Category: 366-18-7

Impert, Olga; Kozakiewicz, Anna; Wrzeszcz, Grzegorz; Katafias, Anna; Bienko, Alina; van Eldik, Rudi; Ozarowski, Andrew published the artcile< Characterization of a Mixed-Valence Ru(II)/Ru(III) Ion-Pair Complex. Unexpected High-Frequency Electron Paramagnetic Resonance Evidence for Ru(III)-Ru(III) Dimer Coupling>, Name: 2,2′-Bipyridine, the main research area is ruthenium picolinate bipyridine complex preparation EPR DFT magnetic property; crystal structure ruthenium picolinate bipyridine.

In this contribution, we report the synthesis and full characterization of the first mixed-valence Ru(II)/Ru(III) ion-pair complex, [RuII(bipy)2(pic)]+[cis-RuIIICl2(pic)2]-, in the solid state and in aqueous solution, where bipy = 2,2′-bipyridine and pic- = picolinate. In addition, unexpected high-frequency ESR evidence for interactions between two neighboring Ru(III) ions, resulting in a triplet state, S = 1, was found.

Inorganic Chemistry published new progress about Crystal structure. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Name: 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Constable, Edwin C.; Housecroft, Catherine E. published the artcile< The early years of 2,2'-bipyridine-a ligand in its own lifetime>, Electric Literature of 366-18-7, the main research area is 2,2’-bipyridine; coordination chemistry; history; supramolecular chemistry; synthesis.

The first fifty years of the chem. of 2,2′-bipyridine are reviewed from its first discovery in 1888 to the outbreak of the second global conflict in 1939. The coordination chem. and anal. applications are described and placed in the context of the increasingly sophisticated methods of characterization which became available to the chemist in this time period. Many of the “”simple”” complexes of 2,2′-bipyridine reported in the early literature have been subsequently shown to have more complex structures.

Molecules published new progress about 366-18-7. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Electric Literature of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Al-Busaidi, Idris Juma; Ilmi, Rashid; Zhang, Danyang; Dutra, Jose D. L.; Oliveira, Willyan F.; Al Rasbi, Nawal K.; Zhou, Liang; Wong, Wai-Yeung; Raithby, Paul R.; Khan, Muhammad S. published the artcile< Synthesis and photophysical properties of ternary β-diketonate europium(III) complexes incorporating bipyridine and its derivatives>, COA of Formula: C10H8N2, the main research area is trifluoromethyl phenyl butanedione phenylethynyl bromo bipyridine europium preparation photophys; ternary beta diketonate europium bipyridine preparation photophys photoluminescence.

Two new octa-coordinated ternary europium(III) complexes of the type [Eu(btfa)3(Br2-bpy)] (Eu-1) and [Eu(btfa)3(PhE2-bpy)] (Eu-2) (where btfa = 4,4,4-trifluoro-1-phenyl-1,3-butanedione, Br2-bpy = 5,5′-dibromo-2,2′-bipyridine, PhE2-bpy 5,5′-bis(phenylethynyl)-2,2′-bipyridine) together with a previously reported complex [Eu(btfa)3(bpy)] (Eu-3) have been synthesized. The complexes have been characterized by anal. and spectroscopic methods. The photophys. properties of the complexes have also been analyzed both exptl. and theor. The contribution of each ligand to the sensitized Eu(III) photoluminescence (PL) has been analyzed and is discussed. An energy transfer (ET) mechanism is proposed and discussed for the sensitized Eu(III) emission using exptl. and theor. data. The Eu(III) complex incorporating the parent bpy showed impressive performance as a double-emitting layer (EML) red organic light emitting diodes (R-OLEDs).

Dyes and Pigments published new progress about Crystal structure. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, COA of Formula: C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lv, Tengteng; Dai, Fa; Zhuang, Qiuting; Zhao, Xuelin; Shao, Yina; Guo, Ming; Lv, Zhimeng; Li, Chenghua; Zhang, Weiwei published the artcile< Outer membrane protein OmpU is related to iron balance in Vibrio alginolyticus>, Electric Literature of 366-18-7, the main research area is Vibrio outer membrane porin iron; Iron balance; OmpU; Vibrio alginolyticus.

Outer membrane protein U (OmpU) is a major porin from Vibrio alginolyticus and has been considered a vaccine candidate against infection by V. alginolyticus. After pre-incubated with polyclonal antibody against rOmpU, V. alginolyticus showed a 78% decrease in extracellular iron level, suggesting that interruption of OmpU could increase intracellular iron level. The mRNA expression of ompU under iron-limited conditions was determined using real-time reverse transcriptase PCR. The mRNA level of ompU was downregulated to 0.27-, 0.036- and 0.019-fold after the addition of the iron chelator 2,2′-bipyridyl for 10, 30 and 60 min, resp. In addition, the promoter of ompU contained a ferric uptake regulator (Fur) binding site, which revealed the potential regulation of ompU by Fur and iron. Fur from V. alginolyticus was purified and used for electrophoretic mobility shift assay. The result showed that in the absence of Fe2+, purified recombinant Fur could specifically bind to the promoter DNA of ompU, while in the presence of Fe2+, the binding of Fur and the promoter DNA was suppressed. Our study preliminarily explored the function of OmpU in iron balance in V. alginolyticus, and these findings were helpful in understanding iron metabolism in V. alginolyticus.

Microbiological Research published new progress about Major outer membrane porins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Electric Literature of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Demakov, Pavel A.; Ryadun, Alexey A.; Dorovatovskii, Pavel V.; Lazarenko, Vladimir A.; Samsonenko, Denis G.; Brylev, Konstantin A.; Fedin, Vladimir P.; Dybtsev, Danil N. published the artcile< Intense multi-colored luminescence in a series of rare-earth metal-organic frameworks with aliphatic linkers>, Application of C10H8N2, the main research area is rare metal organic framework aliphatic linker multicolored luminescence.

Two series of highly luminescent yttrium(III), europium(III) and terbium(III) metal-organic frameworks containing diimine aromatic ligands and the dicarboxylate linker trans-1,4-cyclohexanedicarboxylate (chdc2-) which can be described by the general formulas [M2(bpy)2(chdc)3], where M = Y3+ (1), Eu3+ (2), and Tb3+ (3) and bpy = 2,2′-bipyridyl, and [M2(phen)2(chdc)3], where M = Y3+ (4), Eu3+ (5), and Tb3+ (6) and phen = 1,10-phenanthroline, were synthesized and characterized. All compounds are based on the same dinuclear {M2(L)2(OOCR)6} building blocks and possess a similar topol. of the 3D framework with narrow pores. The chelate aromatic ligands act as efficient light-harvesting antennas for subsequent energy transfer to the emitting metal center (M = Eu3+, Tb3+) or intraligand photoemission (M = Y3+). As a result, the reported compounds display intense emission in the red (Eu3+), green (Tb3+) or blue (Y3+) regions representing three basic colors (RGB) of visible light. The measured quantum yields (QYs) of the solid-state luminescence for individual compounds were found to be 63% (1), 46% (2), 59% (3), 2.3% (4), 55% (5) and 49% (6). The drastic reduction of the luminescence efficiency for 4 is explained by the strong disorder of phen ligands. The high thermal stability (up to 300 °C) and exceptional moisture resistance of the bpy-based frameworks 1-3 were confirmed by TG and PXRD measurements. Various bimetal or trimetal compositions were also prepared for the bpy-series. The luminescence properties of these mixed-metal compounds depend on both the chem. composition and excitation wavelength (λex). Remarkably, pure white emission with color temperature = 6126 K was achieved for [Y1.68Eu0.08Tb0.24(bpy)2(chdc)3] at λex = 360 nm with QY = 20%. The reported results suggest that the obtained coordination framework series is a convenient platform for the design of highly efficient light emitting materials with tunable properties.

Dalton Transactions published new progress about Crystal structure. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application of C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Thuery, Pierre; Harrowfield, Jack published the artcile< Contrasting Structure-Directing Effects in the Uranyl-Phthalate/Isophthalate Isomer Systems>, Category: pyridine-derivatives, the main research area is crystal growth mol structure directing uranyl phthalate isophthalate isomer.

Reaction of uranyl cations with phthalic (H2pht) or isophthalic (H2ipht) acids under solvohydrothermal conditions was performed in the presence of 3d-block metal cations associated with chelating nitrogen donors to give nine zero-, mono-, and diperiodic complexes. [UO2(pht)2Zn(phen)2]2·4H2O (1), where phen is 1,10-phenanthroline, is a heterometallic, tetranuclear complex, while the counterion separation in [Ni(bipy)3][UO2(pht)(NO3)]2 (2), where bipy is 2,2′-bipyridine, yields a monoperiodic, helical uranyl ion complex crystallizing in a pure enantiomeric form. The diperiodic network in [Ni(phen)3][(UO2)3(O)(pht)3]·6H2O (3) displays pseudotrigonal, cuplike cavities containing part of the bulky counterions. [(UO2)2(O)(pht)2Ni(cyclam)(H2O)]2·H2O (4), where cyclam is 1,4,8,11-tetraazacyclotetradecane, is a discrete, bis(μ3-oxo)-bridged tetranuclear uranyl complex of common geometry, to which two Ni(cyclam)2+ moieties are attached through oxo bonding to uranyl. Separation of the 3d-block metal ion complex in [Ni(cyclam)]2[(UO2)7(pht)8(NO3)2] (5) and [Cu(R,S-Me6cyclam)][(UO2)5(O)2(pht)4(H2O)2]·4H2O (6), where R,S-Me6cyclam is 7(R),14(S)-5,5,7,12,12,14-hexamethylcyclam, results in the formation of quasi-planar diperiodic networks hydrogen bonded to the counterions. The three isophthalate complexes [(UO2)2(ipht)3Cu(bipy)2]·H2O (7), [(UO2)2(ipht)2(HCOO)2Ni(cyclam)] (8), and [(UO2)2(ipht)2(HCOO)2Cu(R,S-Me6cyclam)] (9) crystallize as heterometallic diperiodic species with Cu(bipy)22+ being only decorating in 7, while Ni2+ and Cu2+ in 8 and 9 bridge uranyl-containing chains into a network with a V2O5 topol.

Crystal Growth & Design published new progress about Crystal growth. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gu, Jin-Zhong; Wan, Shi-Mao; Dou, Wei; Kirillova, Marina V.; Kirillov, Alexander M. published the artcile< Coordination polymers from an unexplored biphenyl-tricarboxylate linker: hydrothermal synthesis, structural traits and catalytic cyanosilylation>, Safety of 2,2′-Bipyridine, the main research area is coordination polymer biphenyl tricarboxylate linker hydrothermal synthesis catalytic cyanosilylation.

A novel biphenyl-tricarboxylic acid, 3,2′,4′-biphenyl-tricarboxylic acid (H3bta), was used as a versatile linker for preparing a new series of nickel(II), zinc(II), and cadmium(II) coordination polymers (CPs) and complexes, formulated as {[Cd(μ-Hbta)(2,2′-bipy)(H2O)]·3H2O}n (1), {[Ni(μ-Hbta)(4,4′-bipy)(H2O)3]·H2O}n (2), [M2(μ-Hbta)2(4,4′-bipy)2(H2O)2]·2H2O (M = Zn (3) and Cd (4)), {[Cd2(μ4-bta)(μ-Cl)(phen)2]·2H2O}n (5). {[Zn2(μ3-bta)(2,2′-bipy)2(H2O)3][Zn(μ-bta)(2,2′-bipy)(H2O)]·3H2O} (6), {[Cd3(μ4-bta)2(2,2′-bipy)3]·4H2O}n (7), {[Zn3(μ3-bta)2(H2biim)2(μ-H2biim)(H2O)2]·2H2O}n (8), and [Zn3(μ6-bta)2(py)2]n (9). These coordination compounds were hydrothermally assembled from the metal(II) chlorides, H3bta as a principal building block and N-donor ancillary ligands as crystallization mediators (i.e., 2,2′-bipyridine, 2,2′-bipy; 4,4′-bipyridine, 4,4′-bipy; 1,10-phenanthroline, phen; 2,2′-biimidazole, H2biim; or pyridine, py). All the synthesized products 1-9 were characterized by standard solid-state methods including elemental anal., IR spectroscopy, thermogravimetric anal. (TGA), powder X-ray diffraction (PXRD) and single-crystal X-ray diffraction. The structures of 1-9 range from 0D dimers (3 and 4) to 1D coordination polymers (1, 2, 5, and 6) and 2D metal-organic layers (7-9). Such a diversity of structures is explained by the differences in metal(II) centers, deprotonation levels of H3bta, and crystallization mediators. From a topol. perspective, the obtained structures include 2C1 chains (in 1, 2, and 6), pcu H-bonded nets (in 3 and 4), SP 1-periodic nets (in 5), and 4,5L51 (in 7) and hcb (in 8) layers. For compounds 1-9, luminescence properties were also evaluated. Besides, the catalytic behavior of the obtained products was screened in the cyanosilylation of benzaldehydes with trimethylsilyl cyanide to give cyanohydrin products under mild conditions, including an optimization of various reaction parameters and an investigation of the substrate scope. Among the tested compounds, 3 acts as the most efficient and recyclable heterogeneous catalyst with up to 96% product yields. By presenting the unique examples of coordination compounds derived from H3bta, this study introduces its use as a new tricarboxylate linker for assembling functional coordination polymers and metal complexes.

Inorganic Chemistry Frontiers published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Safety of 2,2′-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Eremina, Julia A.; Lider, Elizaveta V.; Samsonenko, Denis G.; Sheludyakova, Liliya A.; Berezin, Alexey S.; Klyushova, Lyubov S.; Ostrovskii, Vladimir A.; Trifonov, Rostislav E. published the artcile< Mixed-ligand copper(II) complexes with tetrazole derivatives and 2,2'-bipyridine, 1,10-phenanthroline: Synthesis, structure and cytotoxic activity>, Category: pyridine-derivatives, the main research area is crystal structure copper phenanthroline bipyridine tetrazole; copper phenanthroline bipyridine phenyltetrazole tetrazole preparation cytotoxicity human.

The [Cu2(2,2′-bipy)2(L1)4] (1), [Cu2(1,10-phen)2(L1)4] (2), [Cu(2,2′-bipy)(L2)2]n (3) and [Cu2(1,10-phen)2(L2)4] (4) complexes, where HL1 – 5-phenyltetrazole, and HL2 – 1H-tetrazole, were synthesized. All complexes were characterized by elemental anal., IR, EPR spectroscopy and x-ray diffraction. The complexes possess distorted tetragonal-pyramidal coordination geometry. Compounds 1, 2, and 4 show μ-5-phenyl-tetrazole/tetrazole bridged dinuclear structures, while compound 3 reveals polymeric structure. The effect of the compounds on viability of the MCF-7 and Hep-2 cell lines was studied in vitro. Tetrazole ligands HL1 and HL2 are nontoxic at tested concentrations (1-50 μM), while 1,10-phen and 2,2′-bipy possess cytotoxicity. All of the complexes exhibit significant dose-dependent cytotoxic effect and have the potential to act as efficient cytotoxic drugs. [Cu(1,10-phen)Cl2] (5) and [Cu(2,2′-bipy)Cl2] (6) also were obtained to establish the influence of insertion of tetrazole ligands in compounds on their cytotoxic properties.

Inorganica Chimica Acta published new progress about Antitumor agents. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chen, Dandan; Zhao, Qunfei; Liu, Wen published the artcile< Discovery of caerulomycin/collismycin-type 2,2'-bipyridine natural products in the genomic era>, Reference of 366-18-7, the main research area is review caerulomycin collismycin bipyridine bioactive natural product genomic era; 2,2′-Bipyridine; Caerulomycin; Collismycin; Natural product discovery; Natural products.

A review. 2,2′-Bipyridine (2,2′-BP) is the unique mol. scaffold of the bioactive natural products represented by caerulomycins (CAEs) and collismycins (COLs). CAEs and COLs are highly similar in the chem. structures in which their 2,2′-BP cores typically contain a di- or tri-substituted ring A and an unmodified ring B. Here, we summarize the CAE and COL-type 2,2′-BP natural products known or hypothesized to date: (1) isolated using methods traditional for natural product characterization, (2) created by engineering the biosynthetic pathways of CAEs or COLs, and (3) predicted upon bioinformatics-guided genome mining. The identification of these CAE and COL-type 2,2′-BP natural products not only demonstrates the development of research techniques and methods in the field of natural product chem. but also reflects the general interest in the discovery of CAE and COL-type 2,2′-BP natural products.

Journal of Industrial Microbiology & Biotechnology published new progress about Bioinformatics. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Reference of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zeng, L.; Sirbu, D.; Waddell, P. G.; Tkachenko, N. V.; Probert, M. R.; Benniston, A. C. published the artcile< Hydrogen peroxide assisted photorelease of an anthraquinone-based ligand from [Ru(2,2'-bipyridine)2(9,10-dioxo-9,10-dihydroanthracen-1-olate)]Cl in aqueous solution>, Application In Synthesis of 366-18-7, the main research area is ruthenium hydroxyanthraquinone bipy complex preparation redox potential antitumor CD; crystal structure ruthenium hydroxyanthraquinone bipy complex.

A new class of light-activated ruthenium(II) complex was designed as a potential blocker of biol. functioning, especially for targeting redox reactions within mitochondria under light activation. Based on our concepts the complex [Ru(bipy)2(1-hydroxyanthra-9,10-quinone)]Cl (RU1) was prepared and studied to understand the preliminary reaction mechanisms and its excited state behavior through a series of stability tests, electrochem., UV-Visible kinetics and femtosecond transient absorption spectroscopy experiments Under white light in the presence of H2O2 two different reactions (fast and slow) appear to take place. The complex loses the quinone-based ligand and a resulting Ru(III) or Ru(V) species is produced. The complex RU1 shows potential to consume H2O2 from the one carbon metabolism in mitochondria, and hence may cut the energy cycle pathway of tumor cells.

Dalton Transactions published new progress about Antitumor agents. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application In Synthesis of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem