischer indole synthesis was examined Compared to their unalkylated counterparts, reactions using alkylated s provided indole products with higher yields and faster rates. The reactions can be conducted at lower temperatures and are compatible with acid-sensitive functionality. The terminally alkylated hydrazines were readily prepared by a new two-step sequence and held as stable hydrazinium salts. The mild formation of the salts along with the favorable Fischer indole reaction conditions highlights the potential of this approach in later-stage synthetic use.

Journal of Organic Chemistry published new progress about Alkylation. 3469-63-4 belongs to class pyridine-derivatives, name is Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate, and the molecular formula is C11H12N2O3, Computed Properties of 3469-63-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Parrino, Barbara published the artcileSynthesis of the new ring system bispyrido[4′,3′:4,5]pyrrolo[1,2-a:1′,2′-d]pyrazine and its deaza analogue, Category: pyridine-derivatives, the main research area is pyrrolopyridinecarboxylic acid preparation; bispyridopyrrolopyrazine dione preparation antineoplastic mol docking; pyridopyrrolopyrazino indole dione antineoplastic mol docking.

A series of bispyridopyrrolopyrazine diones I [R1 = R4 = H, Cl, OMe; R2 = R3 = H, OMe] and their deaza analogs pyridopyrrolopyrazinoindole diones II [R1 = R2 = H, Cl, OMe] was synthesized and evaluated for their antineoplastic activities and mol. docking studies. Among the synthesized compounds I [R1 = R2 = R4 = H; R3 = OMe] and II [R1 = R2 = H; R1 = OMe, R2 = H; R1 = H, R2 = OMe] exhibited modest activity against MCF7 (a breast cancer cell line) and/or UO-31 (a renal cancer cell line).

Molecules published new progress about Antitumor agents. 3469-63-4 belongs to class pyridine-derivatives, name is Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate, and the molecular formula is C11H12N2O3, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Frydman, Benjamin published the artcilePyrroles from azaindoles. Synthesis of porphobilinogen and related pyrroles, Recommanded Product: Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate, the main research area is porphobilinogen pyrrole; pyrrole porphobilinogen.

A new method for the synthesis of 2-aminomethyl-3-pyrroleacetic acids is described. The condensation of 2-methoxy- and 2-benzyloxy-4-methyl-5-nitropyridine with diethyl oxalate afforded the corresponding Et o-nitropyri-dinepyruvates, which on hydrogenation were transformed into the substituted Et 6-azaindole-2-carboxylates. Cleavage of the ethers and hydrogenation of the resulting pyrrolopyridones yielded the corresponding carboxypyrrole lactams which on decarboxylation and hydrolysis gave the 2-aminomethyl-3-pyrroleacetic acids. Substitution at the C-3 position of the 6-azaindole with a propionic acid and acetic asid side chain and repetition of the above sequence gave porphobilinogen and 2-aminomethyl-3,4-pyrrolediacetic acid.

Journal of the American Chemical Society published new progress about porphobilinogen pyrrole; pyrrole porphobilinogen. 3469-63-4 belongs to class pyridine-derivatives, name is Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate, and the molecular formula is C11H12N2O3, Recommanded Product: Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rahimpour, Parivash published the artcileRelationship Between the Parenting Styles and Students’ Educational Performance Among Iranian Girl High School Students, A Cross- Sectional Study., Quality Control of 3469-63-4, the main research area is Authoritarian parenting style; Authoritative parenting styles; Permissive parenting style.

INTRODUCTION: Parenting styles are effective in the educational performance of their child. The present study aimed to investigate the relationship between the parenting styles and students’ educational performance among Iranian girl high school students. MATERIALS AND METHODS: In a cross-sectional survey, female students in high schools of Ilam (Iran) evaluated during the academic year 2014-15. Multistage cluster random sampling was used to select the participants. Data were collected by two demographic and Baumrind’s parenting styles questionnaire. The Cronbach’s alpha coefficient was measured as an index of internal identicalness of the questionnaire to verify its reliability. RESULTS: A total 400 students were studied. The Mean±SD of the students’ age were 14±1.08. The students’ school grades were the first year of high school to pre-university course. The Mean±SD of parenting styles were 35.37±5.8, 34.69±6.34 and 19.17±6.64 for permissive parenting style, authoritarian parenting style and authoritative parenting styles, respectively. There was a significant relationship between the score of permissive parenting style (p= 0.001, r= 0.151), authoritarian parenting style (p= 0.001, r= 0.343) and authoritative parenting style (p=0. 001, r= 0.261) with the students’ average score for studying. CONCLUSION: The results of this study demonstrate that parental influence plays an important role in students’ educational performance.

Journal of clinical and diagnostic research : JCDR published new progress about Authoritarian parenting style; Authoritative parenting styles; Permissive parenting style. 3469-63-4 belongs to class pyridine-derivatives, name is Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate, and the molecular formula is C11H12N2O3, Quality Control of 3469-63-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem