Category: 366-18-7

Acharjee, Animesh; Rakshit, Atanu; Chowdhury, Suman; Datta, Indukamal; Barman, Milan Krishna; Ali, Ansar Md.; Saha, Bidyut published the artcile< Micellar catalysed oxidation of hydrophobic fatty alcohol in aqueous medium>, Recommanded Product: 2,2′-Bipyridine, the main research area is octanol micellar catalyst oxidation mechanism kinetics.

Oxidation of a hydrophobic fatty alc. was carried out under pseudo 1st order reaction condition in aqueous micellar medium efficiently. In addition to the dissolution of alc. micelles are found to catalyze the oxidation reaction. Use of promoters further enhanced the rate of the reaction with almost instant completion of the reaction via the formation of active oxidants (AO+). The product was confirmed by IR and NMR study. Fluorescence studies and DLS measurements were done to confirm the formation of AO+. NMR studies were carried out to establish the interaction between the surfactants and 1-Octanol. Calculated activation parameters (ΔH≠, ΔS≠) also support the exptl. findings.

Journal of Molecular Liquids published new progress about Activation enthalpy. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Recommanded Product: 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Winter, Andreas; Endres, Patrick; Schroeter, Erik; Jaeger, Michael; Goerls, Helmar; Neumann, Christof; Turchanin, Andrey; Schubert, Ulrich S. published the artcile< Towards covalent photosensitizer-polyoxometalate dyads-bipyridyl-functionalized polyoxometalates and their transition metal complexes>, Computed Properties of 366-18-7, the main research area is hybrid materials; metal complexes; photocatalysis; polyoxometalates.

A triol-functionalized 2,2′-bipyridine (bpy) derivative has been synthesized and used for the tris-alkoxylation of polyoxometalate (POM) precursors. The resultant POM-bpy conjugates of the Wells-Dawson- and Anderson-type feature a C-C bond as a linkage between the POM and bpy fragments. This structural motif is expected to increase the hydrolytic stability of the compounds This is of particular relevance with respect to the application of POM-bpy metal complexes, as photocatalysts, in the hydrogen-evolution reaction (HER) in an aqueous environment. Accordingly, Rh(III) and Ir(III) complexes of the POM-bpy ligands have been prepared and characterized. These catalyst-photosensitizer dyads have been analyzed with respect to their electrochem. and photophys. properties. Cyclic and square-wave voltammetry, as well as UV/vis absorption and emission spectroscopy, indicated a negligible electronic interaction of the POM and metal-complex subunits in the ground state. However, emission-quenching experiments suggested an efficient intramol. electron-transfer process from the photo-excited metal centers to the POM units to account for the non-emissive nature of the dyads (thus, suggesting a strong interaction of the subunits in the excited state). In-depth photophys. investigations, as well as a functional characterization, i.e., the applicability in the HER reaction, are currently ongoing.

Molecules published new progress about 366-18-7. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Computed Properties of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Halevas, Eleftherios; Mavroidi, Barbara; Antonoglou, Orestis; Hatzidimitriou, Antonios; Sagnou, Marina; Pantazaki, Anastasia A.; Litsardakis, George; Pelecanou, Maria published the artcile< Structurally characterized gallium-chrysin complexes with anticancer potential>, Formula: C10H8N2, the main research area is gallium chrysin complex preparation cancer.

Chemotherapeutic metal-based compounds are effective anticancer agents; however, their cytotoxic profile and significant side effects limit their wide application. Natural products, especially flavonoids, are a prominent alternative source of anticancer agents that can be used as ligands for the generation of new bioactive complexes with metal ions of known biochem. and pharmacol. activities. Herein, we present the synthesis and detailed structural and physicochem. characterizations of three novel complex assemblies of Ga(III) with the flavonoid chrysin and the ancillary aromatic chelators 1,10-phenanthroline, 2,2′-bipyridine and imidazole. The complexes constitute the only crystallog. characterized structures having a metal core from the boron group elements and a flavonoid as the ligand. The in vitro biol. evaluation of the three complexes in a series of cancer cell lines of different origin established their cytotoxicity and ROS generating potential. In particular, the Ga(III)-chrysin-imidazole complex displayed the highest anticancer efficacy against all cancer cell lines with IC50 values in the low micromolar range (<1.18 μM), a result worth further investigation. Dalton Transactions published new progress about Antitumor agents. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Formula: C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Alper, Pinar; Erkisa, Merve; Genckal, Hasene Mutlu; Sahin, Saliha; Ulukaya, Engin; Ari, Ferda published the artcile< Synthesis, characterization, anticancer and antioxidant activity of new nickel(II) and copper(II) flavonoid complexes>, Recommanded Product: 2,2′-Bipyridine, the main research area is nickel copper naringenin quercetin bipyridine terpyridine flavonoid preparation; anticancer antioxidant activity nickel copper flavonoid complex.

Flavonoids are natural products which are known to have biol. activity for human health. In this study, new mixed ligand complexes of Ni(II) and Cu(II) were synthesized by using flavonoid (quercetin or naringenin) and heterocyclic imine (2,2′:6′,2”-terpyridine or 2,2′-bipyridine) ligands. The new complexes are [Ni(narH-1)(terpy)Cl].4H2O (1, nar = naringenin, terpy = 2,2′:6′,2”-terpyridine), [Cu(narH-1)(terpy)Cl].H2O (2), and [Cu(queH-1)(bpy)(O3N)].1.5H2O (3, que = quercetin, bpy = 2,2′-bipyridine). The structural features of the synthesized mixed ligand complexes were investigated using elemental anal., thermogravimetric anal., Fourier transform IR spectroscopy, magnetic susceptibility and molar conductivity measurements. The resulting data demonstrated an octahedral geometry for Complex 1 and Complex 2 and square pyramidal geometry for Complex 3. Antioxidant capacity and total phenolic content of Complexes 1-3 were measured by the Folin-Ciocalteu and ABTS methods. Antiproliferative effect of complexes were tested by SRB and ATP assays on MCF-7 (breast cancer), A549 (nonsmall cell lung cancer), PC-3 (prostate cancer) and HeLa (human cervical cancer) cell lines. Apoptosis was identified using by the fluorescence imaging, caspase cleaved cytokeratin-18 and flow cytometry anal. Complex 2 and 3 had high total phenolic content and antioxidant activity. Complex 2 was found to show selective cytotoxicity through the induction of apoptosis on MCF-7 cells with having a very low IC50 value (<0.8 μM; the half maximum inhibitory concentration) while its ligands showed much higher cytotoxicity (IC50 > 50 μM). In conclusion, Complex 2 is a highly promising and novel compound for breast cancer and warrants further animal experiments

Journal of Molecular Structure published new progress about Antioxidants. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Recommanded Product: 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chaubey, Surabhi; Yadav, Rajesh K.; Tripathi, Santosh K.; Yadav, Bal Chandra; Singh, Sudhir N.; Kim, Tae Wu published the artcile< Covalent Triazine Framework as an Efficient Photocatalyst for Regeneration of NAD(P)H and Selective Oxidation of Organic Sulfide>, Product Details of C10H8N2, the main research area is NADPH covalent triazine framework photocatalyst organic sulfide selective oxidation.

Covalent triazine frameworks (CTFs), belonging to the super-family of covalent organic frameworks, have attracted significant attention as a new type of photosensitizer due to the superb light-harvesting ability and efficient charge transfer originating from the large surface area. However, the wide optical band gap in CTFs, which is larger than 3.0 eV, hinders the efficient light harvesting in the visible range. To overcome this limitation, we developed the new type CTFs photocatalyst based on the donor-acceptor conjugation scheme by using melamine (M) and 2,6-diaminoanthraquinone (AQ) as monomeric units. The melamine-2,6-diaminoanthraquinone-based covalent triazine frameworks (M-AQ-CTFs) photocatalyst shows the excellent light-harvesting capacity with high molar extinction coefficient, and the suitable optical band gap involving the internal charge transfer character. Combination of M-AQ-CTFs and artificial photosynthetic system including the organometallic rhodium complex, acting as an electron mediator, exhibited the excellent photocatalytic efficiency for the regeneration of the nicotinamide cofactors such as NAD(P)H. In addition, this photocatalyst showed the high photocatalytic efficiency for the metal-free aerobic oxidation of sulfide. This study demonstrates the high potential of CTFs photocatalyst with the donor-acceptor conjugated scheme can be actively used for artificial photosynthesis.

Photochemistry and Photobiology published new progress about Anaerobic oxidation. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Product Details of C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hussain, Afzal; AlAjmi, Mohamed Fahad; Rehman, Tabish Md.; Amir, Samira; Husain, Fohad Mabood; Alsalme, Ali; Siddiqui, Maqsood Ahmad; AlKhedhairy, Abdulaziz A.; Khan, Rais Ahmad published the artcile< Copper(II) complexes as potential anticancer and Nonsteroidal anti-inflammatory agents: In vitro and in vivo studies>, Electric Literature of 366-18-7, the main research area is copper complex anticancer nonsteroidal antiinflammatory agent breast cancer.

Copper-based compounds are promising entities for target-specific next-generation anticancer and NSAIDS therapeutics. In lieu of this, benzimidazole scaffold plays an important role, because of their wide variety of potential functionalizations and coordination modes. Herein, we report three copper complexes 1-3 with benzimidazole-derived scaffolds, a biocompatible mol., and secondary ligands viz, 1-10-phenanthroline and 2,2′-bipyridyl. All the copper complexes have been designed, synthesized and adequately characterized using various spectroscopic techniques. In-vitro, human serum albumin (HSA) binding was also carried out using fluorescence technique and in-silico mol. modeling studies, which exhibited significant binding affinities of the complexes with HSA. Furthermore, copper complexes 1-3 were tested for biol. studies, i.e., anticancer as well as NSAIDS. In vitro cytotoxicity results were carried out on cultured MCF-7 cell lines. To get the insight over the mechanism of action, GSH depletion and change in lipid peroxidation were tested and thus confirmed the role of ROS generation, responsible for the cytotoxicity of the complexes 1-3. Moreover, the copper complexes 1-3 were tested for potential to act as NSAIDS on albino rats and mice in animal studies in-vivo. Addnl., we also predicted the mechanism of action of the copper complexes 1-3 using mol. modeling studies with COX-2 inhibitor.

Scientific Reports published new progress about Analgesics. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Electric Literature of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dalal, Anuj; Nehra, Kapeesha; Hooda, Anjli; Singh, Sitender; Singh, Devender; Kumar, Sumit published the artcile< Synthesis, Optoelectronic and Photoluminescent Characterizations of Green Luminous Heteroleptic Ternary Terbium Complexes>, Application In Synthesis of 366-18-7, the main research area is green luminous heteroleptic ternary terbium complexe optoelectronic photoluminescence property; 2,2’-Bipyridine; Color purity; Fluorescence; Tauc’s relation; Ternary terbium complexes.

This article presents four ternary terbium complexes based on fluorinated 2-thenoyltrifluoroacetone (TTFA) and N donor bidentate neutral ligands. The prepared complexes were examined by elemental study, electrochem. anal., spectroscopically and thermo-gravimetrically. Spectral anal. shows the bonding of Tb3+ ion with oxygen and nitrogen atom of diketone and neutral ligand resp. Upon excitation in UV region, synthesized terbium complexes show luminescence in green region of electromagnetic spectrum. Photoluminescence emission spectra of complexes do not show any ligand based peak suggesting the effective transferal of energy from ligand to metal ion. Green emanation by terbium complexes is owing to intense peak ∼547 nm (5D4 → 7F5). The outcome of emission data and CIE coordinates correlate with each other and affirms the utility of green luminous complexes as potential emissive material for optoelectronic gadgets applied in lighting system.

Journal of Fluorescence published new progress about Cyclic voltammetry. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application In Synthesis of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tang, Yinghong; Zhai, Jingying; Chen, Qinghan; Xie, Xiaojiang published the artcile< Ruthenium bipyridine complexes as electrochemiluminescent transducers for ionophore-based ion-selective detection>, Synthetic Route of 366-18-7, the main research area is .

We report here a method to determine target ion concentrations (with Na+ as a model) based on ionophores and electrochemiluminescence (ECL). Ruthenium bipyridine complexes were released from thin polymeric films (plasticized poly(vinyl chloride) also containing a sodium ionophore) into the sample solution following an explicit ion-exchange process (between Na+ and the ruthenium complex). Two signal transducers, tris(2,2′-(pCF3)bipyridine)ruthenium(II) (Ru(p-CF3-bpy)32+) and tris(2,2′-bipyridyl)dichlororuthenium(II) (Ru(bpy)32+), were examined using the sensing film, with the latter providing a more sensitive detection range (ca. 1 to 100 μM) than that of the more hydrophobic one (0.01 to 1 mM). While the ionophore (Na+ ionophore X) offered excellent selectivity to the method, the ruthenium complexes made the measurements independent of the sample pH. Furthermore for complex biol. samples such as blood serum, an indirect approach of measuring the ECL of the remaining ruthenium complexes helps avoid background matrix interference to the ECL production at the working electrode, making the ECL method more attractive for real complex samples.

Analyst (Cambridge, United Kingdom) published new progress about 366-18-7. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Synthetic Route of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nagieva, I. T.; Ali-zadeh, N. I.; Nagiev, T. M. published the artcile< Coherent synchronization of pyridine dimerization reactions and decomposition of ""green oxidants""- H2O2 and N2O>, Synthetic Route of 366-18-7, the main research area is pyridine dimer preparation.

The reaction of pyridine oxidation by hydrogen peroxide and nitrous oxide under homogeneous conditions, in the gas phase, without the use of catalysts, at atm. pressure, was exptl. investigated. Areas of selective oxidation of pyridine with hydrogen peroxide and nitrous oxide were established, and optimal conditions were found for obtaining valuable raw materials required in the petrochem., chem., and pharmaceutical industries.

Azerbaidzhanskii Khimicheskii Zhurnal published new progress about Dimerization. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Synthetic Route of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Segawa, Yasutomo; Levine, David R.; Itami, Kenichiro published the artcile< Topologically Unique Molecular Nanocarbons>, Electric Literature of 366-18-7, the main research area is topol mol nanocarbon organic mol.

As new forms of carbon are unearthed, they invariably transform the scientific landscape. Numerous researchers have been inspired to discover the unique characteristics of these fascinating materials, consistently leading to the development of important technol. innovations in materials science. Recently, studies on the preparation of mol. nanocarbons (small mol. analogs of larger carbon nanostructures) by precision organic synthesis have attracted much attention. Cycloparaphenylene (CPP), the substructure of carbon nanotubes (CNTs), is the oldest of such organic mols., and since 2008 the successful synthesis of CPP dramatically advanced the synthetic chem. of mol. nanocarbons. In fact, as pioneering research, we succeeded in producing carbon nanotubes using seed CPP mols. in 2013. This method represented an important landmark in the quest for controlling the diameter of CNTs via utilization of a well-defined small mol. as a template. Other avenues of research on graphene nanoribbons and partial structures of fullerenes such as corannulene and sumanene are also highly active at the current time. On the other hand, carbon forms with nontrivial topologies, i.e., topol. nanocarbons, are virtually unexplored. In addition to the 3D network structures represented by the Mackay crystal, many topol. complex structures have been envisioned. To date, there is no rational approach toward the bottom-up synthesis of these carbon structures. As with the case of fullerenes and CNTs, access to these unique carbon structures should undoubtedly revolutionize a wide range of sciences. This Account highlights our efforts toward the synthesis of topol. unique mol. nanocarbons. Starting from CPP as the topol. simple subunit, we have successfully created novel mol. nanocarbons that have more complexed topologies. The first topic is carbon nanobelts, fully fused cylinder-shaped mol. nanocarbons representing the segment structure of armchair-type CNTs. The second topic is carbon nanocages, mol. nanocarbons having a “”three-holed”” topol. representing the joint unit of branched CNTs. The third and fourth topics are all-benzene catenanes consisting of two CPP rings and an all-benzene trefoil knot topol. related to a carbon nanotorus. The world of nanocarbon mols. is only limited by our imagination and creativity. As history has proved, the synthesis of new forms of carbon and topol. complex mols. has always subsequently led to new fields and applications associated with their unforeseen properties and functions.

Accounts of Chemical Research published new progress about Carbon nanotubes. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Electric Literature of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem