Category: 366-18-7

Hooda, Anjli; Nehra, Kapeesha; Dalal, Anuj; Bhagwan, Shri; Gupta, Isha; Singh, Devender; Kumar, Sumit published the artcile< Luminescent Features of Ternary Europium Complexes: Photophysical and Optoelectronic Evaluation>, Name: 2,2′-Bipyridine, the main research area is ternary europium complex luminescence photophys optoelectronics; Cyclovoltammograms; Europium complexes; Fluorinated β-diketone; Thermal analysis.

Trivalent europium complexes exhibit good luminescent characteristics. A series of octacoordinated ternary europium complexes with fluorinated diketone and heteroaromatic auxiliary unit were synthesized. The synthesized europium complexes were characterized by elemental, thermal, electrochem. and spectroscopic analyses. Band gap values lie in range of semiconductors which confirm the conducting behavior of prepared complexes. Photoluminescence spectra were recorded in solid state and DMSO solvent. Emission spectral profiles have displayed most intense peak at ∼ 612 nm corresponding to hypersensitive 5D0 → 7F2 transition. Colorimetric parameters suggest red luminous nature of europium complexes. The luminescent heteroleptic europium complexes might be utilized as emissive materials for fabricating display.

Journal of Fluorescence published new progress about Absorption spectra. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Name: 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bubnov, Michael P.; Teplova, Irina A.; Cherkasova, Anna V.; Baranov, Evgenii V.; Fukin, Georgy K.; Romanenko, Galina V.; Bogomyakov, Artem S.; Starikov, Andrey G.; Cherkasov, Vladimir K.; Abakumov, Gleb A. published the artcile< Metal-ligand ferromagnetic exchange interactions in heteroligand bis-o-semiquinonato nickel complexes with 2,2'-dipyridine and 1,10-phenanthroline>, COA of Formula: C10H8N2, the main research area is nickel semiquinonate complex preparation ferromagnetic exchange; optimized mol structure nickel semiquinonate complex; crystal structure nickel semiquinonate complex.

Novel bis-o-semiquinonato nickel complexes (2,2′-bpy)Ni(3,6-DBSQ)2 (1) and (1,10-phen)Ni(3,6-DBSQ)2 (2) was synthesized (2,2′-bpy is 2,2′-dipyridine; 1,10-phen is 1,10-phenanthroline; 3,6-DBSQ is anion-radical of 3,6-tert-butyl-o-benzoquinone). Single crystal x-ray diffraction study indicated distorted octahedral environment of nickel atom in both complexes. Variable temperature magnetic susceptibility measurement detected predomination of ferromagnetic exchange interactions between high spin nickel ion and anion-radicals of o-semiquinones. DFT calculations are in a good agreement with exptl. structural and magnetic results.

Polyhedron published new progress about Crystal structure. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, COA of Formula: C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Avci, Davut; Alturk, Sumeyye; Sonmez, Fatih; Tamer, Omer; Basoglu, Adil; Atalay, Yusuf; Zengin Kurt, Belma; Dege, Necmi published the artcile< A novel series of mixed-ligand M(II) complexes containing 2,2′-bipyridyl as potent α-glucosidase inhibitor: synthesis, crystal structure, DFT calculations, and molecular docking>, Application of C10H8N2, the main research area is 2,2′-Bipyridyl and 6-methylpyridine-2-carboxylic acid; DFT/HSE06; Docking; XRD, FT-IR and UV–Vis; α-Glucosidase.

Diabetes mellitus (DM) is a common degenerative disease and characterized by high blood glucose levels. Since the effective antidiabetic treatments attempt to decrease blood glucose levels, keeping glucose under control is very important. Recent studies have demonstrated that α-glucosidase inhibitor improves postprandial hyperglycemia and then reduces the risk of developing type 2 diabetes in patients. Therefore, the design and synthesis of high affinity glucosidase inhibitors are of great importance. In this regard, novel series of mixed-ligand M(II) complexes containing 2,2′-bipyridyl {[Hg(6-mpa)2(bpy)(OAc)]·2H2O, (1), [Co(6-mpa)2(bpy)2], (2), [Cu(6-mpa)(bpy)(NO3)]·3H2O, (3), [Mn(6-mpa)(bpy)(H2O)2], (4), [Ni(6-mpa)(bpy)(H2O)2]·H2O, (5), [Fe(6-mpa)(bpy)(H2O)2]·2H2O, (6), [Fe(3-mpa)(bpy)(H2O)2]·H2O, (7)} were synthesized as potential α-glucosidase inhibitors. Their effects on α-glucosidase activity were evaluated. All synthesized complexes displayed α-glucosidase inhibitory activity with IC50 values ranging from 0.184 ± 0.015 to > 600 μM. The exptl. spectral analyses were carried out using FT-IR and UV-Vis spectroscopic techniques for these complexes characterized by XRD and LC-MS/MS. Moreover, the calculations at d. functional theory approximation were used to obtain optimal mol. geometries, vibrational wavenumbers, electronic spectral behaviors, and major contributions to the electronic transitions for the complexes 1-7. Finally, to display interactions between the synthesized complexes and target protein (the template structure Saccharomyces cerevisiae isomaltase), the mol. docking study was carried out.

JBIC, Journal of Biological Inorganic Chemistry published new progress about 366-18-7. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application of C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kondori, Tahere; Akbarzadeh-T, Niloufar; Ghaznavi, Habib; Karimi, Zeinab; Shahraki, Jafar; Sheervalilou, Roghayeh; Shahraki, Omolbanin published the artcile< A binuclear iron(III) complex of 5,5′-dimethyl-2,2′-bipyridine as cytotoxic agent>, Recommanded Product: 2,2′-Bipyridine, the main research area is binuclear iron complex dimethyl bipyridine cytotoxic agent; 5,5′-dimethyl-2,2′-bipyridine; Binuclear iron(III) complex; Cytotoxicity; Fish salmon DNA.

The binuclear iron(III) complex (1), namely, {[Fe(5,5′-dmbpy)2(OH2)]2(O)}(NO3)4 with a distorted octahedral coordination, formed by four nitrogen and two oxygen atoms, was previously reported by our team. In this study the DNA-binding and cytotoxicity evaluation for target complex were studied. The results indicated strong cytotoxicity activity against A549 cells comparable to cisplatin values. The binding interaction between complex 1 and FS-DNA was investigated by UV-Vis, fluorescence spectroscopy, and gel electrophoresis at physiol. pH (7.2). The DNA binding investigation has shown groove binding interactions with complex 1, therefore the hydrogen binding plays an important role in the interaction of DNA with complex 1. The calculated thermodn. parameters (ΔH°, ΔS° and ΔG°) show that hydrogen bonding and Vander-Waals forces have an important function in Fe(III) complex-DNA interaction. Moreover, DNA cleavage was studied using agarose gel electrophoresis. Viscosity measurements illustrated that relative viscosity of DNA was unchanged with the adding concentrations of Fe(III) complex. Mol. docking simulation results confirmed the spectroscopic and viscosity titration outcomes.

BioMetals published new progress about Bicyclic aromatic hydrocarbons Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Recommanded Product: 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sultan, Madiha; Kanavarioti, Anastassia published the artcile< Nanopore device-based fingerprinting of RNA oligos and microRNAs enhanced with an Osmium tag>, Name: 2,2′-Bipyridine, the main research area is RNA miRNA osmium nanopore device based fingerprinting.

Protein and solid-state nanopores are used for DNA/RNA sequencing as well as for single mol. anal. We proposed that selective labeling/tagging may improve base-to-base resolution of nucleic acids via nanopores. We have explored one specific tag, the Osmium tetroxide 2,2′-bipyridine (OsBp), which conjugates to pyrimidines and leaves purines intact. Earlier reports using OsBp-tagged oligodeoxyribonucleotides demonstrated proof-of-principle during unassisted voltage-driven translocation via either alpha-Hemolysin or a solid-state nanopore. Here we extend this work to RNA oligos and a third nanopore by employing the MinION, a com. available device from ONT. Conductance measurements demonstrate that the MinION visibly discriminates oligoriboadenylates with sequence A15PyA15, where Py is an OsBp-tagged pyrimidine. Such resolution rivals traditional chromatog., suggesting that nanopore devices could be exploited for the characterization of RNA oligos and microRNAs enhanced by selective labeling. This observation leads to the conjecture that the MinION/OsBp platform senses a 2-nucleotide sequence, in contrast to the reported 5-nucleotide sequence with native nucleic acids. Such improvement in sensing, enabled by the presence of OsBp, may enhance base-calling accuracy in enzyme-assisted DNA/RNA sequencing.

Scientific Reports published new progress about Fingerprint sensors. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Name: 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem