Category: 350-03-8

Aversa-Fleener, Cara R.; Chang, Daniel K.; Liberman-Martin, Allegra L. published the artcile< Carbodiphosphorane-Catalyzed Hydroboration of Ketones and Imines>, Quality Control of 350-03-8, the main research area is carbodiphosphorane catalyzed hydroboration ketone imine aldehyde; pinacol boronate ester preparation.

The authors report the use of a cyclic carbodiphosphorane catalyst for ketone and imine hydroboration reactions. Ketone hydroboration reactions are particularly rapid, typically reaching completion within 15 min using a 1 mol % catalyst loading at 25°. To the authors’ knowledge, this represents the 1st use of a carbodiphosphorane as an organocatalyst. The carbodiphosphorane exhibited superior catalytic activity in comparison to other neutral C nucleophiles tested, including an N-heterocyclic carbene, an N-heterocyclic olefin, and P ylides.

Organometallics published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Quality Control of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hu, Chaopeng; Zhang, Jianying; Yang, Hao; Guo, Lulu; Cui, Chunming published the artcile< Synthesis of Cationic Silaamidinate Germylenes and Stannylenes and the Catalytic Application for Hydroboration of Pyridines>, HPLC of Formula: 350-03-8, the main research area is cationic silaamidinate germylene stannylene preparation catalyst hydroboration pyridine; crystal structure cationic silaamidinate germylene stannylene; mol structure cationic silaamidinate germylene stannylene; silaamidine deprotonation reaction germanium tin chloride.

The N-heterocyclic germylenes and stannylenes LSi(NAr)2EX (L = PhC(NtBu)2, Ar = 2,6-iPr2C6H3; E = Ge, Sn; X = Cl, CF3SO3, BPh4) supported by the bulky silaamidinate ligand [LSi(NAr)2]- were synthesized and fully characterized. The germylene triflate LSi(NAr)2GeOTf (3b) and dimeric borate [LSi(NAr)2Ge]2ClBPh4 (3a) enabled highly regio- and chemoselective catalytic hydroboration of pyridines and may represent the most active catalytic system for the transformation. DFT calculations disclosed that the cationic germylene [LSi(NAr)2Ge]+ with a low-lying LUMO energy initiated the catalytic process. In contrast, the analogous amidinate germylene triflates are almost inactive, indicating the silaamidinate ligand is essential for the stabilization of cationic species.

Inorganic Chemistry published new progress about Amidination. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, HPLC of Formula: 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Youssef, Heba; Sedykh, Alexander E.; Becker, Jonathan; Schafer, Thomas; Taydakov, Ilya V.; Li, Huanrong R.; Mueller-Buschbaum, Klaus published the artcile< Variable Luminescence and Chromaticity of Homoleptic Frameworks of the Lanthanides together with Pyridylpyrazolates>, Electric Literature of 350-03-8, the main research area is lanthanide pyridylpyrazolate coordination polymer homoleptic framework chromaticity luminescence; rare earth pyridylpyrazolate coordination polymer homoleptic framework chromaticity luminescence; N ligands; coordination polymers; homoleptic; lanthanides; luminescence.

Homoleptic, 3D coordination polymers of the formula 33∞[Ln(3-PyPz)3] and 3∞[Ln(4-PyPz)3], (3-PyPz)- = 3-(3-pyridyl)pyrazolate anion, (4-PyPz)- = 3-(4-pyridyl)pyrazolate anion, both C8H6N3-, Ln = Sm, Eu, Gd, Tb, Dy, were obtained as highly luminescent frameworks by reaction of the lanthanide metals (Ln) with the aromatic heterocyclic amine ligands 3-PyPzH and 4-PyPzH. The compounds form 2 isotypic series of 3D coordination polymers and exhibit fair thermal stability up to 360°. The luminescence properties of all 10 compounds were determined in the solid state, with an antenna effect through ligand-metal energy transfer leading to high efficiency of the luminescence displayed by good quantum yields of up to 74%. The emission is mainly based on ion-specific lanthanide-dependent intra 4f-4f transitions for Tb3+: green, Dy3+: yellow, Sm3+: orange-red, Eu3+: red. For the Gd3+-containing compounds, the yellow emission of ligand triplet-based phosphorescence is observed at room temperature and 77 K. Codoping of the Gd-containing frameworks with Eu3+ and Tb3+ allow further shifting of the chromaticity towards white light emission.

Chemistry – A European Journal published new progress about Color. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Electric Literature of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Matsa, Ramkishore; Makam, Parameshwar; Sethi, Guneswar; Thottasseri, Ahammed Ameen; Kizhakkandiyil, Aswani Raj; Ramadas, Krishna; Mariappan, Vignesh; Pillai, Agieshkumar Balakrishna; Kannan, Tharanikkarasu published the artcile< Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies>, Quality Control of 350-03-8, the main research area is hydrazinyl thiazole pyridinyl preparation docking antitubercular cytotoxicity lipophilicity.

An array of pyridine appended 2-hydrazinylthiazole derivatives I (R1 = Me, Ph, 1-naphthyl, 3-pyridyl, etc.; R2 = H, Me) has been synthesized to discover novel chemotherapeutic agents for Mycobacterium tuberculosis (Mtb). The drug-likeness of pyridine appended 2-hydrazinylthiazole derivatives I was validated using the Lipinski and Veber rules. The designed thiazole mols. have been synthesized through Hantzsch thiazole methodologies. The in vitro antimycobacterial studies have been conducted using Luciferase reporter phage (LRP) assay. Out of thirty derivatives, the compounds I (R1 = Ph, R2 = H, Me; R1 = 2-FC6H4, R2 = H; R1 = 4-FC6H4, R2 = Me) exhibited good antimycobacterial activity against Mtb, an H37Rv strain, with the min. inhibitory concentration in the range of 6.40-7.14μM. In addition, in vitro cytotoxicity of active mols. has been observed against Human Embryonic Kidney Cell lines (HEK293t) using MTT assay. The compounds I (R1 = Ph, 4-FC6H4; R2 = Me) are nontoxic and their cell viability is 87% and 96.71% resp. The in silico analyses of the pyridine appended 2-hydrazinylthiazole derivatives have been used to find the mode of binding of the active compounds with KasA protein of Mtb. The active compounds showed a strong binding score (-5.27 to -6.23 kcal mol-1).

RSC Advances published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Quality Control of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ho, Dang Binh; Gargaro, Samantha; Klake, Raphael K.; Sieber, Joshua D. published the artcile< Development of a Modified System to Provide Improved Diastereocontrol in the Linear-Selective Cu-Catalyzed Reductive Coupling of Ketones and Allenamides>, Formula: C7H7NO, the main research area is chiral gamma lactone preparation; ketone allenamide reductive coupling linear selective copper.

Chiral γ-lactones are prevalent organic architectures found in a large array of natural products. In this work, authors disclose the development of a modified catalytic system utilizing a com. available Cu-phosphite catalyst for the diastereoselective reductive coupling of chiral allenamides and ketones to afford chiral γ-lactone precursors in 80:20 to 99:1 dr.

Journal of Organic Chemistry published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent) (allenamides). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rani, S. Mahil; Brindha, J.; Reji, T. F. Abbs Fen published the artcile< Synthesis, computational studies and antioxidant activity of some 3-(2-alkylamino-4-aminothiazole-5-oyl)pyridines>, Name: 1-(Pyridin-3-yl)ethanone, the main research area is alkylamino aminothiazoloyl pyridine preparation antioxidant DFT HOMO LUMO.

A series of thiazoloylpyridine derivatives I (R = Et, n-Pr, i-Pr, n-Bu, allyl) has been synthesized and analyzed to confirm the structure of the product using IR, 1H and 13C NMR, mass spectra and anal. data. Optimized structural and electronic parameters of all the compounds I have been calculated by using B3LYP/ 6-31G basis set. The Mulliken charges of all atoms have been evaluated. All the synthesized compounds I have been examined for antioxidant activities. The antioxidant activity of 3-(2-alkylamino-4-aminothiazol -5-oyl)pyridines I have been analyzed using DPPH radical scavenging assay. The compounds I (R = Et, n-Pr) possess higher radical scavenging activity.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about Antioxidants. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Name: 1-(Pyridin-3-yl)ethanone.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhu, Hongmei; Wu, Shaohang; Yao, Jiaxu; Chen, Rui; Pan, Ming; Chen, Weitao; Zhou, Jing; Zhang, Wenjun; Wang, Tao; Chen, Wei published the artcile< An effective surface modification strategy with high reproducibility for simultaneously improving efficiency and stability of inverted MA-free perovskite solar cells>, Computed Properties of 350-03-8, the main research area is perovskite solar cell surface modification high reproducibility efficiency stability.

Perovskite solar cells (PSCs) have become the front-running photovoltaic technol. and have triggered enormous research interest worldwide owing to their ultra-high solar-to-elec. power conversion efficiency and low fabrication costs, but their poor intrinsic stability issues still constitute the main obstacles that hinder their rapid commercialization. Herein, we demonstrate that, by carefully designing the modifier’s mol. structure, a facile, highly reproducible and scalable surface modification strategy can effectively enhance both the stability and efficiency of inverted PSCs. The most efficient modifier (2-acetylpyridine) can not only passivate the surface traps of the perovskite film but also enhance its stability against moisture by forming a hydrophobic capping layer on top. Accordingly, the efficiency of the inverted PSC has been improved from 16.75% to 20.05% for the best-performing one, which is, to our knowledge, among the highest values for inverted MA-free PSCs. More encouragingly, the stability of the modified devices can also be largely enhanced: the devices retained 95%, 90%, and 91% of their initial efficiencies after storage in the dark in ambient air for 2000 h, 85°C thermal aging for 500 h in the dark, and light soaking at 45°C for 500 h, resp.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about Electric current-potential relationship. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Computed Properties of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chakraborty, Gargi; Sikari, Rina; Das, Siuli; Mondal, Rakesh; Sinha, Suman; Banerjee, Seemika; Paul, Nanda D. published the artcile< Dehydrogenative Synthesis of Quinolines, 2-Aminoquinolines, and Quinazolines Using Singlet Diradical Ni(II)-Catalysts>, Formula: C7H7NO, the main research area is quinoline biomimetic synthesis; aminoquinoline biomimetic synthesis; quinazoline biomimetic synthesis; nickel complex diamine singlet diradical oxidative condensation coupling catalyst.

Simple, straightforward, and atom economic methods for the synthesis of quinolines, 2-aminoquinolines, and quinazolines via biomimetic dehydrogenative condensation/coupling reactions, catalyzed by well-defined inexpensive and easy to prepare singlet diradical Ni(II)-catalysts featuring two antiferromagnetically coupled singlet diradical diamine type ligands are described. Various polysubstituted quinolines, 2-aminoquinolines, and quinazolines were synthesized in moderate to good yields from different low-cost and readily accessible starting materials. Several control experiments were carried out to get insight into the reaction mechanism which shows that the nickel and the coordinated diamine ligands participate in a synergistic way during the dehydrogenation of alcs.

Journal of Organic Chemistry published new progress about Acetonitriles Role: RCT (Reactant), RACT (Reactant or Reagent) (phenylacetonitriles). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Das, Jagadish; Vellakkaran, Mari; Banerjee, Debasis published the artcile< Nickel-Catalyzed Alkylation of Ketone Enolates: Synthesis of Monoselective Linear Ketones>, Product Details of C7H7NO, the main research area is ketone alc nickel monoselective alkylation catalyst; linear ketone preparation green chem.

Herein we have developed a Ni-catalyzed protocol for the synthesis of linear ketones. Aryl, alkyl, and heteroaryl ketones as well as alcs. yielded the monoselective ketones in up to 90% yield. The catalytic protocol was successfully applied in to a gram-scale synthesis. For a practical utility, applications of a steroid derivative, oleyl alc., and naproxen alc. were employed. Preliminary catalytic investigations involving the isolation of a Ni intermediate and defined Ni-H species as well as a series of deuterium-labeling experiments were performed.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Product Details of C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rawat, Manish; Rawat, Diwan S. published the artcile< Cu2O-Decorated Marigold Hollow Alumina Microsphere Nanoparticles as a Robust and Efficient Catalyst for the Synthesis of Isoquinolones>, Electric Literature of 350-03-8, the main research area is copper oxide decorated marigold hollow alumina microsphere catalyst preparation; isoquinolone green preparation.

A novel Cu2O-decorated marigold hollow alumina microsphere nanocatalytic system for the synthesis of isoquinolones I [R1 = H, 7-Me, 6-F; R2 = Ph, 4-ClC6H4, 2-thienyl, etc.] using 2-bromobenzonitriles and ketones under neat condition was reported. The prepared nanocatalyst was well characterized by SEM, high-resolution transmission electron microscopy, powder X-ray diffraction, energy-dispersive X-ray anal., XPS and Brunauer-Emmett-Teller techniques. The present method was facile and showed better green chem. metrics such as low E-factor, high reaction mass efficiency, and high turnover number and could be reused for five cycles without any loss in its catalytic activity.

ACS Sustainable Chemistry & Engineering published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Electric Literature of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem