Category: 350-03-8

Zhang, Tian-Hua; Bai, Chao; Hu, Huai-Ming; Zhang, Jun-Lin; Li, Xuan-Yue; Wang, Xiaofang; Wang, Bo-Zhou published the artcile< Cadmium(II) and cobalt(II) coordination compounds based on a benzenesulfonic terpyridine ligand: Syntheses, structures, luminescent sensing and magnetic properties>, Recommanded Product: 1-(Pyridin-3-yl)ethanone, the main research area is cadmium cobalt terpyridinylbenzenesulfonate complex preparation luminescent probe; magnetic susceptibility cadmium cobalt terpyridinylbenzenesulfonate complex; crystal structure cadmium cobalt terpyridinylbenzenesulfonate complex.

Five coordination compounds based on a new ligand with terpyridyl and benzenesulfonyl groups, [Cd(STP)2]n (1), [Cd(STP)Cl(H2O)]n·2nH2O (2), [Cd(STP)Br(H2O)]n·2nH2O (3), [Co(STP)2]n (4), [Co(STP)2(H2O)4]·H2O (5) (HSTP = 2-(3,2′:6′,3”-terpyridin-4′-yl)benzenesulfonic acid) were synthesized and characterized by FT-IR, elemental anal., and single crystal X-ray diffraction. Compounds 1 and 4 exhibit a (3,6)-connected 2D layer structure with 3,6L40 topol. network and point symbol of {3·62}{66·96·123}. Compounds 2 and 3 display a 3D topol. network with fsc-3 network and point symbol of {4·6·8}{4·62·83}. Compound 5 shows a discrete mononuclear structure. The structural diversity of compounds 1-5 indicates that counter anions, pH values and coordination modes of STP- anions are significant influence on the final structures. Investigation of luminescent property indicates that compound 3 can be used as a recycled probe with high sensitivity and selectivity to detect acetone and Cr2O72- anion. The KSV of compound 3 for acetone and Cr2O72- anion are 1.295 x 104 M-1 and 5.79 x 102 M-1, resp. The PXRD and UV-Vis spectra indicates that the quenching mechanism of compound 3 toward Cr2O72- anion can be attributed to light competitive absorption. Addnl., magnetic property of compounds 4 and 5 was investigated. The difference of magnetic interactions between compounds 4 and 5 may be caused by different coordination fields.

Journal of Solid State Chemistry published new progress about Crystal structure. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Recommanded Product: 1-(Pyridin-3-yl)ethanone.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Esch, Patrick; Heiles, Sven published the artcile< Investigating C-C positions and hydroxylation sites in lipids using Paterno-Buechi functionalization mass spectrometry>, HPLC of Formula: 350-03-8, the main research area is double carbon bond lipid oxidation Paterno Buechi functionalization MS; Sacha inchi oil triglyceride oxidation Paterno Buechi functionalization MS.

Lipid oxidation plays a major role in biochem. processes and nutrition. Structural changes during oxidation can lead to alterations of lipid functions. Rancidification and production of secondary lipid messengers are well-known examples for the impact of oxidation on lipid function. Especially lipids with a high degree of unsaturation are prone to oxidize. In order to investigate structural changes of lipids upon oxidation, we here introduce a photochem. Paterno-Buechi functionalization workflow and subsequent mass spectrometric anal. for anal. of unsaturated, oxidized lipids. Results for hydroxylated fatty acids and triglycerides containing isolated and conjugated C-C bonds will be presented making use of 3-acetylpyridine as a photochem. active compound Photochem. derivatization is performed in nano-electrospray emitter tips in 30 s resulting in the formation of oxetanes without inducing light-triggered oxidation of analytes. Collisional-activation of photoproducts facilitates selective cleavage of oxetane moieties. Resulting fragment ions not only allow the determination of C-C bond locations for isolated and conjugated C-C bonds but also restrict the site of oxidation By registering the mass shift in some fragment ions of +15.99 Da due to hydroxylation, the oxidized sections of lipids can be identified. In order to demonstrate its anal. robustness, the method is applied to determine the structural impact of non-selective ambient oxidation on fatty acids, triglycerides and complex triglyceride mixtures obtained from Sacha inchi oil.

Analyst (Cambridge, United Kingdom) published new progress about C-C bond, double. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, HPLC of Formula: 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Steyer, Daniel J.; Kennedy, Robert T. published the artcile< High-Throughput Nanoelectrospray Ionization-Mass Spectrometry Analysis of Microfluidic Droplet Samples>, Formula: C7H7NO, the main research area is high throughput nanoelectrospray mass spectrometry droplet microfluidics.

Droplet microfluidics enables high-throughput manipulation of fL-μL volume samples. Methods implemented for the chem. anal. of microfluidic droplets have been limited in scope, leaving some applications of droplet microfluidics difficult to perform or out of reach entirely. Nanoelectrospray ionization-mass spectrometry (nESI-MS) is an attractive approach for droplet anal., because it allows rapid, label-free, information-rich anal. with high mass sensitivity and resistance to matrix effects. Previous proof-of-concept systems for the nESI-MS anal. of droplets have been limited by the microfluidics used so that stable, long-term operation needed for high-throughput applications has not been demonstrated. The authors describe a platform for the stable anal. of microfluidic droplet samples by nESI-MS. Continuous infusion of droplets to an nESI emitter was demonstrated for as long as 2.5 h, corresponding to anal. of over 20 000 samples. Stable signal was observed for droplets as small as 65 pL and for throughputs as high as 10 droplets/s. A linear-concentration-based response and sample-to-sample carryover of <3% were also shown. The system is demonstrated for measuring products of in-droplet enzymic reactions. Analytical Chemistry (Washington, DC, United States) published new progress about Droplet microfluidics. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bori, Jugal; Mahata, Satyajit; Manivannan, Vadivelu published the artcile< A new route for the synthesis of 2,4-bis(2-pyridyl)-6-(pyridyl)pyrimidines: Synthesis and characterization of Co(II), Ni(II) complexes of 2,4,6-tris(2-pyridyl)pyrimidine>, Application In Synthesis of 350-03-8, the main research area is cobalt nickel pyridyl pyrimidine complex preparation crystal structure DFT; EPR spectra cobalt nickel pyridyl pyrimidine complex.

Using 2-acetylpyridine, sodium hydroxide and 2-cyanopyridine, 2,4,6-tris(2-pyridyl)pyrimidine (L1) was synthesized in good yield. Similarly, 2,4-bis(2-pyridyl)-6-(3-pyridyl)pyrimidine (L2) and 2,4-bis(2-pyridyl)-6-(4-pyridyl)pyrimidine (L3) were also synthesized by using resp. acetylpyridine. 2-Acetylpyridine reacted with sodium hydroxide to produce 2-oxo-2-(2-pyridyl)-1-ethanide, which behaves as a nucleophile towards 2-cyanopyridine. All three pyrimidines are potential multidentate ligand and by using L1 complexes of composition [Ni(L1)(H2O)3](NO3)2·4H2O (1), [Ni(L1)2](NO3)2·2H2O (2) and [Co(L1)2](NO3)2·1.5H2O (3) were isolated and structurally characterized. In 1-3, L1 behaves as a tridentate pincer type ligand, DFT calculations performed on L1-L3 indicate that energy difference between HOMO and LUMO is 4.544, 4.643 and 4.533 eV, resp.

Inorganica Chimica Acta published new progress about Crystal structure. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Application In Synthesis of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Jiacheng; Siang Tan, Suan; Kyne, Sara Helen; Chan, Philip Wai Hong published the artcile< Minisci-Type Alkylation of N-Heteroarenes by N-(Acyloxy)phthalimide Esters Mediated by a Hantzsch Ester and Blue LED Light>, Category: pyridine-derivatives, the main research area is alkylated quinoline preparation; quinoline acyloxy phthalimide ester Minisci type alkylation HE mediated; isoquinoline alkylated preparation; acyloxy phthalimide ester isoquinoline Minisci type alkylation HE mediated; pyridine alkylated preparation; phthalimide ester acyloxy pyridine Minisci type alkylation HE mediated.

A synthetic method that enabled the Hantzsch ester (HE)-mediated Minisci-type C2-alkylation of quinolines, isoquinolines and pyridines by N-(acyloxy)phthalimide esters (NHPI) to afford alkylated N-heterocyclic products, e.g., I, under blue LED (light emitting diode) light (456 nm) was described. Achieved under mild reaction conditions at room temperature, the metal-free synthetic protocol was shown to be applicable to primary, secondary and tertiary NHPIs to give the alkylated N-heterocyclic products in yields of 21-99%. On introducing a chiral phosphoric acid, an asym. version of the reaction was also realized and provided product enantiomeric excess (ee) values of 53-99%.

Advanced Synthesis & Catalysis published new progress about Alkylation. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chinna Ayya, Swamy .P.; Varenikov, Andrii; de Ruiter, Graham published the artcile< Chiral Imidazo[1,5-a]pyridine-Oxazolines: A Versatile Family of NHC Ligands for the Highly Enantioselective Hydrosilylation of Ketones>, Recommanded Product: 1-(Pyridin-3-yl)ethanone, the main research area is chiral imidazopyridineoxazoline bidentate ligand preparation cyclometalation rhodium complex; rhodium imidazopyridineoxazoline bidentate carbene complex preparation catalyst hydrosilylation ketone; alc chiral enantioselective preparation.

Herein the authors report the synthesis and application of a versatile class of N-heterocyclic carbene ligands based on an imidazo[1,5-a]pyridine-3-ylidine backbone that is fused to a chiral oxazoline auxiliary. The key step in the synthesis of these ligands involves the installation of the oxazoline functionality via a microwave-assisted condensation of a cyano-azolium salt with a wide variety of 2-amino alcs. The resulting chiral bidentate NHC-oxazoline ligands form stable complexes with Rh(I) that are efficient catalysts for the enantioselective hydrosilylation of structurally diverse ketones. The corresponding secondary alcs. are isolated in good yields (typically >90%) with good to excellent enantioselectivities (80-95% ee). The reported hydrosilylation occurs at ambient temperatures (40°), with excellent functional group tolerability. Even ketones bearing heterocyclic substituents (e.g., pyridine or thiophene) or complex organic architectures are hydrosilylated efficiently, which is discussed further.

Organometallics published new progress about Alcohols, chiral Role: SPN (Synthetic Preparation), PREP (Preparation). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Recommanded Product: 1-(Pyridin-3-yl)ethanone.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhou, Sen; Sun, Ze-Ying; Zhu, Kongying; Zhao, Wentao; Tang, Xiangyang; Guo, Minjie; Wang, Guangwei published the artcile< Metal-Free Difunctionalization of Pyridines: Selective Construction of N-CF2H and N-CHO Dihydropyridines>, Quality Control of 350-03-8, the main research area is pyridine nitroalkane bromodifluoroacetate regioselective nucleophilic addition; nitroalkyl difluoromethyl dihydropyridine preparation; nitromethylene difluoromethyl dihydropyridine preparation; formyl difluoromethyl dihydropyridine preparation.

A novel nucleophilic addition of N-difluoromethylpyridinium salts with nitroalkanes to synthesize N-CF2H-dihydropyridines and N-CHO-dihydropyridines in a highly efficient and regioselective pathway was reported. This protocol exhibited good functional group tolerance and good to excellent yields.

Organic Letters published new progress about Alkanes, nitro Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Quality Control of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Shvydkiy, Nikita V.; Vyhivskyi, Oleksandr; Nelyubina, Yulia V.; Perekalin, Dmitry S. published the artcile< Design of Manganese Phenol Pi-complexes as Shvo-type Catalysts for Transfer Hydrogenation of Ketones>, Formula: C7H7NO, the main research area is manganese phenol pi complex preparation; secondary alc preparation; ketone transfer hydrogenation manganese complex catalyst.

The ability of the manganese pi-complexes to act as Shvo-type catalysts for transfer hydrogenation of ketones to afford secondary alcs. RCH(OH)(R1) [R = Ph, 3-pyridyl, 1-naphthyl, etc.; R1 = Me, n-Pr, Ph, etc.] was explored. DFT calculations suggested that the transfer of hydrogen atoms from the hypothetical intermediate [(C6Me3H2OH)Mn(CO)2H] to acetone had low activation barrier of 10.9 kcal mol-1. Exptl. a number of ketones with various functional groups were successfully reduced in isopropanol in the presence of the complex [(C6Me3H2OH)Mn(CO)3]BF4 (1 mol %) and tBuOK (75 mol %). However, further investigation revealed that the reduction was mainly promoted by base rather than the manganese complex.

ChemCatChem published new progress about Ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mujahed, Shrouq; Hey-Hawkins, Evamarie; Gelman, Dmitri published the artcile< A High-Valent Ru-PCP Pincer Catalyst for Hydrogenation of Carbonyl and Carboxyl Compounds under Molecular Hydrogen>, HPLC of Formula: 350-03-8, the main research area is high valent ruthenium phosphorus carbon PCP pincer catalyst hydrogenation; carbonyl carboxyl nitrile compound hydrogenation catalyst preparation; crystal mol structure ruthenium phosphorus carbon PCP pincer complex; cooperative catalysis; esters; high-valent ruthenium; hydrogenation; pincer complexes.

Low-valent metals traditionally dominate the domain of catalytic hydrogenation. However, metal-ligand cooperating (MLC) catalytic systems, operating through heterolytic H-H bond splitting by a Lewis acidic metal and a basic ligand site, do not require an electron-rich metal. On the contrary, high-valent metals that induce weaker back donation facilitate heterolytic bond activation. Here authors report, for the first time, the efficient hydrogenation of carbonyl and carboxyl compounds under mol. hydrogen catalyzed by a structurally well-defined RuIV catalyst bearing a bifunctional PCP pincer ligand. The catalyst exhibits reactivity toward mol. hydrogen superior to that of the low-valent analog and allows hydrogen activation even at room temperature

Chemistry – A European Journal published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, HPLC of Formula: 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zeng, Haisu; Wu, Jing; Li, Sihan; Hui, Christina; Ta, Anita; Cheng, Shu-Yuan; Zheng, Shengping; Zhang, Guoqi published the artcile< Copper(II)-Catalyzed Selective Hydroboration of Ketones and Aldehydes>, Application In Synthesis of 350-03-8, the main research area is divalent copper catalyzed chemoselective hydroboration ketone aldehyde; nonanuclear copper complex one pot self assembly preparation.

A novel nonanuclear copper(II) complex obtained by a facile one-pot self-assembly was found to catalyze the hydroboration of ketones and aldehydes with the absence of an activator under mild, solvent-free conditions. The catalyst is air- and moisture-stable, displaying high efficiency (1980 h-1 turnover frequency, TOF) and chemoselectivity on aldehydes over ketones and ketones over imines. This represents a rare example of divalent copper catalyst for the hydroboration of carbonyls.

Organic Letters published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Application In Synthesis of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem