Category: 4088-62-4

Martinez-Barrasa, Valentin et al. published their research in Tetrahedron in 2000 | CAS: 4088-62-4

3,5-Dichloro-N-methylpyridin-2-amine (cas: 4088-62-4) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 3,5-Dichloro-N-methylpyridin-2-amine

Pyridinium N-(2′-azinyl)aminides: regioselective synthesis of 2-alkylaminoazines was written by Martinez-Barrasa, Valentin;Delgado, Francisca;Burgos, Carolina;Garcia-Navio, J. Luis;Izquierdo, M. Luisa;Alvarez-Builla, Julio. And the article was included in Tetrahedron in 2000.Recommanded Product: 3,5-Dichloro-N-methylpyridin-2-amine The following contents are mentioned in the article:

The regioselective alkylation of pyridinium-N-(2-azinil)aminides with alkyl halides under mild conditions is described. The alkylation, combined with a reduction of the N-N bond, allows an easy preparation of 2-alkylaminoazines. This study involved multiple reactions and reactants, such as 3,5-Dichloro-N-methylpyridin-2-amine (cas: 4088-62-4Recommanded Product: 3,5-Dichloro-N-methylpyridin-2-amine).

3,5-Dichloro-N-methylpyridin-2-amine (cas: 4088-62-4) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 3,5-Dichloro-N-methylpyridin-2-amine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Brown, D. J. et al. published their research in Journal of the Chemical Society in 1965 | CAS: 4088-62-4

3,5-Dichloro-N-methylpyridin-2-amine (cas: 4088-62-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Recommanded Product: 4088-62-4

The Dimroth rearrangement. IV. A study of facilitation by electron-withdrawal. Alkylated 2-alkyliminopyrimidines was written by Brown, D. J.;Harper, J. S.. And the article was included in Journal of the Chemical Society in 1965.Recommanded Product: 4088-62-4 The following contents are mentioned in the article:

cf. CA 63, 7006d. The rates of Dimroth rearrangement of nuclear N-methylated 2-and 4-iminopyrimidines are increased by the electron-withdrawal provided by a 5-bromo substituent, and much more by the greater electron-attracting power of a 5-nitro group. 1-Benzyl-1,2-dihydro-2-methyliminopyrimidine largely rearranges into 2-benzylimino-1,2-dihydro-1-methylpyrimidine, but the reverse reaction is not detectable by ultraviolet spectral means. Unlike the pyrimidine analogs, 1,2-dihydro-2-imino-1-methylpyridine and its 5-chloro-, 3,5-dichloro-, and 5-cyano derivatives do not rearrange. Only in its 3- and 5-nitro derivatives is there sufficient localization of 蟺-electrons to permit easy rearrangement. This study involved multiple reactions and reactants, such as 3,5-Dichloro-N-methylpyridin-2-amine (cas: 4088-62-4Recommanded Product: 4088-62-4).

3,5-Dichloro-N-methylpyridin-2-amine (cas: 4088-62-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Recommanded Product: 4088-62-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem